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公开(公告)号:EP3745444B1
公开(公告)日:2024-11-13
申请号:EP20167408.2
申请日:2020-03-31
发明人: BAILEY, Derek J.
IPC分类号: H01J49/00
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公开(公告)号:EP4323543B1
公开(公告)日:2024-10-30
申请号:EP23717368.7
申请日:2023-03-16
发明人: ROSS, Robert L. , DU, Min
IPC分类号: C12Q1/6806 , C12Q1/6809
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公开(公告)号:EP4413375A1
公开(公告)日:2024-08-14
申请号:EP22792915.5
申请日:2022-10-05
申请人: Thermo Finnigan LLC
发明人: REMES, Philip M.
CPC分类号: G01N33/6848 , G01N2458/1520130101 , H01J49/0031 , H01J49/0045
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公开(公告)号:EP4404239A2
公开(公告)日:2024-07-24
申请号:EP24179261.3
申请日:2021-03-30
申请人: Thermo Finnigan LLC
IPC分类号: H01J49/00
CPC分类号: G01N27/622 , H01J49/004
摘要: An ion mobility device includes a plurality of electrodes and a current source. The plurality of electrodes arranged along an axis extending from a first end to a second end. The plurality of electrodes configured to receive a gas flow at the second end and provide for an expansion of the gas flow from the second end to the first end such that a first gas velocity at the second end is greater than a second gas velocity at the first end. The current source is configured to apply a first potential to the plurality of electrodes to generate a first electric field during a trapping and equilibration time period; and apply a second potential to the electrodes during an ejection time period to generate a second electric field, the second electric field being greater than the first electric field.
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公开(公告)号:EP4394844A1
公开(公告)日:2024-07-03
申请号:EP23215747.9
申请日:2023-12-12
申请人: Thermo Finnigan LLC
CPC分类号: H01J49/062 , H01J49/4255 , H01J49/429
摘要: Disclosed herein are systems and methods for sorting ions including a group of multipole electrodes configured to form an ion trap, and an ion guide adjacent to, and operably coupled to the group of multipole electrodes. Using a radio frequency (RF) or Direct Current (CD) power supply device the system can apply an RF voltage to the group of multipole electrodes thereby creating a pseudo-potential barrier. A DC gradient voltage may then be applied creating an axial field in opposition to the pseudo-potential barrier. As the DC voltage is raised and/or the RF voltage is lowered, one or more ions will be eluted through the barrier.
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公开(公告)号:EP4362059A1
公开(公告)日:2024-05-01
申请号:EP23204424.8
申请日:2023-10-18
CPC分类号: H01J49/0027 , H01J49/004 , G01N30/72 , H01J49/04
摘要: A system for performing dynamic DIA directs a mass spectrometer to acquire, based on an acquisition schedule that schedules a plurality of acquisition cycles, MS2 spectra of product ions derived from analytes included in a sample as the analytes elute from a separation system. The acquisition schedule specifies, for each acquisition cycle included in the plurality of acquisition cycles, a dynamic precursor m/z range based on an expected elution time of the analytes. The product ions are produced from precursor ions isolated using an isolation window successively positioned throughout the dynamic precursor m/z range during each acquisition cycle. The system detects an elution time shift in the elution time of the analytes as the analytes elute and adjusts the acquisition schedule based on the detected elution time shift.
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公开(公告)号:EP3901628B1
公开(公告)日:2024-05-01
申请号:EP21169577.0
申请日:2021-04-21
CPC分类号: G01N30/8679 , G01N30/7233 , G01N2030/883120130101 , G01N30/8675 , G01N2458/1520130101
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公开(公告)号:EP3690436B1
公开(公告)日:2023-05-10
申请号:EP20152609.2
申请日:2020-01-20
发明人: MOHTASHEMI, Iman , KUMP, Matthew
IPC分类号: G01N30/86
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公开(公告)号:EP3340275B1
公开(公告)日:2021-11-03
申请号:EP17208210.9
申请日:2017-12-18
发明人: ZABROUSKOV, Vladimir
IPC分类号: H01J49/00
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