ANTIGENIC PEPTIDES FOR PREVENTION AND TREATMENT OF CANCER

    公开(公告)号:EP4169528A1

    公开(公告)日:2023-04-26

    申请号:EP22201142.1

    申请日:2019-04-11

    申请人: Enterome S.A.

    IPC分类号: A61K39/00 A61P35/00 C07K14/00

    摘要: The present invention relates to antigen-based immunotherapy, in particular cancer immunotherapy. In particular, the present invention provides antigenic peptides, which are distinct from, but have amino acid similarity to, fragments of human tumor antigens. The present invention further provides immunogenic compounds, nanoparticles, cells and pharmaceutical compositions comprising such antigenic peptides and nucleic acids encoding such antigenic peptides.

    IDENTIFICATION AND SYNTHESIS OF DRUG CANDIDATES DERIVED FROM HUMAN MICROBIOME METASECRETOME PROTEINS

    公开(公告)号:EP3855183A1

    公开(公告)日:2021-07-28

    申请号:EP20305060.4

    申请日:2020-01-24

    申请人: Enterome S.A.

    摘要: The present invention relates to the treatment of diseases relating to proteins of the human microbiome metasecretome and, thus, to microbiome interactions, especially microbiome-host interactions. In particular the present invention relates to a method for identification of secreted peptides and proteins of the human microbiome. The present invention also relates to methods for generating a database of human microbiome metasecretome protein sequences. Furthermore, the present invention relates to a method for preparing a protein of the human microbiome metasecretome as well as to the use of such proteins in medicine.