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    ACELLULAR COLLAGENOUS TISSUE AND PROCESSING METHOD OF ARTIFICIAL VALVE COMPRISING ACELLULAR COLLAGENOUS TISSUE
    2.
    发明公开
    ACELLULAR COLLAGENOUS TISSUE AND PROCESSING METHOD OF ARTIFICIAL VALVE COMPRISING ACELLULAR COLLAGENOUS TISSUE 审中-公开

    公开(公告)号：EP3123860A4

    公开(公告)日：2017-10-25

    申请号：EP15767882

    申请日：2015-03-24

    申请人： KINGSTRONBIO (CHANGSHU) CO LTD

    发明人： ZHONG SHENGPING SAM ,  LIU JING

    IPC分类号： A01N1/00 ,  A61F2/24

    CPC分类号： A01N1/021 ,  A01N1/0215 ,  A61F2/2415 ,  A61F2/2427 ,  A61F2220/0075

    摘要： The present invention provides an acellular collagenous tissue and a method for processing an artificial heart valve containing the acellular collagenous tissue. The method comprises immersing the acellular collagenous tissue in a preservation liquid containing an ionic liquid until the size of the acellular collagenous tissue remains stable in a non-liquid environment. The present invention also provides a preservation method, comprising immersing the acellular collagenous tissue or the artificial heart valve containing acellular collagenous tissue in the preservation liquid containing ionic liquid until the size of the collagen tissue remains stable in the non-liquid environment, and after taking out the acellular collagenous tissue or the artificial heart valve containing the acellular collagenous tissue, removing the excessive preservation liquid adhered to a surface thereof , and packaging the acellular collagenous tissue or the artificial heart valve. The present invention also provides an acellular collagenous tissue and an artificial heart valve containing the acellular collagenous tissue processed by the method described above. The method provided by the present invention can effectively avoid a biological material damage caused by being in a non-liquid environment and is beneficial to implement a subsequent processing and sterilization for the biological material.

    ACELLULAR COLLAGENOUS TISSUE AND PROCESSING METHOD OF ARTIFICIAL VALVE COMPRISING ACELLULAR COLLAGENOUS TISSUE
    3.
    发明公开
    ACELLULAR COLLAGENOUS TISSUE AND PROCESSING METHOD OF ARTIFICIAL VALVE COMPRISING ACELLULAR COLLAGENOUS TISSUE 审中-公开
    AZELLULÄRESKOLLAGENGEWEBE UND VERARBEITUNGSVERFAHREN EINERKÜNSTLICHENKLAPPE MITAZELLULÄREMKOLLAGENGEWEBE

    公开(公告)号：EP3123860A1

    公开(公告)日：2017-02-01

    申请号：EP15767882.2

    申请日：2015-03-24

    申请人： Kingstronbio (Changshu) Co., Ltd.

    发明人： ZHONG, Shengping Sam ,  LIU, Jing

    IPC分类号： A01N1/00 ,  A61F2/24

    CPC分类号： A01N1/021 ,  A01N1/0215 ,  A61F2/2415 ,  A61F2/2427 ,  A61F2220/0075

    摘要： The present invention provides an acellular collagenous tissue and a method for processing an artificial heart valve containing the acellular collagenous tissue. The method comprises immersing the acellular collagenous tissue in a preservation liquid containing an ionic liquid until the size of the acellular collagenous tissue remains stable in a non-liquid environment. The present invention also provides a preservation method, comprising immersing the acellular collagenous tissue or the artificial heart valve containing acellular collagenous tissue in the preservation liquid containing ionic liquid until the size of the collagen tissue remains stable in the non-liquid environment, and after taking out the acellular collagenous tissue or the artificial heart valve containing the acellular collagenous tissue, removing the excessive preservation liquid adhered to a surface thereof , and packaging the acellular collagenous tissue or the artificial heart valve. The present invention also provides an acellular collagenous tissue and an artificial heart valve containing the acellular collagenous tissue processed by the method described above. The method provided by the present invention can effectively avoid a biological material damage caused by being in a non-liquid environment and is beneficial to implement a subsequent processing and sterilization for the biological material.

