摘要:
An apparatus and process for coating a plurality of articles in batches, in particular for applying a biocompatible layer on articles adapted to come into contact with blood or body tissue, e.g. a coagulation-preventing substance so as to render the articles non-thrombogenic. A plurality of article-carrying plates (14) are stacked upon one another and have a plurality of communicating wells (18) for receiving therein a respective article to be coated. A base plate (12) defines with a bottom side of a lowermost of said article-carrying plates a distribution chamber (34) for receiving and evenly distributing a solution containing a substance to be applied to said articles. The solution is fed through the wells of the stacked plates (14) in parallel vertical flows.
摘要:
There is described inter alia medical device having a surface which comprises a coating layer, said coating layer being a biocompatible composition comprising an entity capable of interacting with mammalian blood to prevent coagulation or thrombus formation, which entity is covalently attached to said surface through alink comprising a 1,2,3-triazole.
摘要:
The present invention relates to a composition comprising heparin to be used as a non-thrombogenic surface when in contact with arterial blood flow. It also relates to a device treated on the surface thereof with such a composition.
摘要:
The present invention relates to a composition comprising heparin to be used as a non-thrombogenic surface when in contact with arterial blood flow. It also relates to a device treated on the surface thereof with such a composition.
摘要:
A monoclonal antibody which has specificity towards an antigenic determinant of a saccharide having in reducing-terminal position a 2,5-anhydro hexose residue; a process for the preparation of such monoclonal antibody; a process for isolating saccharides; and a process for determining the presence of a saccharide.
摘要:
There is described inter alia a medical device having a surface which comprises a coating layer, the coating layer being a biocompatible composition comprising an anti-coagulant entity capable of interacting with mammalian blood to prevent coagulation or thrombus formation, which anti-coagulant entity is covalently attached to the surface through a linker comprising a thioether.
摘要:
An apparatus and process for coating a plurality of articles in batches, in particular for applying a biocompatible layer on articles adapted to come into contact with blood or body tissue, e.g. a coagulation-preventing substance so as to render the articles non-thrombogenic. A plurality of article-carrying plates (14) are stacked upon one another and have a plurality of communicating wells (18) for receiving therein a respective article to be coated. A base plate (12) defines with a bottom side of a lowermost of said article-carrying plates a distribution chamber (34) for receiving and evenly distributing a solution containing a substance to be applied to said articles. The solution is fed through the wells of the stacked plates (14) in parallel vertical flows.