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公开(公告)号：EP0638175A1
公开(公告)日：1995-02-15
申请号：EP93911889.0
申请日：1993-04-29
CPC分类号： C12N1/04 , C07K14/205 , G01N33/56922 , G01N2333/205
摘要： Contemporary infection by Helicobacter pylori in a human or other mammal can be detected by detecting H. pylori-specific IgG antibody in saliva, or other mucous secretion, with an antigen preparation from H. pylori. Diagnosis depends on detection of the antigen-antibody complex. For improved reliability, the antigen preparation comprises H. pylori-derived components of about 265 kDa and about 340 kDa and is substantially free of an H. pylori-derived component of about 440 kDa. The antigen preparation may be immobilised onto a solid support such as a nitrocellulose strip.
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公开(公告)号：EP0638175B1
公开(公告)日：1998-06-17
申请号：EP93911889.9
申请日：1993-04-29
IPC分类号： G01N33/569 , C12N1/06
CPC分类号： C12N1/04 , C07K14/205 , G01N33/56922 , G01N2333/205
摘要： Contemporary infection by Helicobacter pylori in a human or other mammal can be detected by detecting H. pylori-specific IgG antibody in saliva, or other mucous secretion, with an antigen preparation from H. pylori. Diagnosis depends on detection of the antigen-antibody complex. For improved reliability, the antigen preparation comprises H. pylori-derived components of about 265 kDa and about 340 kDa and is substantially free of an H. pylori-derived component of about 440 kDa. The antigen preparation may be immobilised onto a solid support such as a nitrocellulose strip.
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