公开(公告)号：EP2079383A4

公开(公告)日：2011-01-05

申请号：EP07861943

申请日：2007-11-13

申请人： TOPCON MEDICAL LASER SYSTEMS INC

发明人： PALANKER DANIEL V ,  ANDERSEN DAN

IPC分类号： A61B18/18

CPC分类号： A61F9/00821 ,  A61B3/102 ,  A61B18/20 ,  A61B90/361 ,  A61B2018/20351 ,  A61F9/008 ,  A61F2009/00851 ,  A61F2009/00855 ,  A61F2009/00863 ,  A61F2009/00868 ,  A61F2009/00885 ,  A61F2009/00897 ,  A61N5/0622

摘要： A system and method for treating ophthalmic target tissue, including a light source for generating a beam of light, a beam delivery system that includes a scanner for generating patterns, and a controller for controlling the light source and delivery system to create a dosimetry pattern of the light beam on the ophthalmic target tissue. One or more dosage parameters of the light beam vary within the dosimetry pattern, to create varying exposures on the target tissue. A visualization device observes lesions formed on the ophthalmic target tissue by the dosimetry pattern. The controller selects dosage parameters for the treatment beam based upon the lesions resulting from the dosimetry pattern, either automatically or in response to user input, so that a desired clinical effect is achieved by selecting the character of the lesions as determined by the dosimetry pattern lesions.

摘要翻译： 一种用于治疗眼睛靶组织的系统和方法，包括用于产生光束的光源，包括用于产生图案的扫描仪的束传送系统，以及用于控制光源和传送系统以创建剂量学模式的控制器 光束在眼睛靶组织上。 光束的一个或多个剂量参数在剂量测定模式内变化，以在靶组织上产生不同的曝光。 可视化装置通过剂量测定模式观察在眼睛靶组织上形成的损伤。 控制器基于由剂量测定模式产生的病变自动或响应于用户输入选择治疗束的剂量参数，从而通过选择由剂量学模式病变确定的病变的特征来实现期望的临床效果 。

公开(公告)号：EP2211802A2

公开(公告)日：2010-08-04

申请号：EP08843434.5

申请日：2008-10-31

申请人： Lensx Lasers, Inc.

发明人： KURTZ, Ronald M.

IPC分类号： A61F9/008 ,  A61F9/007 ,  A61B18/20

CPC分类号： A61F9/00827 ,  A61B2090/3937 ,  A61B2090/3983 ,  A61F9/008 ,  A61F9/00825 ,  A61F2009/00846 ,  A61F2009/00851 ,  A61F2009/00855 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/0088 ,  A61F2009/00882 ,  A61F2009/00897

摘要： Techniques, systems are described for performing laser eye surgery. In one aspect, a method for improving an optical function of an eye includes preparing the eye for surgery by determining an optical characteristic of the eye. Laser marking pulses are applied to generate a laser mark in a region of the eye in relation to the determined optical characteristic. Also, a surgical procedure is performed in a surgical region selected in relation to the generated laser mark.

公开(公告)号：EP0697611A2

公开(公告)日：1996-02-21

申请号：EP95109894.6

申请日：1995-06-24

申请人： Carl Zeiss ,  CARL-ZEISS-STIFTUNG, HANDELND ALS CARL ZEISS

发明人： Wei, Jay ,  Hellmuth, Thomas, Dr.

IPC分类号： G02B21/24 ,  A61B3/107

CPC分类号： G02B21/0012 ,  A61B3/102 ,  A61B3/13 ,  A61B18/20 ,  A61B2018/00636 ,  A61F9/008 ,  A61F9/00802 ,  A61F9/00821 ,  A61F2009/00851 ,  A61F2009/00853 ,  A61F2009/00863 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00887 ,  G01B9/02002 ,  G01B9/0203 ,  G01B9/02089 ,  G01B9/02091

摘要： Ophthalmologic surgical microscope which is combined internally with an optical coherence tomography ("OCT") apparatus wherein auto-focusing is provided by driving a motorized internal focusing lens of the ophthalmologic surgical microscope with a signal output from the OCT apparatus. An embodiment of the inventive ophthalmologic surgical microscope includes: (a) an optical coherence tomography ("OCT") apparatus; (b) a beamcombiner for internally coupling output from the OCT apparatus into the ophthalmologic surgical microscope; and (c) a motor for moving an internal focusing lens of the ophthalmologic surgical microscope in response to a signal from the OCT apparatus, whereby the ophthalmologic surgical microscope is auto-focused.

