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公开(公告)号：EP4074286A1
公开(公告)日：2022-10-19
申请号：EP22161294.8
申请日：2016-08-26
IPC分类号： A61F2/24
摘要： A valve prosthesis can be configured to be deployed within a native heart valve and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the native heart valve, a flap assembly positioned around an exterior of the expandable frame, a proximal end of the flap assembly being positioned at or proximate a proximal end of the expandable frame. In some embodiments, the flap assembly can extend outward from the frame and have an expanded configuration configured to create a barrier to fluid flow exterior to the frame when deployed within the native heart valve.
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公开(公告)号：EP3834777A1
公开(公告)日：2021-06-16
申请号：EP21150598.7
申请日：2016-08-26
发明人： COOPER, Alexander H. , LANDON, David Robert , SANCHEZ, Julio Cesar , RABITO, Glen T. , RATZ, J. Brent , QUADRI, Arshad , STEWART, Kevin M. , CHOW, Patrick
摘要： Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. A delivery component can have a plurality of slots that provide for desired bending of the delivery component, particularly compound bending of the delivery component that can facilitate steering of the delivery component in three dimensions.
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公开(公告)号：EP3586798A1
公开(公告)日：2020-01-01
申请号：EP19188415.4
申请日：2014-03-12
发明人： RATZ, J. Brent , QUADRI, Arshad , PESCE, Luca
IPC分类号： A61F2/24
摘要： A prosthesis (10) can comprise an expandable frame (20), a plurality of distal anchors (24) and a plurality of proximal anchors (22). The anchors can extend outwardly from the frame. The frame can be configured to radially expand and contract for deployment within a body cavity. The frame and anchors can have one of many different shapes and configurations. For example, when the frame is in an expanded configuration, the frame can have a larger cross-sectional dimension in a middle portion of the frame and a smaller cross-sectional dimension in a proximal portion and a distal portion of the frame, wherein the middle portion is between the proximal and distal portions. As another example, the anchors can have looped ends (48), the entire anchor may loop out from the frame.
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公开(公告)号：EP3459500A1
公开(公告)日：2019-03-27
申请号：EP18195912.3
申请日：2011-09-23
发明人： QUADRI, Arshad , RATZ, J. Brent
IPC分类号： A61F2/24
摘要： A replacement heart valve and method of treating valve insufficiency includes an expandable frame configured to engage a native valve annulus. A valve body is coupled to the frame. The valve body can include a leaflet portion and possibly a skirt portion. A portion of the frame has a foreshortening portion configured to longitudinally expand when urged to a radially compacted state and longitudinally contract when urged to a radially expanded state. In one embodiment the valve skirt is attached to the frame so that it can adapt to changes in the length of the frame. A delivery device in some embodiments can use one or more coverings, such as sheaths, to controllably release the replacement heart valve at a native heart valve.
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5.发明公开
公开(公告)号：EP3167847A1
公开(公告)日：2017-05-17
申请号：EP16202299.0
申请日：2006-11-09
发明人： QUADRI, Arshad
IPC分类号： A61F2/24
CPC分类号： A61F2/82 , A61F2/2418 , A61F2/915 , A61F2002/8483 , A61F2002/8486 , A61F2002/91541 , A61F2002/91558 , A61F2220/0016 , A61F2230/0013 , A61F2230/0054
摘要： A prosthetic heart valve comprising: an expandable stent comprising an array of diamonds when expanded, the array having a first row and a second row; a valve seated inside the expandable stent; a plurality of prongs extending inward from the first row; and a plurality of prongs extending inward from the second row, wherein prongs are pre-bent so that they are bent outwardly relative to a longitudinal axis of the expandable stent and are also bent inwardly relative to the longitudinal axis at a point offset from their free ends; wherein an increase in the diameter of the expandable stent results in a decrease in the length of the expandable stent to bring the prongs together to produce a connection to body tissue surrounding the stent.
摘要翻译： 一种假体心脏瓣膜，包括：可扩张支架，所述可扩张支架在扩张时包括钻石阵列，所述阵列具有第一排和第二排; 置于可扩张支架内的瓣膜; 从第一行向内延伸的多个叉; 以及多个从第二排向内延伸的叉状物，其中叉状物被预先弯曲，使得它们相对于可膨胀支架的纵向轴线向外弯曲，并且相对于纵向轴线在从其自由点偏离的点处也向内弯曲 结束; 其中可扩张支架的直径的增加导致可扩张支架的长度减小，以将叉头连接在一起以产生与围绕支架的身体组织的连接。
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公开(公告)号：EP2341871B1
公开(公告)日：2017-03-22
申请号：EP09737261.9
申请日：2009-10-01
发明人： QUADRI, Arshad , RATZ, Brent J.
CPC分类号： A61F2/246 , A61F2/2418 , A61F2/243 , A61F2/2439 , A61F2/95 , A61F2002/9505 , A61F2002/9511 , A61F2002/9517 , A61F2220/0075 , A61F2230/0054 , A61F2230/0067
摘要： A medical treatment system and method of treatment is described having an implant that can be positioned and deployed, then undeployed to allow repositioning of the implant. The system includes a self-expanding medical implant that longitudinally foreshortens upon radially expanding from a radially compacted state, a distal interface configured to attach the implant to a distal mount of a delivery device, and a proximal interface configured to attach the implant to a proximal mount of the delivery device. Moving the distal mount longitudinally away from the proximal mount applies a longitudinal tension to the implant causing the implant to expand longitudinally and contract radially, and moving the distal mount toward the proximal mount reduces a longitudinal tension in the implant allowing the implant to expand radially toward a fully expanded state.
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公开(公告)号：EP2901966B1
公开(公告)日：2016-06-29
申请号：EP15153122.5
申请日：2009-09-29
发明人： Quadri, Arshad , Ratz, J. Brent
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/24 , A61F2/2403 , A61F2/2409 , A61F2/2412 , A61F2/2415 , A61F2/848 , A61F2002/8483 , A61F2002/8486 , A61F2210/0076 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/0013 , A61F2230/0054 , Y10T29/49426
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公开(公告)号：EP3692950A1
公开(公告)日：2020-08-12
申请号：EP20154005.1
申请日：2016-08-26
IPC分类号： A61F2/24
摘要： A valve prosthesis can be configured to be deployed within a native heart valve and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the native heart valve, a flap assembly positioned around an exterior of the expandable frame, a proximal end of the flap assembly being positioned at or proximate a proximal end of the expandable frame. In some embodiments, the flap assembly can extend outward from the frame and have an expanded configuration configured to create a barrier to fluid flow exterior to the frame when deployed within the native heart valve.
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公开(公告)号：EP2367505B1
公开(公告)日：2020-08-12
申请号：EP09793152.1
申请日：2009-09-29
发明人： QUADRI, Arshad , RATZ, Brent, J.
IPC分类号： A61F2/24
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公开(公告)号：EP3505138A1
公开(公告)日：2019-07-03
申请号：EP18189143.3
申请日：2004-12-28
摘要： Methods and systems for endovascular, endocardiac, or endoluminal approaches to a patient's heart to perform surgical procedures that may be performed or used without requiring extracorporeal cardiopulmonary bypass. Furthermore, these procedures can be performed through a relatively small number of small incisions. These procedures may illustratively include heart valve implantation, heart valve repair, resection of a diseased heart valve, replacement of a heart valve, repair of a ventricular aneurysm, repair of an arrhythmia, repair of an aortic dissection, etc. Such minimally invasive procedures are preferably performed transapically (i.e., through the heart muscle at its left or right ventricular apex).
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