Verfahren zur Herstellung von N-Alkylanilinen
    61.
    发明公开
    Verfahren zur Herstellung von N-Alkylanilinen 失效
    一种用于制备N-烷基苯胺处理。

    公开(公告)号:EP0327874A2

    公开(公告)日:1989-08-16

    申请号:EP89101169.4

    申请日:1989-01-24

    申请人: BAYER AG

    IPC分类号: C07C209/22 C07C211/48

    CPC分类号: C07C209/64

    摘要: N-Alkylaniline können durch Umsetzung von Anilinen mit N,N-Dialkylanilinen in der Gas- oder Sumpfphase bei erhöhter Temperatur hergestellt werden, indem man die Umsetzung in Gegenwart von Zeolithen durchführt.

    摘要翻译: 的N-烷基苯胺可以通过用N,气体或在升高的温度下的液相中生产N-二烷基苯胺,通过进行在沸石的存在下进行反应的苯胺反应来制备。

    Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters
    63.
    发明公开
    Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters 失效
    经皮治疗疼痛和炎症与2-氨基-3-aroylbenzolessigsäuren,它们的盐和酯。

    公开(公告)号:EP0221753A2

    公开(公告)日:1987-05-13

    申请号:EP86308373.9

    申请日:1986-10-28

    CPC分类号: A61K31/195 A61K31/215

    摘要: Pain and or inflammatio is treated by transdermal administration of 2-amino-3-benzoyl-benzeneacetic acids, salts and esters having the formula
    wherein R' is hydrogen, loweralkyl or a pharmaceutically acceptable cation R 2 is hydrogen, halogen, loweralkyl or loweralkoxy; R', R 4 and R 6 are hydrogen or loweralkyl; X is hydrogen, halogen. foweralkyl, hydroxy, loweralkoxy, nitro, trifluoromethyl or loweralkylthio; Y is hydrogen, loweralkyl, loweralkoxy, nitro or trifluoromethyl and hydrates and alcoholates thereof.

    摘要翻译: 疼痛和炎症或由具有下式的2-氨基-3-苯甲酰基 - 苯乙酸,盐和酯透皮给药治疗...... worin - [R <1>是氢,低级烷基或药学上可接受的阳离子; [R <2>为氢,卤素,低级烷基或低级烷氧基; [R <3>,R <4>和R <5>是氢或低级烷基; X是氢,卤素,低级烷基,羟基,低级烷氧基,硝基,三氟甲基或loweralkylthio; Y是氢,低级烷基,低级烷氧基,硝基或三氟甲基和水合物和醇化物体。

    Preparation process of indole
    65.
    发明公开
    Preparation process of indole 失效
    一种吲哚的制备方法。

    公开(公告)号:EP0183160A1

    公开(公告)日:1986-06-04

    申请号:EP85114623.3

    申请日:1985-11-18

    IPC分类号: C07D209/08 C07C211/48

    CPC分类号: C07D209/08

    摘要: A process for producing an indole which comprises reacting an aniline and a diol in the presence of a catalyst to produce a reaction mixture containing the indole, unreacted aniline and by-products, condensing the reaction mixture to obtain a liquid reaction product, recovering the unreacted aniline from the liquid reaction product, reducing the contents of specified by-products in the recovered aniline below specified levels and reutilizing the resulting recovered aniline. To reduce the contents of the specified by-products in the recovered aniline below specified levels, it is preferred to subject the liquid reaction product or an aniline fraction separated therefrom to a heat-treatment and then to distillation. In the above manner, the recovered aniline can be reutilized in the reaction without causing the activity of the catalyst to deteriorate.

    CROSS-COUPLING REACTION CATALYST
    69.
    发明公开

    公开(公告)号:EP3845308A1

    公开(公告)日:2021-07-07

    申请号:EP19853932.2

    申请日:2019-08-28

    摘要: It is an object of the present invention to provide a catalyst for a cross-coupling reaction in which an organometallic complex is sufficiently immobilized on a carrier and an object product can be easily obtained in a high yield and in a relatively short reaction time with a relatively small amount of use. The catalyst for a cross-coupling reaction of the present invention has a carrier part composed of a synthetic resin and an organometallic complex part immobilized on the carrier part by chemical bonding, and has a structure represented by formula (P1), wherein in (P1) R 1 , R 2 may be the same or different, and is a substituent such as a hydrogen atom. R 3 , R 4 , R 5 , R 6 , R 8 , R 9 may be the same or different and are substituents, such as a hydrogen. X represents a halogen atom, and R 7 represents a substituent having 3 to 20 carbon atoms with a Π bond. RS1 represents the main chain of the synthetic resin precursors having -CH 2 OH group at their end.