LIQUID-BASED CELL PRESERVATION SOLUTION AND PREPARATION METHOD THEREFOR

    公开(公告)号:EP4413857A1

    公开(公告)日:2024-08-14

    申请号:EP22717336.6

    申请日:2022-02-24

    Abstract: The present disclosure provides a liquid-based cell preservation solution and a method for preparing the same. The preservation solution includes, by mass percentage: 15 to 20% of an alcohol, 0.4 to 0.7% of a buffer component, 0.2 to 0.5% of an ionic strength modifying agent, 0.05 to 2% of an anticoagulant, 0.05 to 0.2% of a mucus dissociating agent, 0.5 to 0.9% of a preservative, and purified water as the balance. The components of cell preservation solution are set reasonably, and the cells may be preserved at normal temperature for a long time to maintain the cell morphology. Addition of the mucus dissociating agent may effectively soften cell mucus, and separates cells adhered by mucus in the sample, thereby preventing cell accumulation. Addition of the preservative may effectively inhibit the proliferation of mold, bacteria or other pathogens and facilitate cell preservation.

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