CRYSTALLINE FORM OF NICOTINAMIDE RIBOSIDE CHLORIDE

    公开(公告)号:EP3670522A1

    公开(公告)日:2020-06-24

    申请号:EP20153772.7

    申请日:2015-07-24

    IPC分类号: C07H19/04 A61K45/06

    摘要: Provided are crystalline forms of nicotinamide riboside, including a Form I of nicotinamide riboside chloride according to formula I

    Also disclosed are pharmaceutical compositions comprising the crystalline Form I of nicotinamide riboside chloride, and methods of producing such pharmaceutical compositions. In other aspects, the present disclosure pertains to methods comprising administering to a subject the crystalline Form I of nicotinamide riboside chloride. The present disclosure also provides methods of preparing the crystalline Form I of nicotinamide riboside chloride. Also provided are a crystalline Form I of nicotinamide riboside chloride that is prepared according to any of the disclosed methods for preparing the crystalline Form I.