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公开(公告)号：EP0980389A1
公开(公告)日：2000-02-23
申请号：EP98901378.4
申请日：1998-01-26
发明人： CRIPPS, Allan, William,University of Canberra , KYD, Jannelle,University of Canberra , DUNKLEY, Margaret,Australian Inst. Mucosal Immun. , CLANCY, Robert, L.,Univ. of Newcastle
IPC分类号： C07K14/21 , A61K39/104 , G01N33/569
CPC分类号： C07K14/21 , A61K39/00 , Y10S435/975 , Y10S530/825
摘要： A novel antigen from P. aeruginosa is provided. The use of the antigen in detecting/diagnosing P. aeruginosa as well as its use in eliciting an immune response are also provided.
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公开(公告)号：EP0854728A1
公开(公告)日：1998-07-29
申请号：EP96928537.0
申请日：1996-08-22
IPC分类号： A61K39
CPC分类号： A61K39/12 , A61K39/102 , A61K2039/521 , A61K2039/525 , A61K2039/5252 , A61K2039/70 , C12N2760/16111 , C12N2760/16134
摘要： Vaccines useful in providing protection against lower respiratory tract infections are provided as well as methods of immunising a subject.
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公开(公告)号：EP0454735B1
公开(公告)日：1996-05-22
申请号：EP90902112.3
申请日：1990-01-19
发明人： HUSBAND, Alan, James
IPC分类号： A61K39/02 , A61K39/04 , A61K39/108 , A61K39/112 , A61K39/116 , A61K39/39
CPC分类号： A61K39/39 , A61K2039/5555 , A61K2039/55594
摘要： The present invention relates to a vaccine composition for intraperitoneal administration to stimulate IgA response, comprising an antigenically active substance in a vegetable oil vehicle, and optionally an adjuvant and in particular relates to a vaccine composition which stimulates a protective immune response against post weaning enteritis and enzootic pneumonia in pigs.
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公开(公告)号：EP0638175A1
公开(公告)日：1995-02-15
申请号：EP93911889.0
申请日：1993-04-29
CPC分类号： C12N1/04 , C07K14/205 , G01N33/56922 , G01N2333/205
摘要： Contemporary infection by Helicobacter pylori in a human or other mammal can be detected by detecting H. pylori-specific IgG antibody in saliva, or other mucous secretion, with an antigen preparation from H. pylori. Diagnosis depends on detection of the antigen-antibody complex. For improved reliability, the antigen preparation comprises H. pylori-derived components of about 265 kDa and about 340 kDa and is substantially free of an H. pylori-derived component of about 440 kDa. The antigen preparation may be immobilised onto a solid support such as a nitrocellulose strip.
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公开(公告)号：EP0779817A1
公开(公告)日：1997-06-25
申请号：EP95929986.0
申请日：1995-09-05
CPC分类号： A61K39/0002 , A61K39/002 , A61K39/05 , A61K39/095 , A61K2039/541
摘要： An enteral non-adjuvanted vaccine comprises a killed microorganism which infects the vagina. The microorganism may be a fungus, such as Candida albicans, a bacterium, such as Gardnerella vaginalis or Neisseria gonorrhoea, a protozoon, such as Trichomonas vaginalis, or a virus, such as Herpes genitalis. The absence of adjuvant gives a significant improvement in clearance of the microorganisms, compared to adjuvanted compositions.
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公开(公告)号：EP0486543A4
公开(公告)日：1992-08-05
申请号：EP90911890
申请日：1990-08-09
申请人： THE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION , AUSPHARM INTERNATIONAL LIMITED
摘要： Production of an electrosuspension of particles (5), comprising an insulating container (3) fitted with two spaced apart electrodes (2, 4) between which a high electrical potential is applied. At least one of the electrodes (2) is mounted for rotation by an associated electric motor (20). The electrode mounted for rotation preferably has a drum like configuration formed by a plurality of circumferentially spaced apart conductors (6). In a second aspect the invention produces an electrosuspension of micronised particles where one of the electrodes is in contact with a bed of particles and a second electrode is spaced above the particles. Field concentrating conductors are connected with the second electrode to generate ions and irradiate the surface of the particulate material with ions of opposite polarity to the first electrode.
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公开(公告)号：EP0638175B1
公开(公告)日：1998-06-17
申请号：EP93911889.9
申请日：1993-04-29
IPC分类号： G01N33/569 , C12N1/06
CPC分类号： C12N1/04 , C07K14/205 , G01N33/56922 , G01N2333/205
摘要： Contemporary infection by Helicobacter pylori in a human or other mammal can be detected by detecting H. pylori-specific IgG antibody in saliva, or other mucous secretion, with an antigen preparation from H. pylori. Diagnosis depends on detection of the antigen-antibody complex. For improved reliability, the antigen preparation comprises H. pylori-derived components of about 265 kDa and about 340 kDa and is substantially free of an H. pylori-derived component of about 440 kDa. The antigen preparation may be immobilised onto a solid support such as a nitrocellulose strip.
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公开(公告)号：EP0486543B1
公开(公告)日：1997-10-22
申请号：EP90911890.3
申请日：1990-08-09
摘要： Production of an electrosuspension of particles (5), comprising an insulating container (3) fitted with two spaced apart electrodes (2, 4) between which a high electrical potential is applied. At least one of the electrodes (2) is mounted for rotation by an associated electric motor (20). The electrode mounted for rotation preferably has a drum like configuration formed by a plurality of circumferentially spaced apart conductors (6). In a second aspect the invention produces an electrosuspension of micronised particles where one of the electrodes is in contact with a bed of particles and a second electrode is spaced above the particles. Field concentrating conductors are connected with the second electrode to generate ions and irradiate the surface of the particulate material with ions of opposite polarity to the first electrode.
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公开(公告)号：EP0486543A1
公开(公告)日：1992-05-27
申请号：EP90911890.0
申请日：1990-08-09
摘要： Afin de produire des électrosuspensions de particules (5), un conteneur isolant (3) est équipé d'au moins deux électrodes espacées (2, 4) entre lesquelles s'applique un potentiel électrique élevé. Au moins une des électrodes (2) est montée de façon à pouvoir être mise en rotation par un moteur électrique associé (20). L'électrode rotative, de préférence similaire à un tambour, est formée d'une pluralité de conducteurs (6) espacés dans le sens de la circonférence. Dans un deuxième aspect, une électrosuspension de particules micronisées est produite par une électrode en contact avec un lit de particules et par une deuxième électrode agencée au-dessus des particules. Des conducteurs concentrateurs de champ sont connectés à la deuxième électrode afin de générer des ions et d'irradier la surface des matériaux particulaires avec des ions ayant une polarité opposée à la première électrode.
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