Verfahren zur Herstellung von Kristallen aus in Lösungsmitteln gelösten Feststoffen
    83.
    发明公开
    Verfahren zur Herstellung von Kristallen aus in Lösungsmitteln gelösten Feststoffen 有权
    维尔法赫恩·赫尔斯特隆·冯·克里斯塔伦(Aris)在LösungsmittelngelöstenFeststoffen

    公开(公告)号:EP1308193A1

    公开(公告)日:2003-05-07

    申请号:EP02022514.0

    申请日:2002-10-07

    IPC分类号: B01D9/02

    摘要: Es wird eine Verfahren zur Herstellung von regelmäßigen Kristallen aus in einem Lösungsmittel gelösten Feststoff vorgeschlagen, wobei je nach positiver oder negativer Löslichkeit des Feststoffes in dem jeweiligen Lösungsmittel die Lösung unter Bildung des Feststoffkristallisates bis unterhalb ihrer Sättigungstemperatur abgekühlt bzw. bis oberhalb ihrer Sättigungstemperatur erhitzt und das Feststoffkristallisat abgetrennt wird. Zur Erzeugung weitestgehend fehlstellenfreier Kristalle mit einer homogenen und engen Partikelgrößenverteilung wird die Lösung in einer laminaren Scherströmung (Couette-Strömung) abgekühlt bzw. erhitzt. Ferner wird eine Vorrichtung zur Durchführung eines solchen Verfahrens vorgeschlagen, welche einen zylindrischen Kristallisationsbehälter zur Aufnahme der Lösung und ein hierzu koaxial unter Bildung eines radialen Ringraums angeordnetes und relativ zu diesem rotierbares zylindrisches Innenteil umfaßt, wobei der Kristallisationsbehälter und/oder das Innenteil temperierbar sind.

    摘要翻译: 从具有溶解在溶剂中的正溶解度的固体制备晶体,包括在形成固体晶体的层流剪切流中将溶液冷却至低于其饱和温度; 并除去形成的固体晶体。 还包括用于生产晶体的装置的独立权利要求,该装置包括用于接收溶液的圆柱形容器(3),其中内部部件(4)同轴布置以形成环形室(7)。 容器和/或内部是温度控制的。

    Crystallization of alpha-L-aspartyl-L-phenylalanine methyl ester by vaporization of droplets of slurry through a layer of cold air
    84.
    发明公开
    Crystallization of alpha-L-aspartyl-L-phenylalanine methyl ester by vaporization of droplets of slurry through a layer of cold air 审中-公开
    通过Abschlämmungströpfchen的蒸发的α-L-天冬氨酰-L-苯丙氨酸的Crystallisierung通过冷气的层

    公开(公告)号:EP0978518A1

    公开(公告)日:2000-02-09

    申请号:EP98309953.2

    申请日:1998-12-04

    IPC分类号: C07K5/06 C30B7/00 C30B35/00

    摘要: Disclosed is a method of crystallizing α-L-aspartyl-L-phenylalanine methyl ester, which is a sweetening agent substituting sugar and commonly referred to as aspartame. An aspartame solution is sprayed and droplets of the solution fall downward. Cold airflow is blown to the falling droplets of the aspartame solution to cool them. The aspartame dissolved in the droplets crystallizes, and the slurry including the aspartame crystals and the remaining solution is collected for further processes. Also disclosed is a crystallizer for cooling crystallizing the aspartame solution with this method. The crystallizer has an atomizer for spraying the aspartame solution supplied thereto and an air inlet and an air outlet. The cold air is blown into the crystallizer through the air inlet, cools the droplets of the aspartame solution, and is discharged through air outlet.