摘要翻译： 眼科手术显微镜在内部与光学相干断层扫描（“OCT”）装置组合，其中通过用从OCT装置输出的信号驱动眼科手术显微镜的机动化内部聚焦透镜来提供自动聚焦。 本发明的眼科手术显微镜的一个实施例包括：（a）光学相干断层扫描（“OCT”）装置; （b）用于将来自OCT装置的输出内部耦合到眼科手术显微镜中的光束组合器; （c）用于响应来自OCT设备的信号移动眼科手术显微镜的内部聚焦透镜的电动机，由此使眼科手术显微镜自动聚焦。

公开(公告)号：EP3362017A1

公开(公告)日：2018-08-22

申请号：EP16727846.4

申请日：2016-06-01

申请人： Novartis AG

发明人： SEILER, Theo ,  DONITZKY, Christof ,  RIEDEL, Peter ,  KLENKE, Jörg

IPC分类号： A61F9/008 ,  A61B3/10

CPC分类号： A61F9/0084 ,  A61B3/1005 ,  A61B3/1015 ,  A61B3/102 ,  A61F9/008 ,  A61F9/00827 ,  A61F9/00836 ,  A61F9/009 ,  A61F2009/00842 ,  A61F2009/00851 ,  A61F2009/00872

摘要： According to certain embodiments, a method for laser cutting treatment of a human eye comprises: determining position information of a pupil center of the eye in relation to a point of minimal corneal thickness in an undeformed state of the eye; locating the point of minimal corneal thickness in a flattened state of the eye, in which the eye is deformed by contact with a patient adapter of a laser device; and aligning a pulse firing pattern for laser radiation pulses of the laser device, based on a position of the located point of minimal corneal thickness and the determined position information. In embodiments, the pulse firing pattern represents, for example, a lenticular or doughnut-shaped intracorneal tissue volume which is to be removed from the cornea of the eye.

公开(公告)号：EP3319538A1

公开(公告)日：2018-05-16

申请号：EP16858413.4

申请日：2016-10-23

申请人： The Trustees of Columbia University in the City of New York

发明人： VUKELIC, Sinisa ,  TROKEL, Stephen

IPC分类号： A61B18/20 ,  A61F2/16 ,  A61F9/008 ,  A61F9/01 ,  A61N1/44

CPC分类号： A61F9/008 ,  A61B18/042 ,  A61B18/203 ,  A61B18/26 ,  A61B90/361 ,  A61B2018/00702 ,  A61B2018/00785 ,  A61B2018/00791 ,  A61B2018/20359 ,  A61B2018/20553 ,  A61B2018/205545 ,  A61B2018/263 ,  A61F2009/00851 ,  A61F2009/00872 ,  A61F2009/00882 ,  A61F2009/00897 ,  A61N1/44 ,  A61N5/062 ,  A61N2005/067

摘要： The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage or cornea, without using a photosensitizer (e.g., riboflavin), by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of tissue. In an embodiment, the femtosecond laser operates in the infrared frequency range.

公开(公告)号：EP3319503A1

公开(公告)日：2018-05-16

申请号：EP15828581.7

申请日：2015-12-15

申请人： Optimedica Corporation

发明人： GONZALEZ, Javier

IPC分类号： A61B3/10 ,  G06T7/00

CPC分类号： A61B3/0025 ,  A61B3/0033 ,  A61B3/0041 ,  A61B3/1005 ,  A61B3/102 ,  A61B3/1025 ,  A61B3/14 ,  A61F9/0084 ,  A61F2009/00846 ,  A61F2009/00851 ,  A61F2009/00889 ,  G06T7/11 ,  G06T7/162 ,  G06T2207/10101 ,  G06T2207/30041

摘要： A method of imaging an object includes obtaining an image data set from a raster scan. The image data set has a plurality of data points, each data point having an associated location and intensity; generating a reduced data set by selectively removing one or more data points from the image data set based upon an assigned probability of retaining the one or more data points in the data set, the assigned probability being a function of the intensity of a data point; generating a triangulation graph as a planar subdivision having faces that are triangles, the vertices of which are the data points and the edges of which are adjacent vertices; and segmenting the triangulated data set by finding a path with lowest cost between that vertex and every other vertex, wherein the cost is a function of the respective intensity of the vertices.

