公开(公告)号：EP1562604B1

公开(公告)日：2012-01-04

申请号：EP03758747.4

申请日：2003-10-22

申请人： Sucampo AG

发明人： UENO, Ryuji

IPC分类号： A61K31/5575 ,  A61P3/04

CPC分类号： A61K31/557 ,  A61K31/5575 ,  Y10S514/909

摘要： Provided is a composition for treating obesity which comprises an effective amount of a prostaglandin compound, especially, a compound of formula (I).

公开(公告)号：EP2332545A1

公开(公告)日：2011-06-15

申请号：EP11155203.0

申请日：2006-01-26

申请人： Sucampo AG

发明人： Ueno, Ryuji

IPC分类号： A61K31/5575 ,  A61P25/00 ,  A61P25/16 ,  A61P25/28

CPC分类号： C07C405/00 ,  A61K31/557

摘要： The present invention provides a method and composition for treating a central nervous system disorder in a mammalian subject, which comprises administering an effective amount of a 11-deoxy-prostaglandin compound to a subject in need thereof. The invention also provide novel 11-deoxy-prostaglandin compound.

摘要翻译： 本发明提供用于治疗哺乳动物受试者的中枢神经系统疾病的方法和组合物，其包括向有需要的受试者施用有效量的11-脱氧 - 前列腺素化合物。 本发明还提供新的11-脱氧前列腺素化合物。

公开(公告)号：EP2329825A1

公开(公告)日：2011-06-08

申请号：EP11153504.3

申请日：2006-03-03

申请人： Sucampo AG

发明人： Ueno, Ryuji

IPC分类号： A61K31/5575 ,  A61P9/02 ,  A61P9/10

CPC分类号： A61K31/5575 ,  A61K31/557

摘要： The present invention provides a method for treating peripheral vascular diseases in a mammalian subject, which comprises administering to the patient in need thereof an effective amount of 11-deoxy-prostaglandin compound.

摘要翻译： 本发明提供了一种用于治疗哺乳动物受试者的外周血管疾病的方法，其包括向有需要的患者施用有效量的11-脱氧前列腺素化合物。

公开(公告)号：EP2327398A2

公开(公告)日：2011-06-01

申请号：EP11158821.6

申请日：2008-07-16

申请人： R-Tech Ueno, Ltd. ,  Sucampo AG

发明人： Harada, Yasuhiro ,  Kawasaki, Junichi ,  Nishimura, Yoshie ,  Ueno, Ryuji

IPC分类号： A61K9/48 ,  A61K31/5575

CPC分类号： A61K47/14 ,  A61K9/4858 ,  A61K31/5575

摘要： Provided is a pharmaceutical composition comprising a 11-deoxy-prostaglandin compound represented by formula (I): and a fatty acid ester. By mixing the compound of formula (I) and a fatty acid ester, the compound of formula (I) will be stabilized.

摘要翻译： 提供了一种包含由式（I）表示的11-脱氧 - 前列腺素化合物的药物组合物：和脂肪酸酯。 由式（I）的化合物和脂肪酸酯，式（I）的化合物混合将被稳定化。

公开(公告)号：EP2303278A1

公开(公告)日：2011-04-06

申请号：EP09712320.2

申请日：2009-02-19

申请人： Sucampo AG

发明人： UENO, Ryuji ,  KUNO, Sachiko

IPC分类号： A61K31/5575 ,  A61P43/00 ,  A61P19/08 ,  A61P19/10 ,  A61P7/06 ,  A61P21/00

CPC分类号： C07C53/134 ,  A61K31/5575

摘要： In one embodiment, provided is a composition comprising a prostaglandin compound for modulating stem cell proliferation and/or differentiation in a mammalian subject. In another embodiment, the instant application is a composition comprising a prostaglandin compound for, which comprises a prostaglandin compound for modulating proliferation and/or differentiation of stem cells of a mammalian subject, in which the stem cells are contacted directly or indirectly with the composition of the invention.

公开(公告)号：EP1853271B1

公开(公告)日：2010-12-01

申请号：EP06715488.0

申请日：2006-03-03

申请人： Sucampo AG

发明人： UENO, Ryuji

IPC分类号： A61K31/5575 ,  A61P9/02 ,  A61P9/10

CPC分类号： A61K31/5575 ,  A61K31/557

摘要： The present invention provides a method for treating peripheral vascular diseases in a mammalian subject, which comprises administering to the patient in need thereof an effective amount of 11-deoxy-prostaglandin compound.

公开(公告)号：EP1267882B1

公开(公告)日：2009-04-15

申请号：EP01914192.8

申请日：2001-03-23

申请人： Sucampo AG

发明人： UENO, Ryuji ,  MASHIMA, Yukihiko

IPC分类号： A61K31/557 ,  A61P9/10 ,  A61P25/28 ,  A61P27/02 ,  A61P29/00 ,  A61P35/00 ,  A61P43/00

CPC分类号： A61K31/557 ,  A61K31/5575 ,  A61K31/558 ,  Y10S514/912

摘要： Disclosed is a new use of 15-keto-prostaglandin compound as an apoptosis inhibitor. Said compound can inhibit apoptosis effectively and is useful for treatment of a subject such as a human having a disease or condition associated with apoptosis.

公开(公告)号：EP1426361B1

公开(公告)日：2008-07-30

申请号：EP04005836.4

申请日：2000-10-13

申请人： Sucampo AG

发明人： Ueno, Ryuji ,  Habe, Tsuyoshi

IPC分类号： C07D221/04 ,  A61K31/352 ,  A61K47/12 ,  A61P11/08

CPC分类号： A61K9/4858 ,  A61K9/0048 ,  C07C69/738 ,  C07D311/94 ,  C07D333/78 ,  C07D335/04

公开(公告)号：EP1389116B1

公开(公告)日：2008-02-27

申请号：EP02771715.6

申请日：2002-05-17

申请人： Sucampo AG

发明人： UENO, Ryuji

IPC分类号： A61K31/557 ,  C07C405/00

CPC分类号： A61K31/5575 ,  C07C405/00

公开(公告)号：EP1841433A2

公开(公告)日：2007-10-10

申请号：EP06712847.0

申请日：2006-01-26

申请人： Sucampo AG

发明人： UENO, Ryuji

IPC分类号： A61K31/5575 ,  A61P25/00 ,  A61P25/16 ,  A61P25/28

CPC分类号： C07C405/00 ,  A61K31/557

摘要： The present invention provides a method and composition for treating a central nervous system disorder in a mammalian subject, which comprises administering an effective amount of a 11-deoxy-prostaglandin compound to a subject in need thereof. The invention also provide novel 11-deoxy-prostaglandin compound.