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公开(公告)号：EP3062917A1
公开(公告)日：2016-09-07
申请号：EP14793257.8
申请日：2014-10-30
发明人： VINCENT, John , TOSTOES, Rui , VERAITCH, Farlan , DODGSON, John
CPC分类号： C12N5/0688 , A61K35/42 , B01D63/087 , B01D2313/10 , B01D2313/12 , B01D2315/14 , B01D2315/16 , C12M47/02 , G01N2001/4088
摘要： The present invention provides devices suitable for filtration including diafiltration of a suspension containing a species such as particles, cells or macromolecules, apparatus comprising such devices and methods of using the devices and apparatus. The devices of the invention comprise a vessel having a filter that divides the vessel into a first chamber and a second chamber provided with various outlet ports. Gas is used to finally concetrate the suspension (118) in the filtration chamber by displacing the liquid up to 95% through the filter (14).
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公开(公告)号：EP3062916A1
公开(公告)日：2016-09-07
申请号：EP14796853.1
申请日：2014-10-30
发明人： VINCENT, John , TOSTOES, Rui , VERAITCH, Farlan , DODGSON, John
CPC分类号： B01D63/08 , B01D63/06 , B01D2313/10 , B01D2313/12 , B01D2313/18 , B01D2313/32 , B01D2315/14 , B01D2315/16 , B01L3/502753 , C12M47/02 , C12N5/0602 , G01N2001/4088
摘要： The present invention provides devices, apparatus and systems suitable for achieving volume reduction in a liquid containing a species in suspension and methods of use thereof. The apparatus of the invention comprises (i) a filter device comprising: a tubular first chamber having a filter provided in a surface thereof, a second chamber in fluid communication with the first chamber through the filter, the device being provided with an inlet port opening to the first end of the first chamber, an outlet port opening to the second end of the first chamber, and a filtrate port opening to the second chamber, and (ii) a fluidic pathway from the outlet port, wherein the apparatus is configured to introduce the first liquid and a second fluid immiscible with the first to the first chamber and the apparatus comprises a flow cut-off means in the fluidic pathway from the outlet port.
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