公开(公告)号：EP4387622A1

公开(公告)日：2024-06-26

申请号：EP22843657.2

申请日：2022-12-20

申请人： Universitat de València ,  CECS ,  INSERM (Institut National de la Santé et de la Recherche Médicale) ,  Universite d'Evry Val d'Essonne ,  Università degli Studi di Torino ,  Fundacion para la Investigacion del Hospital Clinico de la Comunidad Valenciana

发明人： KONIECZNY, Piotr Tadeusz ,  ARTERO ALLEPUZ, Rubén Darío ,  JANUEL, Camille ,  MARTINAT, Cécile ,  BOIDO, Marina Maria ,  MENDUTI, Giovanna

IPC分类号： A61K31/4515 ,  A61K31/4709 ,  A61K31/519 ,  A61K31/7125 ,  A61P21/00 ,  A61K31/711

CPC分类号： A61K31/4515 ,  A61K31/7125 ,  A61K31/4709 ,  A61K31/519 ,  A61P21/00 ,  A61K31/711

公开(公告)号：EP3384007B1

公开(公告)日：2024-03-27

申请号：EP15909460.6

申请日：2015-11-30

发明人： DENG, Hongkui ,  ZHAO, Yang ,  ZHAO, Ting ,  GUAN, Jingyang ,  ZHANG, Xu ,  FU, Yao ,  YE, Junqing

IPC分类号： C12N5/071 ,  C12N5/074

公开(公告)号：EP3636773B1

公开(公告)日：2023-08-23

申请号：EP18836033.3

申请日：2018-07-13

发明人： PAZ-ARES RODRÍGUEZ, Luis ,  QUINTANAL VILLALONGA, Álvaro ,  FERRER SÁNCHEZ, Irene ,  MOLINA PINELO, Sonia ,  CARNERO MOYA, Amancio

IPC分类号： C12Q1/6886 ,  A61P35/00

公开(公告)号：EP4116326A1

公开(公告)日：2023-01-11

申请号：EP21779084.9

申请日：2021-03-30

申请人： Universidad de Murcia

发明人： CERÓN MADRIGAL, José Joaquín ,  MARTÍNEZ SUBIELA, Silvia ,  LÓPEZ ARJONA, Marina

IPC分类号： C07K16/26 ,  G01N33/74

摘要： The present invention relates to an in vitro method for the quantification of free oxytocin, protein-bound oxytocin that can be released in a reduction/alkylation treatment, and protein-bound oxytocin, in a sample, without performing a reduction/alkylation treatment, wherein said method comprising carrying out a first assay using a monoclonal antibody that binds specifically to free oxytocin and to protein-bound oxytocin that can be released in a reduction/alkylation treatment, and carrying out a second assay using a polyclonal antibody that binds specifically to protein-bound oxytocin. The invention also relates to the monoclonal antibody and polyclonal antibody, and to a composition and kit comprising same.

公开(公告)号：EP3960723A1

公开(公告)日：2022-03-02

申请号：EP20796214.3

申请日：2020-04-24

申请人： PROBELTE S.A.U.

发明人： MALO LÓPEZ-ROMÁN, Jorge ,  MENGUAL SOTO-NAVARRO, Carmen María ,  GARCÍA CARPENA, Juan José ,  CARRILLO GÓMEZ, Arturo Jesús ,  BOTELLA CAYUELAS, Alberto ,  BLANCA PICÓ, Isidro ,  CASANOVA BELMONTE, José Manuel ,  VÁZQUEZ FERNÁNDEZ, Guillermo

IPC分类号： C05F11/08

摘要： A liquid biofertiliser which comprises Azospirillum brasilense CECT 5802 and Pantoea dispersa CECT 5801 strains. A method for stimulating plant growth, which comprises applying said liquid biofertiliser to said plant. A method for obtaining a liquid biofertiliser, which comprises culturing said strains in first liquid culture mediums and adding the culture broths obtained to a second liquid culture medium.

