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11 条记录 (耗时 0.012 秒)

    SYSTEM FOR EXPRESSION, PURIFICATION, AND DETECTION AND SCREENING OF BIOLOGICAL DRUGS
    1.
    发明公开
    SYSTEM FOR EXPRESSION, PURIFICATION, AND DETECTION AND SCREENING OF BIOLOGICAL DRUGS 审中-实审

    公开(公告)号：EP4379387A1

    公开(公告)日：2024-06-05

    申请号：EP22848447.3

    申请日：2022-07-22

    申请人： Innovel Intelligent Technology Co., Ltd. ,  Wuxi Biologics Ireland Limited

    发明人： CHEN, Hao ,  MA, Zhaoyuan ,  TAN, Kee Wee ,  ZHANG, Ying

    IPC分类号： G01N35/00 ,  G01N35/10 ,  G01N1/34

    CPC分类号： G01N35/00 ,  G01N35/10 ,  G01N1/34

    摘要： A system (10) for expression, purification, and detection and screening of biological drugs comprises: one or more incubators (1), which are used for culturing biological samples to provide basic samples for detection and screening of biological drugs; a liquid operation system (3), which is used for implementing predetermined operations on the biological samples cultured in the incubator(s) (1); a sample detection platform (5), which is used for detecting the biological samples so as to facilitate screening; a transfer platform, which is used for transferring the biological samples between the incubator(s) (1) and the liquid operation system (3) and/or between the liquid operation system (3) and the sample detection platform (5); and an automatic control system (6), which is configured to control the operation of at least one of the incubator(s) (1), the liquid operation system (3), the sample detection platform (5) and the transfer platform. The system (10) for expression, purification, and detection and screening of biological drugs not only increases by order of magnitude the throughput of expression, purification, and detection and screening of biological drugs while reducing by order of magnitude the number of operators, but also greatly increases the stability, uniformity and reproducibility of a process flow by means of standardized operations.

    INTELLIGENT GENE SYNTHESIS AND MONOCLONAL SELECTION SYSTEM
    3.
    发明公开
    INTELLIGENT GENE SYNTHESIS AND MONOCLONAL SELECTION SYSTEM 审中-实审

    公开(公告)号：EP4431590A1

    公开(公告)日：2024-09-18

    申请号：EP22892104.5

    申请日：2022-11-11

    申请人： Innovel Intelligent Technology Co., Ltd. ,  WuXi Biologics Ireland Limited

    发明人： CHEN, Hao ,  YANG, Kailin ,  ZHI, Yan ,  CHEN, Xiaoyue

    IPC分类号： C12M1/00 ,  C12M1/34 ,  G01N35/00

    CPC分类号： G01N35/00 ,  C12M1/34 ,  C12M1/00

    摘要： An intelligent system for gene synthesis and monoclonal picking, comprising: a core operation module for performing operations associated with gene synthesis and monoclonal picking; and a control system for controlling at least a part of operations of corresponding compartments of the core operation module. The core operation module at least includes: a liquid operation compartment for performing operations of mixing gene fragments and mixing synthetizing reagents with biological samples in the process of gene synthesis; a purification compartment for performing purification operations on nucleic acid products created after the mixing; an amplification compartment for performing amplification operations and error correction operations on fragments of the nucleic acid products and performing culturing and amplification operations on vectors; and a monoclonal picking compartment for performing monoclonal picking operations on purified and cultured nucleic acid products.