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公开(公告)号:EP3224352B1
公开(公告)日:2024-01-03
申请号:EP15801762.4
申请日:2015-11-25
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公开(公告)号:EP3897688B9
公开(公告)日:2023-10-04
申请号:EP19832342.0
申请日:2019-12-18
发明人: DONI, Andrea , MANTOVANI, Alberto
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公开(公告)号:EP3256461B1
公开(公告)日:2023-09-13
申请号:EP16707651.2
申请日:2016-02-12
发明人: MEYERHANS, Andreas , MARTINEZ DE LA SIERRA, Miguel-Angel , BRAI, Annalaura , FAZI, Roberta , TINTORI, Cristina , BOTTA, Maurizio , ARAQUE, José-Esté , MARTINEZ, Javier
IPC分类号: C07D401/12 , C07D405/12 , C07D249/04 , C07D249/06 , C07D257/04 , C07D271/06 , C07D271/10 , A61P31/12 , A61K31/4192 , A61K31/433 , A61K31/4245 , A61K31/41 , A61K31/4725 , A61K31/4439 , C07D261/08 , C07D285/12
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公开(公告)号:EP3419609B1
公开(公告)日:2023-04-26
申请号:EP17706788.1
申请日:2017-02-23
发明人: SANTUCCI, Annalisa , BERNARDINI, Giulia , LASCHI, Marcella , MANETTI, Fabrizio , PETRICCI, Elena
IPC分类号: A61K31/122 , A61K31/216 , A61K31/42 , A61P3/00
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公开(公告)号:EP4056347A1
公开(公告)日:2022-09-14
申请号:EP22160498.6
申请日:2022-03-07
申请人: Poltrona Frau S.P.A.
发明人: Maiolo, Giovanni
IPC分类号: B29C45/14 , B29C51/00 , B29C51/12 , B29C51/26 , B29C67/24 , B29C69/00 , B29C70/78 , B29K75/00 , B29K311/10 , B29K511/10 , B29K711/00 , B29K711/10
摘要: A method (100) for forming a natural fiber component (10), comprising providing (S101) a natural fiber initial element (11), placing (S102) the initial element (11) inside a first mold (12) and forming an intermediate product (13) by compression through thermoforming, extracting (S103) the intermediate product (13) from the first mold (12), fixing (S104) the intermediate product (13) to a second mold (14) and applying (S105) a mixture of polymeric material on a portion of the intermediate component (13) by means of an injection molding process to form at least one structure (15) attached to said portion, opening (S106) the second mold (14) and extracting (S107) the finished component (10), wherein a first surface (16) of the component (10) is completely made by thermoforming and a second surface (17) of the component (10) comprises the structure (15) made by injection molding.
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公开(公告)号:EP4040360A1
公开(公告)日:2022-08-10
申请号:EP21218420.4
申请日:2018-11-13
发明人: KWAK, Jung Ae , SONG, Sang Youp , PARK, In Jae
摘要: According to an exemplary embodiment of the present disclosure, a method of evaluating a patent using a structural equation includes the steps of: receiving an evaluation for an importance of a plurality of evaluation factors required to build an evaluation model for each of multiple predetermined evaluation indexes, from multiple experts, to evaluate a registered patent; verifying the evaluations of the plurality of experts for the importance of the individual evaluation factors; setting the verified evaluation factors as final evaluation factors; determining impact indexes of the set evaluation factors required to build an evaluation model for each evaluation index, using structural equation model analysis; generating an evaluation model for each evaluation index using the set evaluation factor, the set impact index, and a structural equation; obtaining patent information; and generating an evaluation result using the generated evaluation model and the obtained patent information for the patent to be evaluated.
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公开(公告)号:EP4039685A1
公开(公告)日:2022-08-10
申请号:EP21155769.9
申请日:2021-02-08
申请人: IRBM S.P.A. , C.N.C.C.S. S.c.a.r.l. Collezione Nazionale Dei Composti Chimici e Centro Screening
发明人: DI FABIO, Romano , PETROCCHI, Alessia , FERRANTE, Luca , GRILLO, Alessandro , SFERRAZZA, Alessio , MONTALBETTI, Christian , ROSSETTI, Ilaria , TORRENTE, Esther
IPC分类号: C07D409/14 , C07D401/14 , C07D417/14 , C07D487/04 , C07D519/00 , A61K31/497 , A61K31/4985 , A61P35/00 , A61P37/00
摘要: The present invention relates to new compounds capable of inhibiting the activity of SHP2 phosphatase, having the general Formula (I):
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公开(公告)号:EP3548610B1
公开(公告)日:2021-12-29
申请号:EP17803974.9
申请日:2017-11-29
发明人: BADAMI, Ester
IPC分类号: A61P35/00 , C12N5/0783
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公开(公告)号:EP3868396A1
公开(公告)日:2021-08-25
申请号:EP20158553.6
申请日:2020-02-20
申请人: Enthera S.R.L.
发明人: Amabile, Giovanni
IPC分类号: A61K39/00 , A61K38/17 , A61K39/395
摘要: The present invention relates to inhibitors of IGFBP5 and/or of at least one of its receptors, wherein said inhibitor has anti-fibrotic effect, methods for their production, pharmaceutical compositions containing said inhibitors, and uses thereof. In particular, the invention relates to antibodies or antigen binding fragments thereof that bind specifically to human IGFBP5 and/or to at least one of its receptors.
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公开(公告)号:EP2996733B1
公开(公告)日:2021-07-28
申请号:EP14725162.3
申请日:2014-05-19
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