公开(公告)号：EP2775973B1

公开(公告)日：2018-05-09

申请号：EP11782067.0

申请日：2011-11-10

申请人： WaveLight GmbH

发明人： DONITZKY, Christof ,  KLENKE, Jörg

IPC分类号： A61F9/008

CPC分类号： A61F9/00836 ,  A61F2009/00851

摘要： In certain embodiments, a device configured to perform epithelial removal comprises a laser device and a control computer. The laser device can separate the epithelium from the Bowman's layer of an eye using pulsed laser radiation having ultrashort pulses. The laser device includes controllable components that control a focus of the pulsed laser radiation. The control computer controls the controllable components to focus the pulsed laser radiation at one or more epithelial cell layers of the epithelium to photodisrupt at least a portion of the epithelial cell layers.

公开(公告)号：EP3192478A4

公开(公告)日：2018-05-02

申请号：EP15828054

申请日：2015-07-30

申请人： LUTRONIC CORP

发明人： KIM JONG MIN

IPC分类号： A61F9/00 ,  A61F9/008 ,  A61N5/06

CPC分类号： A61F9/008 ,  A61F9/00 ,  A61F9/00821 ,  A61F2009/00844 ,  A61F2009/00851 ,  A61F2009/00863 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00897 ,  A61N5/06 ,  A61N5/0616

摘要： The present invention relates to an ophthalmic treatment device and a method for operating the same. The present invention provides an ophthalmic treatment device and a method for operating the same, the ophthalmic treatment device comprising: a treatment beam generation unit for generating a treatment beam; a beam delivery unit for forming a path along which the treatment beam generated from the treatment generation unit is delivered to a treatment area positioned on the fundus; a monitoring unit for emitting a detecting beam along the path of delivery of the treatment beam and sensing treatment area state information on the basis of information regarding a change in speckle of the detecting beam, which is scattered and reflected from the treatment area; and a control unit for controlling the driving of the treatment beam generation unit on the basis of the treatment area state information sensed by the monitoring unit.

公开(公告)号：EP2468225B1

公开(公告)日：2018-02-21

申请号：EP11195249.5

申请日：2011-12-22

申请人： Nidek Co., Ltd.

发明人： Yamamoto, Mitsuo

IPC分类号： A61F9/008 ,  A61B3/12 ,  A61B3/10

CPC分类号： A61F9/00821 ,  A61F2009/00851 ,  A61F2009/00863

摘要： An ophthalmic laser treatment apparatus includes an irradiation position obtaining unit (70,57,76) arranged to obtain analysis result data based on a tomographic image of a patient's fundus captured by an optical coherence tomography device (10) before a treatment laser beam is irradiated, and obtain information of an irradiation position of the treatment laser beam with respect to the fundus set by use of the obtained analysis result data, and a laser control unit (70) arranged to irradiate the laser beam to the fundus of an eye based on the irradiation position information obtained by the irradiation position obtaining unit.

公开(公告)号：EP3131457A4

公开(公告)日：2017-11-29

申请号：EP15825412

申请日：2015-07-14

申请人： NOVARTIS AG

发明人： YU LINGFENG ,  REN HUGANG

IPC分类号： A61B3/10 ,  A61B3/113 ,  A61B5/00 ,  A61B17/00 ,  A61B34/00 ,  A61B34/20 ,  A61B90/00 ,  A61F9/007 ,  A61F9/008

CPC分类号： A61F9/007 ,  A61B3/102 ,  A61B3/113 ,  A61B5/6886 ,  A61B17/00234 ,  A61B34/20 ,  A61B34/75 ,  A61B2034/2055 ,  A61B2090/3735 ,  A61F9/008 ,  A61F2009/00851

摘要： An OCT-augmented surgical instrument able to correct for undesired movement, as well as a system for use with such a surgical instrument and a method of correcting for undesired movement during surgery using OCT.