公开(公告)号：EP3928081A1

公开(公告)日：2021-12-29

申请号：EP20771199.5

申请日：2020-06-19

申请人： Universitat D'Alacant / Universidad de Alicante

发明人： GRINDLAY LLEDÓ, Guillermo ,  GRAS GARCIA, Luis ,  MORA PASTOR, Juan ,  NAVAS GARC A, Marta

IPC分类号： G01N21/64 ,  G01N33/02 ,  G01N21/84 ,  G01N21/85 ,  G06T7/90

公开(公告)号：EP3922696A1

公开(公告)日：2021-12-15

申请号：EP20796436.2

申请日：2020-04-22

申请人： Central Techno Corporation

发明人： MIYAHARA Akira ,  HORIE Masaaki

IPC分类号： C09K11/06 ,  G01P13/00

摘要： [Problem] To provide: fluorescent particles that are used to create a fluorescent material for coating an object in the vicinity of a fluid, that move regularly in the fluid while suppressing halation generated by the objects, and that enable the motion/movement of the fluid to be sharply visualized; an inspection device; and an inspection method. [Solution] Substantially spherical fluorescent particles comprising a mixture containing at least one fluorescent material and a synthetic resin, wherein: the fluorescent material is excited by any purple visible light and UV rays having a wavelength of 290-405 nm, and emits visible light having a peak wavelength within the range of 410-620 nm; and the fluorescent particles have diameters of 100 nm to 1 mm and are distinguishable from bubbles and/or foreign bodies in the fluid when irradiated with the light.

公开(公告)号：EP3865513A1

公开(公告)日：2021-08-18

申请号：EP20382113.7

申请日：2020-02-17

申请人： FUNDACIÓN PARA LA INVESTIGACIÓN BIOMÉDICA DEL HOSPITAL 12 DE OCTUBRE ,  Fundación Cris de Investigación Para Vencer al Cáncer ,  Hospital Clínic de Barcelona ,  Institut D'Investigaciones Biomèdiques August Pi i Sunyer

发明人： ÁLVAREZ VALLINA, Luis Manuel ,  BLANCO DURANGO, Belén ,  JUAN OTERO, Manel

IPC分类号： C07K16/28 ,  A61P35/02

摘要： The present invention relates to a bispecific antibody comprising an anti-CD19 single-chain fragment variable and an anti-CD3 single-chain fragment variable. The present invention also relates to T cells secreting the bispecific antibody, method of preparation of T cells secreting the bispecific antibody and uses thereof in the treatment of a hematological malignancy selected from the group consisting of lymphoma, leukemia and myeloma.

公开(公告)号：EP3853859A1

公开(公告)日：2021-07-28

申请号：EP19795089.2

申请日：2019-10-11

申请人： Vivia Biotech, S.L.

发明人： GORROCHATEGUI GUILLEN, Julian ,  ROJAS RUDILLA, Jose Luis ,  BALLESTEROS NOBELL, Joan ,  VILLORIA MORILLO, Jesus ,  HERNANDEZ DEL CAMPO, Pilar ,  PRIMO RAMOS, Daniel ,  MARTINEZ LOPEZ, Joaquin ,  MONTESINOS FERNÁNDEZ, Pau ,  MARTÍNEZ CUADRÓN, David

IPC分类号： G16C20/30

公开(公告)号：EP3648794B1

公开(公告)日：2021-07-28

申请号：EP18740141.9

申请日：2018-07-03

发明人： MULLOR SANJOSÉ, José Luis ,  VÁZQUEZ MANRIQUE, Rafael ,  GONZÁLEZ FERNÁNDEZ, David

IPC分类号： A61K31/4709 ,  A61K33/26 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A61P25/00 ,  A61P25/28 ,  A61P3/08 ,  A61P3/00 ,  A61P31/14 ,  A61P31/18 ,  A61K45/06