摘要:
The invention relates to an irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid such as a platelet suspension and/or plasma comprising : a casing 2, a support member 3 for carrying at least one irradiation bag containing the biological fluid, a light source 4 comprising two banks of light 5,6 disposed above and below the support member 3, and an agitating system 25 for moving the support member 3, the light source generating UVC light of suitable intensity to inactivate pathogens and/or leukocytes and the agitation system moving the support member in an orbital path with predetermined with predetermined amplitude and rotational frequency suitable to expose the whole biological fluid to UVC.
摘要:
The invention concerns a filtering unit for selectively eliminating a target substance from a biological fluid such as blood or a blood component, said unit comprising a filtering media (5) including, stacked from upstream to downstream: an upstream structure (6) for eliminating at least the target substance, said structure comprising a stack of layers (7) based on a nonwoven material having pores of diameter D, said structure further comprising, interposed between at least some of the layers (7) of the upstream structure, particles (8) of average diameter greater than diameter D, said particles (8) exhibiting an affinity for the target substance; a downstream structure (9) for retaining the particles (8) which consists of at least one layer (10) of porous material, the average diameter of the pores of said material being not greater than diameter D.
摘要:
The invention relates to an irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid such as a platelet suspension and/or plasma comprising: a casing (2), a support member (3) for carrying at least one irradiation bag (19) containing the biological fluid, a light source (4) comprising two banks of light (5, 6) disposed above and below the support member (3), and an agitating system (25) for moving the support member (3), the light source generating UVC light of suitable intensity to inactivate pathogens and/or leukocytes and the agitation system moving the support member in an orbital path with predetermined amplitude and rotational frequency suitable to expose the whole biological fluid to UVC.
摘要:
The invention relates to a receptacle designed for culture of cells including a first access channel (4) to the volume inside the receptacle, that is located on a transverse edge of the receptacle, the receptacle comprising a longitudinal folding line (7) along which the receptacle can be folded so as to form a first and a second compartment (8, 9) on each side of said folding line (7), the first compartment (8) being provided with a first longitudinal deflector (10) that is arranged to form a first confinement chamber (12) and a first nutrition chamber (13), said first chambers being in fluid communication and second compartment (9) being provided with a second longitudinal deflector (14) that is arranged to form a second confinement chamber (16) and a second nutrition chamber (17), said second chambers being in fluidic communication.
摘要:
The invention concerns a filtering unit for selectively eliminating a target substance from a biological fluid such as blood or a blood component, said unit comprising a filtering media (5) including, stacked from upstream to downstream: an upstream structure (6) for eliminating at least the target substance, said structure comprising a stack of layers (7) based on a nonwoven material having pores of diameter D, said structure further comprising, interposed between at least some of the layers (7) of the upstream structure, particles (8) of average diameter greater than diameter D, said particles (8) exhibiting an affinity for the target substance; a downstream structure (9) for retaining the particles (8) which consists of at least one layer (10) of porous material, the average diameter of the pores of said material being not greater than diameter D.
摘要:
The present invention relates to a blood bag system and a process for reducing pathogens and leucocytes in quantities of therapeutic platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.
摘要:
The present invention relates to a blood bag system and a process for reducing pathogens and leucocytes in quantities of therapeutic platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.