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公开(公告)号:EP4389889A2
公开(公告)日:2024-06-26
申请号:EP24170871.8
申请日:2018-10-09
发明人: Mandel, Gail , Adelman, John P. , Sinnamon, John
IPC分类号: C12N15/10
CPC分类号: C07K19/00 , C12N9/78 , C12N15/102 , A61P25/00 , A61P23/00 , C07K2319/0920130101 , C07K2319/8520130101 , C12N2310/1120130101 , C12N2310/53120130101
摘要: Compositions and methods for editing endogenous RNA molecules are provided.
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公开(公告)号:EP3585333B1
公开(公告)日:2023-07-19
申请号:EP18758148.3
申请日:2018-02-27
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公开(公告)号:EP3638814B8
公开(公告)日:2023-06-21
申请号:EP18733500.5
申请日:2018-06-05
发明人: STAUDT, Louis M. , STEIDL, Christian , MOTTOK, Anja , WRIGHT, George W. , SCOTT, David William , RIMSZA, Lisa M. , ROSENWALD, Andreas , GASCOYNE, Randy , GREINER, Timothy , WEISENBURGER, Dennis , SMELAND, Erlend B. , DELABIE, Jan , CAMPO GUERRI, Elias , OTT, German , BRAZIEL, Rita , JAFFE, Elaine S. , FU, Kai , CHAN, Wing C. , SONG, Joo , COOK, James R.
IPC分类号: C12Q1/6886
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公开(公告)号:EP3594359B1
公开(公告)日:2022-05-18
申请号:EP19170689.4
申请日:2014-11-05
发明人: STAUDT, Louis M. , WRIGHT, George W. , SCOTT, David William , CONNORS, Joseph M. , GASCOYNE, Randy D. , RIMSZA, Lisa , CAMPO GUERRI, Elias , GREINER, Timothy C. , COOK, James Robert , FU, Kai , WILLIAMS, Paul Michael , LIH, Chih-Jian , JAFFE, Elaine S. , BRAZIEL, Rita M. , ROSENWALD, Andreas , SMELAND, Erlend B. , CHAN, Wing C. , OTT, German , DELABIE, Jan , WEISENBURGER, Dennis , TUBBS, Raymond
IPC分类号: C12Q1/68
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公开(公告)号:EP3457851B1
公开(公告)日:2021-06-23
申请号:EP17800190.5
申请日:2017-05-18
发明人: SCANLAN, Thomas , DEVEREAUX, Jordan , PLACZEK, Andrew , BANERJI, Tapasree , FERRARA, Skylar , MEINIG, James Matthew , BANERJI, Tania
IPC分类号: C07C235/20 , C07C59/70 , A61K31/19 , A61P25/28
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公开(公告)号:EP3739054A1
公开(公告)日:2020-11-18
申请号:EP20155440.9
申请日:2011-05-16
IPC分类号: C12N15/869 , C12N15/33 , A61K39/12 , A61P31/12 , A61P35/00
摘要: Described Herein Are Recombinant Rhesus Cytomegalovirus (RhCMV) And Human Cytomegalovirus (HCMV) Vectors Encoding Heterologous Antigens, Such As Pathogen-Specific Antigens Or Tumor Antigens. The Recombinant Vectors Elicit And Maintain High Level Cellular And Humoral Immune Responses Specific For The Heterologous Antigen. The Recombinant RhCMV And HCMV Vectors May Be Used, For Example, For The Treatment Or Prevention Of Infectious Disease Or Cancer. In Some Examples, The Recombinant RhCMV Or HCMV Vectors May Include Deletions In Genes Encoding Immunomodulatory Proteins. In Some Examples, The Recombinant RhCMV Or HCMV Vectors May Be Deficient Or Impaired In Their Ability To Replicate Within A Cell, Disseminate Within The Host Or Spread Among Hosts By Including A Deletion In One Or More Genes Essential Or Augmenting For CMV Replication, Dissemination Or Spread.
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8.
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公开(公告)号:EP3506835A1
公开(公告)日:2019-07-10
申请号:EP17847654.5
申请日:2017-09-01
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