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    DIFFERENTIAL DIAGNOSIS OF ECTOPIC CUSHING'S SYNDROME
    2.
    发明公开
    DIFFERENTIAL DIAGNOSIS OF ECTOPIC CUSHING'S SYNDROME 审中-公开

    公开(公告)号：EP3405101A1

    公开(公告)日：2018-11-28

    申请号：EP17741860.5

    申请日：2017-01-18

    申请人： Corcept Therapeutics, Inc.

    发明人： MORAITIS, Andreas G.

    IPC分类号： A61B5/00 ,  G01N33/74

    CPC分类号： G01N33/743 ,  A61B5/4227 ,  G01N33/74 ,  G01N2333/575 ,  G01N2333/723 ,  G01N2800/04 ,  G16H50/30

    摘要： Improved methods and systems for diagnosing and for treating Cushing's syndrome and Cushing's Disease are provided herein, including methods and systems for concurrently treating Cushing's syndrome and differentially diagnosing Cushing's Disease from Ectopic Cushing's Syndrome in a patient with an established diagnosis of ACTH-dependent Cushing's syndrome. Treatment methods can use glucocorticoid receptor antagonists (GRAs), which differentially affect the ratio of cortisol to ACTH levels in patients having Cushing's Disease versus patients having Ectopic Cushing's Syndrome. Methods for concurrently treating and differentially diagnosing Cushing's Disease from Ectopic Cushing's Syndrome include obtaining baseline cortisol and ACTH levels of a patient, treating the patient with a GRA according to a protocol that would typically substantially elevate cortisol levels, obtaining post-treatment cortisol and ACTH levels of the patient, determining a differential relationship between baseline cortisol and ACTH levels and post-treatment cortisol and ACTH levels and providing a positive diagnosis based on the differential relationship.

    SYSTEMS AND METHODS OF MANAGING TREATMENT OF A CHRONIC CONDITION BY SYMPTOM TRACKING
    5.
    发明公开
    SYSTEMS AND METHODS OF MANAGING TREATMENT OF A CHRONIC CONDITION BY SYMPTOM TRACKING 审中-公开
    系统和方法用于管理慢性疾病的治疗BY症状CHASE

    公开(公告)号：EP3143494A2

    公开(公告)日：2017-03-22

    申请号：EP15793415.9

    申请日：2015-05-18

    申请人： Corcept Therapeutics, Inc.

    发明人： LO, Steven ,  PENAKE, David ,  LYONS, John ,  SAGINIAN, Lisa

    IPC分类号： G06F7/06 ,  G06F17/40 ,  G06G7/60 ,  G06Q50/24

    CPC分类号： G16H15/00 ,  A61K31/567 ,  G01N33/492 ,  G06F19/00

    摘要： Devices, systems, and methods for use in managing treatment of a chronic disorder with pharmaceutical or therapeutic compounds by tracking symptoms associated with the disorder. Methods include inputting patient attributes, factors and various and other data relating to the patient in conjunction with one or more symptoms into a symptom tracking system and outputting a report of the data tracked over time to any of the patient, a medical professional and a drug developer to improve identification of a relapse of the chronic condition and improve management of the treatment regimen for any and all patients.

    摘要翻译： 设备，系统，以及用于与通过跟踪与该病症相关的症状的药物或治疗性化合物治疗管理慢性疾病的用途。 方法包括：输入病人属性，影响因素以及各种和其他数据涉及与一种或多种症状相结合病人进入一个症状跟踪系统和输出婷跟踪一段时间内任何病人的数据报告，医学专业的药物 开发商以改善慢性疾病的复发的识别，提高了治疗方案的管理的任何和所有的病人。

    SYSTEMS AND METHODS OF TREATMENT USING INTERVENTION AND TASKING DETERMINATION
    6.
    发明公开
    SYSTEMS AND METHODS OF TREATMENT USING INTERVENTION AND TASKING DETERMINATION 审中-公开
    百慕达麻醉药联合国麻醉药品联合会（AUFGABENBESTIMMUNG）

    公开(公告)号：EP3047450A1

    公开(公告)日：2016-07-27

    申请号：EP14846696.4

    申请日：2014-09-22

    申请人： Corcept Therapeutics, Inc.

    发明人： LO, Steven ,  PENAKE, David ,  LYONS, John ,  TULLY, Kate ,  WAIDNER, Katherine

    IPC分类号： G06Q50/00

    CPC分类号： G16H50/20 ,  A61B5/4833 ,  A61B5/4848 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/746 ,  A61B5/7465 ,  G06F19/00 ,  G06F19/328 ,  G06F19/345 ,  G16H10/60 ,  G16H40/20

    摘要： Devices, systems, and methods for use in managing patient treatments utilizing pharmaceutical or therapeutic compounds. Methods include accessing one or more fields of information relating to any of a patient, physician and drug treatment and relating the one or more fields, or combination thereof, to a particular attribute or outcome. By analyzing the one or more fields of data in relation to the attribute or outcome, the system determines suitability of an intervention(s) and tasks the intervention(s) to one or more entities to facilitate the desired attribute or outcome. In certain aspects, the system facilitates identification of complex relationships and trends between seemingly unrelated fields of information and outputs information for use in an intervention or various other purposes according to the attribute or outcome desired by the user.

    摘要翻译： 用于使用药物或治疗化合物管理患者治疗的装置，系统和方法。 方法包括访问与患者，医师和药物治疗中的任何一个相关的一个或多个信息领域，并将一个或多个领域或其组合与特定属性或结果相关联。 通过分析与属性或结果相关的一个或多个数据字段，系统确定干预的适用性，并将干预任务交给一个或多个实体以促进期望的属性或结果。 在某些方面，该系统有助于鉴别看似无关的信息领域之间的复杂关系和趋势，并根据用户期望的属性或结果输出用于干预或各种其他目的的信息。