METHODS OF MANUFACTURING BIOACTIVE GELS FROM EXTRACELLULAR MATRIX MATERIAL
    8.
    发明公开
    METHODS OF MANUFACTURING BIOACTIVE GELS FROM EXTRACELLULAR MATRIX MATERIAL 审中-公开
    VERFAHREN ZUR HERSTELLUNG VON BIOAKTIVEN GELEN AUSEXTRAZELLULÄREMMATRIXMATERIAL

    公开(公告)号:EP2953659A1

    公开(公告)日:2015-12-16

    申请号:EP14708706.8

    申请日:2014-02-07

    申请人: Acell, Inc.

    IPC分类号: A61L27/36 A61L27/52 A61L27/54

    摘要: The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.

    摘要翻译: 本发明涉及从ECM材料制备生物活性凝胶的方法,即保留生物活性的凝胶,并且可以用作临床前和临床组织工程和再生医学方法用于组织重建的支架。制造方法利用新的识别 来自ECM材料的生物活性凝胶可以通过在碱性环境中消化特定的ECM材料并中和以提供生物活性凝胶来产生。