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公开(公告)号:EP4462120A2
公开(公告)日:2024-11-13
申请号:EP24202895.9
申请日:2013-02-22
申请人: Children's Medical Center Corporation , The Technical University of Denmark , Dana-Farber Cancer Institute, Inc. , The Brigham and Women's Hospital Inc.
发明人: SILVER, Daniel , WANG, Zhigang , SZALLASI, Zoltan , RICHARDSON, Andrea , BIRKBAK, Nicolai Juul , EKLUND, Aron
IPC分类号: G01N33/50
摘要: The present invention is based, in part, on the identification of novel methods for defining predictive biomarkers of response to anti-cancer drugs.
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2.
公开(公告)号:EP4447972A2
公开(公告)日:2024-10-23
申请号:EP22908673.1
申请日:2022-12-14
IPC分类号: A61K31/519 , A61K31/5377 , A61P35/00 , A61P35/02
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公开(公告)号:EP4441227A2
公开(公告)日:2024-10-09
申请号:EP22902336.1
申请日:2022-11-29
IPC分类号: C12N15/113 , A61K48/00 , A61P35/00
CPC分类号: C12N15/907 , A61K31/34 , A61K31/198 , A61K31/573 , A61K33/243 , A61K31/7068 , A61K31/4439 , A61K31/727 , A61K31/137 , A61K45/06 , A61K38/05
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公开(公告)号:EP4440594A2
公开(公告)日:2024-10-09
申请号:EP22844332.1
申请日:2022-11-29
IPC分类号: A61K38/08 , A61K35/761 , A61K38/18 , A61K38/20 , A61P3/00 , A61P7/00 , A61P7/06 , C07K7/00 , G01N33/50 , A61P43/00
CPC分类号: A61K38/08 , A61K38/1816 , A61K38/206 , A61K35/761 , A61P7/06 , A61P7/00 , A61P3/00 , A61P43/00 , C07K7/06 , G01N33/5023 , C12Q1/6883 , C12Q2600/15620130101
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公开(公告)号:EP4436998A1
公开(公告)日:2024-10-02
申请号:EP22840432.3
申请日:2022-11-23
发明人: MARASCO, Wayne A. , CHANG, Matthew
CPC分类号: C07K16/2818 , C07K2317/3120130101 , C07K2317/7620130101 , A61P35/00 , C07K2317/9220130101
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公开(公告)号:EP4408819A1
公开(公告)日:2024-08-07
申请号:EP22877379.2
申请日:2022-09-30
发明人: MARTO, Jarrod , KIM, Justin , ADELMANT, Guillaume , KANG, Dahye
CPC分类号: C07D233/88 , C07D249/04 , C07D263/32 , C07D277/28 , C07D333/20 , C07D307/52 , C07D213/40 , C07C271/34
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7.
公开(公告)号:EP4405395A1
公开(公告)日:2024-07-31
申请号:EP22873890.2
申请日:2022-09-23
申请人: Dana-Farber Cancer Institute, Inc. , Beth Israel Deaconess Medical Center, Inc. , Yeda Research and Development Co. Ltd
发明人: KE, Shizhong , WULF, Gerburg , ZHOU, Xiao, Zhen , LONDON, Nir , WEI, Wenyi , LU, Kun, Ping , GRAY, Nathanael, S. , NABET, Behnam
CPC分类号: A61P35/04 , A61K45/06 , C12Y207/11022 , C12Y502/01008 , A61K31/519 , A61K31/506 , A61K31/203 , A61K33/36 , A61K2039/50520130101 , C07K16/2818 , C07K2317/7620130101
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8.
公开(公告)号:EP4399220A1
公开(公告)日:2024-07-17
申请号:EP22785887.5
申请日:2022-09-08
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公开(公告)号:EP4380919A1
公开(公告)日:2024-06-12
申请号:EP22854050.6
申请日:2022-08-01
发明人: JONES, Lyn Howard , CHE, Jianwei , HUANG, Huang , KONG, Nikki , FERRAO, Silas , LIU, Yingpeng , CRUITE, Justin
IPC分类号: C07C255/49 , A61K31/33 , C07C255/50 , C07D213/02 , A61K31/41
CPC分类号: A61K45/06 , C07D401/14 , C07D405/14 , C07D498/04 , C07D413/14 , A61P35/00
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公开(公告)号:EP4378957A2
公开(公告)日:2024-06-05
申请号:EP24154217.4
申请日:2016-07-28
发明人: DRANOFF, Glenn , FREEMAN, Gordon, James , SHARPE, Arlene, Helen , BLATTLER, Walter, A. , MATARAZA, Jennifer, Marie , SABATOS-PEYTON, Catherine, Anne , CHANG, Hwai, Wen , FREY, Gerhard, Johann
IPC分类号: C07K16/28
CPC分类号: A61K39/00 , A61K2039/50520130101 , C07K2317/2420130101 , C07K2317/7620130101 , C07K2317/9220130101 , C07K16/2818 , A61P35/00
摘要: Combination therapies comprising antibody molecules that specifically bind to PD-1 are disclosed. The combination therapies can be used to treat or prevent cancerous or infectious conditions and disorders.
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