-
-
公开(公告)号：EP3875582A1
公开(公告)日：2021-09-08
申请号：EP20305214.7
申请日：2020-03-02
申请人： URGO RECHERCHE INNOVATION ET DEVELOPPEMENT , Centre d'Etude des Cellules Souches (CECS) , Universite d'Evry Val d'Essonne
IPC分类号： C12N5/077
摘要： L'invention concerne un procédé de différenciation de cellules souches pluripotentes humaines en fibroblastes, caractérisé en ce que les cellules souches pluripotentes humaines sont cultivées sur un système adhérent en présence d'un milieu adapté à la culture des fibroblastes et en l'absence de cellules nourricières.
-
公开(公告)号：EP3875581A1
公开(公告)日：2021-09-08
申请号：EP20305218.8
申请日：2020-03-02
IPC分类号： C12N5/071
摘要： The present invention relates to ex vivo methods for obtaining populations of human keratinocytes derived from human pluripotent stem cells (hPSCs).
More particularly, the present invention relates to an automated method that combines in a sequential manner automated differentiation and amplification of a population of hPSC-derived keratinocytes.-
4.发明公开
公开(公告)号：EP3765595A1
公开(公告)日：2021-01-20
申请号：EP19716966.7
申请日：2019-03-12
-
公开(公告)号：EP4197536A1
公开(公告)日：2023-06-21
申请号：EP21383162.1
申请日：2021-12-20
申请人： Universitat de València , CECS , INSERM - Institut National de la Santé et de la Recherche Médicale , Universite d'Evry Val d'Essonne , Università Degli Studi Di Torino
发明人： Konieczny, Piotr Tadeusz , Artero Allepuz, Rubén Darío , Januel, Camille , Martinat, Cécile , Boido, Marina Maria , Menduti, Giovanna
IPC分类号： A61K31/4515 , A61K31/4709 , A61K31/519 , A61K31/7125 , A61P21/00 , A61K31/711
摘要： Haloperidol, or a pharmaceutically acceptable salt, ester or solvate thereof, as well as pharmaceutical compositions comprising the same, for use in methods for preventing and/or treating spinal muscular atrophy, are described.
-
公开(公告)号：EP4081220A1
公开(公告)日：2022-11-02
申请号：EP20841725.3
申请日：2020-12-26
申请人： Centre d'Etude des Cellules Souches (CECS) , Institut National de la Santé et de la Recherche Médicale , Genethon , Universite d'Evry Val d'Essonne
发明人： HOCH, Lucile , NISSAN, Xavier , RICHARD, Isabelle
IPC分类号： A61K31/4965 , A61K31/165 , A61K31/18 , A61K31/16 , A61K45/06
-
7.发明公开
公开(公告)号：EP3685846A1
公开(公告)日：2020-07-29
申请号：EP19305097.8
申请日：2019-01-24
申请人： Genethon , Centre d'Etude des Cellules Souches (CECS) , Institut National de la Santé et de la Recherche Médicale , Universite d'Evry Val d'Essonne
IPC分类号： A61K38/12 , A61K31/4709 , A61P21/00 , A61P17/06
摘要： The present invention relates to the use of a cyclic thiopeptide, advantageously thiostrepton or its derivatives, for treating a genetic disease linked to a conformational disorder of at least one protein, said disorder causing the cellular degradation of the protein.
-
公开(公告)号：EP4397751A1
公开(公告)日：2024-07-10
申请号：EP23305007.9
申请日：2023-01-04
IPC分类号： C12N5/071
CPC分类号： C12N5/0626 , C12N2506/0220130101 , C12N2506/4520130101 , C12N2533/9020130101 , C12N2533/5420130101 , C12N2501/12520130101 , C12N2501/15520130101 , C12N2501/36520130101 , C12N2501/41520130101 , C12N2501/72720130101
摘要： The present invention pertains to in vitro methods for obtaining a population of mature and functional human melanocytes from human pluripotent stem cells (hPSC) and to uses of said population. The method according to the present invention comprises a differentiation step wherein neural crest cells are cultured in presence of a GSK3 inhibitor such as CHIR99021 or WNT3A, BMP4, AA, SCF and EDN3.
-
公开(公告)号：EP4114475A1
公开(公告)日：2023-01-11
申请号：EP21714331.2
申请日：2021-03-02
-
-
-
-
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.008 秒)