    摘要翻译: 本发明公开了结晶化的方法的α-L-天冬氨酰基-L-苯丙氨酸甲酯,其全部是甜味剂代糖,并通过以通常称为阿斯巴甜。 向下到糖精溶液喷雾,并将该溶液箱子液滴。 冷的气流吹到糖精溶液的下落液滴冷却。 在液滴中溶解糖精结晶,并将该浆料包括糖精晶体和剩余溶液收集用于进一步处理。 所以圆盘游离缺失是用于冷却结晶化用这种方法糖精溶液结晶器。 结晶器具有雾化器来喷雾提供至其中并且在空气入口和空气出口的糖精溶液。 的冷空气通过空气入口吹入结晶器中,冷却糖精溶液的液滴,并且通过空气出口排出。

    Organic thin film controlled molecular epitaxy
    86.
    发明授权
    Organic thin film controlled molecular epitaxy 失效
    有机薄层由可调Molekularepitaxie。

    公开(公告)号:EP0352931B1

    公开(公告)日:1993-10-20

    申请号:EP89307012.8

    申请日:1989-07-11

    IPC分类号: C30B23/02 C30B29/54 C23C14/12

    摘要: A layered structure comprises in sequence a substrate, and coated on at least a portion of at least one surface of said substrate a first layer comprising a crystalline uniaxially oriented organic compound, and at least one additional layer comprising a crystalline uniaxially oriented organic compound which is epitaxially vapor deposited on said first layer. A method for providing the layered structure of the invention comprises the steps of (a) providing a substrate, (b) depositing and crystallographically uniaxially orienting a first organic (seed) layer onto the substrate, (c) depositing from the vapor phase at least one additional organic layer onto the oriented seed layer to provide a layered structure wherein the at least one additional layer is epitaxial with the seed layer. t

    Method for producing organic crystal
    89.
    发明公开
    Method for producing organic crystal 失效
    一种用于制造有机晶体和晶体生长细胞为它的方法。

    公开(公告)号:EP0368169A1

    公开(公告)日:1990-05-16

    申请号:EP89120399.4

    申请日:1989-11-03

    IPC分类号: C30B11/00 C30B29/54 C30B29/60

    摘要: A method for producing an organic crystal is disclosed. One embodiment comprises maintaining a capillary tube (2) containing a fused liquid (3) of an organic crystal material and having a fused liquid reservoir (31) at one end thereof at a temperature not less than the fusion point of the organic crystal material together with the fused liquid reservoir, reducing the temperature of the fused liquid in the fused liquid reservoir to precipitate seed crystals, and then slowly cooling the capillary tube successively from the end toward the other end to allow a single crystal to grow from the seed crystal in the capillary tube. Because of the large quantity of the fused liquid, a seed crystal can be formed and allowed to grow even from a fused liquid of an organic crystal material which hardly crystallizes in the form of a fused liquid. Another embodiment comprises charging a solution of an organic crystal material in a capillary tube under heat, rapidly reducing the temperature of one end of the capillary tube to precipitate polycrystals, and then slowly cooling the capillary tube successively from the end toward the other end to allow a single crystal to grow from the polycrystal as a seed crystal. A seed crystal grows from a solution of an organic crystal material under control of crystal form to obtain a single crystal which has no inversion symmetry center, is free from lattice defect or rearrangement, and less causative of a laser beam loss.

    摘要翻译: 一种用于在有机晶体制造方法的游离缺失盘。 一个实施例包括维护一个毛细管(2)含有稠合的液体(3)的有机晶体材料制成并且具有其在一定温度下在一端具有一个稠合的液体贮存器(31)不小于有机晶体材料的熔化点一起 与稠合的液体贮存器,降低了熔融液体的温度在熔融液贮存器,以沉淀晶种,然后缓慢地从朝向另一端的端部连续地冷却该毛细管以允许单个晶体从晶种中生长 毛细管。 因为熔融液体的量大,晶种可以被形成并允许其从其中几乎不结晶在熔融液体形式的有机晶体材料的稠合的液体甚至增长。 另一实施例包括充电的有机晶体材料的溶液在毛细管中的在加热条件下,迅速减小了毛细管的一个端部的温度,以沉淀多晶体,然后缓慢地从朝向另一端的端部连续地冷却该毛细管以允许 单晶以从多晶作为晶种生长。 将晶种从下晶体形式的控制,以获得单晶不具有反演对称性中心的有机晶体材料的溶液的增长,从晶格缺陷或重排,和激光束的损失少致病自由。