    摘要翻译： 本发明提供了一种无细胞胶原组织和用于处理含有无细胞胶原组织的人造心脏瓣膜的方法。 该方法包括将无细胞胶原组织浸入含有离子液体的保存液中，直到无细胞胶原组织的大小在非液体环境中保持稳定。 本发明还提供了一种保存方法，包括将含有无细胞胶原组织的无细胞胶原组织或人造心脏瓣膜浸入含有离子液体的保存液中，直到胶原组织的尺寸在非液体环境中保持稳定，并且在服用 脱离无细胞胶原组织或含有无细胞胶原组织的人造心脏瓣膜，去除附着在其表面上的过量保存液体，以及包封无细胞胶原组织或人造心脏瓣膜。 本发明还提供一种无细胞胶原组织和含有通过上述方法处理的无细胞胶原组织的人造心脏瓣膜。 本发明提供的方法可以有效地避免由于处于非液体环境而引起的生物材料损害，有利于实现生物材料的后续加工和灭菌。

    METHOD FOR PREPARING ARTIFICIAL HEART VALVE LEAFLETS
    7.
    发明公开
    METHOD FOR PREPARING ARTIFICIAL HEART VALVE LEAFLETS 审中-公开
    VERFAHREN ZUR HERSTELLUNGKÜNSTLICHERHERZKLAPPENSEGEL

    公开(公告)号：EP3090704A1

    公开(公告)日：2016-11-09

    申请号：EP14877472.2

    申请日：2014-03-24

    申请人： KINGSTRONBIO(CHANGSHU) CO., LTD

    发明人： ZHONG, Shengping Sam ,  JIN, Chang ,  LIU, Jing

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2415 ,  A61F2240/004 ,  A61L27/367 ,  A61L27/3687 ,  A61L27/3691 ,  A61L27/507 ,  A61L2430/20

    摘要： The present invention provides a method for preparing an artificial heart valve leaflet, comprising freezing an animal tissue membrane and processing the frozen animal tissue membrane so as to reach a preset thickness. The method, by processing the frozen animal tissue membrane, can conveniently obtain an artificial heart valve leaflet with a required thickness and increase the yield of the animal tissue membrane valve leaflet.

    摘要翻译： 本发明提供一种制备人造心脏瓣膜小叶的方法，包括冷冻动物组织膜并处理冷冻动物组织膜以达到预设厚度。 该方法通过加工冷冻动物组织膜，可以方便地获得具有所需厚度的人造心脏瓣膜小叶，并增加动物组织膜瓣膜小叶的产量。

    ARTIFICIAL HEART VALVE ANNULOPLASTY RING
    8.
    发明公开
    ARTIFICIAL HEART VALVE ANNULOPLASTY RING 审中-公开
    人造心脏瓣膜环

    公开(公告)号：EP3090703A1

    公开(公告)日：2016-11-09

    申请号：EP14877467.2

    申请日：2014-03-24

    申请人： KINGSTRONBIO(CHANGSHU) CO., LTD

    发明人： JIN, Chang ,  ZHONG, Shengping Sam

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2445 ,  A61F2/2448 ,  A61F2210/0076 ,  A61F2230/0091 ,  A61F2250/0015 ,  A61F2250/0018 ,  A61F2250/0029

    摘要： An artificial heart valve annuloplasty ring, including an outer layer (6) and an inner layer main body structure (8), the outer layer (6) is covered on the outside of the inner layer main body structure (8), and is used to be sutured to heart tissue. The inner layer main body structure (8) has a tubular helical structure formed by curling a sheet material strip, the tubular helical structure can adjust rigidity of the annuloplasty ring. The artificial heart valve annuloplasty ring has a simple structure, easily adjustable rigidity, and is easy to manufacture and process.

    摘要翻译： 一种人造心脏瓣膜瓣环成形术环，包括外层（6）和内层主体结构（8），外层（6）覆盖在内层主体结构（8）的外侧，用于 缝合到心脏组织。 内层主体结构（8）具有通过卷曲片材带而形成的管状螺旋结构，管状螺旋结构可以调节瓣环成形环的刚性。 该人造心瓣膜瓣环成形环结构简单，刚性可调，且易于制造和加工。