7,8-Dihydroimidazo-(1,5-a)-Pyrazin-8-ones
    62.
    发明公开
    7,8-Dihydroimidazo-(1,5-a)-Pyrazin-8-ones 失效
    7,8-二氢咪唑(1,5-A) - 吡嗪-8- ONES

    公开(公告)号:EP0152077A3

    公开(公告)日:1986-07-23

    申请号:EP85101356

    申请日:1985-02-08

    摘要: Provided are compounds of the structure:
    and pharmaceutically acceptable salts thereof, wherein R 1 , R 3 , R 5 and R 6 are independently H, alkyl, aralkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkenyl, alkynyl, hydroxy, hydroxyalkyl, alkoxy, mercapto, mercaptoalkyl, alkylthio, amino, alkylamino, aminoalkyl, formyl, carboxy, carbalkoxy, alkanoyl, cyano, nitro, halo, trifluoromethyl, alkylsulfonyl, aminosulfonyl, carbamoyl or cycloalkyl; and
    R 7 is H, alkyl, aryi, aralkyl, oxo, or alkanoyl;
    wherein at least one of R 1 , R 5 or R 6 is an aryl, heteroaryl, or heteroaryl substituted with H, alkyl, halo, amino, trifluoromethyl or cyano.