利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

386 条记录 (耗时 0.049 秒)

    GENE-MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYADIPIC ACID, -HYDROMUCONIC ACID AND/OR ADIPIC ACID, AND PRODUCTION METHOD FOR SAID CHEMICAL PRODUCTS
    85.
    发明公开
    GENE-MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYADIPIC ACID, -HYDROMUCONIC ACID AND/OR ADIPIC ACID, AND PRODUCTION METHOD FOR SAID CHEMICAL PRODUCTS 审中-公开

    公开(公告)号：EP3719121A1

    公开(公告)日：2020-10-07

    申请号：EP18883299.2

    申请日：2018-11-29

    申请人： Toray Industries, Inc.

    发明人： ISOBE, Kyohei ,  KAWAMURA, Kenji ,  YAMADA, Katsushige

    IPC分类号： C12N9/04 ,  C12N1/21 ,  C12P7/42 ,  C12P7/44 ,  C12N15/53

    摘要： Disclosed is a genetically modified microorganism into which a nucleic acid encoding an enzyme that catalyzes a reaction to reduce 3-oxoadipyl-CoA to 3-hydroxyadipyl-CoA is introduced. In the genetically modified microorganism, a nucleic acid encoding any one of the polypeptides described in (a) to (c) below is introduced or expression of the polypeptide is enhanced: (a) a polypeptide composed of an amino acid sequence represented by any one of SEQ ID NOs: 1 to 6 and 213, (b) a polypeptide composed of the same amino acid sequence as any one of the amino acid sequences, except that one or several amino acids are substituted, deleted, inserted, and/or added, and having enzymatic activity that catalyzes a reaction to reduce 3-oxoadipyl-CoA to 3-hydroxyadipyl-CoA, and (c) a polypeptide composed of an amino acid sequence with a sequence identity of not less than 70% to any one of the amino acid sequences and having activity to reduce 3-oxoadipyl-CoA to 3-hydroxyadipyl-CoA.

    PROCESS FOR ENZYMATIC OXIDATION OF LINEAR CARBOHYDRATES
    90.
    发明公开
    PROCESS FOR ENZYMATIC OXIDATION OF LINEAR CARBOHYDRATES 审中-公开

    公开(公告)号：EP3460067A1

    公开(公告)日：2019-03-27

    申请号：EP17192457.4

    申请日：2017-09-21

    申请人： Technische Universität München

    发明人： SIEBER, Volker ,  BEER, Barbara ,  PICK, André

    IPC分类号： C12P7/40 ,  C12P7/42 ,  C12P7/44 ,  C12P7/58 ,  C12P19/02 ,  C12P7/24 ,  C12N9/04

    摘要： A process for enzymatic oxidation of a terminal group of a linear carbohydrate is disclosed, wherein a carbohydrate of formula (I): TU-X-Y-TOG, wherein TU is a terminal unit selected from -CH 2 OH, -CHO, -COOH, and -C 1 -C 4 alkyl; X is a linear carbohydrate chain comprising 0 to 18 units [CR 1 R 2 ], wherein in each unit R 1 and R 2 independently can be hydrogen, hydroxyl, C 1 -C 4 alkyl, or can together form a keto group, Y is -CHOH, -CHNH 2 or -CHSH and TOG is an oxidzable terminal unit selected from -CH 2 OH and -CHO; is contacted with an NAD + dependent short chain dehydrogenase/reductase for oxidation of TOG.