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公开(公告)号:EP3775288A1
公开(公告)日:2021-02-17
申请号:EP19721394.5
申请日:2019-04-10
申请人: Istituti Fisioterapici Ospitalieri , ISTITUTO NAZIONALE TUMORI IRCCS "FONDAZIONE G. PASCALE" , Universita' Degli Studi di Roma "La Sapienza"
IPC分类号: C12Q1/6886
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公开(公告)号:EP3770700A1
公开(公告)日:2021-01-27
申请号:EP20187622.4
申请日:2020-07-24
发明人: GIORLEO, Luca , METELLI, Alessandro
摘要: A method for manufacturing components having a light weight for achieving the mechanical movement of a hand-wound watch, comprising the steps of:
- designing the components so that a single component includes the functionalities and features of several components, so that the total number of components is smaller than the present mechanical movements;
- manufacturing the components with additive manufacturing technology so that a single component comprises several components already partially assembled together, so that the post-assembly step requires less time; and
- assembling together the aforesaid components obtained via additive manufacturing to obtain the mechanism of a hand-wound watch.-
公开(公告)号:EP3765454A1
公开(公告)日:2021-01-20
申请号:EP19711363.2
申请日:2019-03-18
发明人: BOTTA, Maurizio , CANDUCCI, Filippo , CAGNO, Valeria , LEMBO, David , TINTORI, Cristina , BRAI, Annalaura , PALOMBI, Nastasja
IPC分类号: C07D403/06 , C07D417/06 , A61P31/12 , A61K31/427 , A61K31/515
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公开(公告)号:EP3659736A1
公开(公告)日:2020-06-03
申请号:EP19211938.6
申请日:2019-11-27
摘要: A method to mechanically join two conductor materials with a different melting temperature. The method comprises, in succession:
- a contact step, during which a surface of a material with a higher melting temperature, where there are grooves, is arranged in contact with a surface of a material with a lower melting temperature, and
- a joining step, during which the two materials are subjected to a coupling pressure and, at the same time, are crossed through by a current at the plurality of grooves until the grooves are filled with said material with a lower melting temperature.;
said grooves having an undercut profile.-
公开(公告)号:EP3620452A1
公开(公告)日:2020-03-11
申请号:EP18193196.5
申请日:2018-09-07
IPC分类号: C07D215/233
摘要: The present invention relates to a process for the preparation of Lenvatinib of formula (I) from 4-amino-3-chloro-phenol and 4-chloro-7-methoxyquinoline-6-carboxamide.
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公开(公告)号:EP3614922A1
公开(公告)日:2020-03-04
申请号:EP18721865.6
申请日:2018-04-26
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公开(公告)号:EP3609983A1
公开(公告)日:2020-02-19
申请号:EP18735423.8
申请日:2018-04-04
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公开(公告)号:EP3608342A1
公开(公告)日:2020-02-12
申请号:EP19000360.8
申请日:2019-08-02
摘要: A method is proposed for producing cellulose nanocrystals (CNCs) comprising:
i. a step of feeding a cellulosic raw material, such as native vegetable fibres or vegetable biomass materials or by-products of the textile, milling industries, and of paper,
ii. a step of putting the cellulosic raw material in contact with an oxidative acid component at high temperature to produce cellulose nanocrystals (CNCs) and
iii. a step of recovery of the cellulose nanocrystals obtained,
in which method there is provided a hydrolytic-oxidative microwave-assisted treatment, with closed microwave reactor under pressurised conditions.
The nanocrystals obtained can advantageously form pourable suspensions, for example as a thin and functional cladding on the activated surface of flexible packaging materials.-
公开(公告)号:EP3141897B1
公开(公告)日:2020-02-12
申请号:EP16188167.7
申请日:2016-09-09
发明人: PULIGHEDDU, Sonia , SASSU, Lorenzo , MASILI, Alice
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