公开(公告)号：EP3502105A1

公开(公告)日：2019-06-26

申请号：EP17855006.7

申请日：2017-09-29

申请人： Betta Pharmaceuticals Co., Ltd. ,  Equinox Sciences, LLC.

发明人： LIANG, Congxin ,  XIE, Lihua

IPC分类号： C07D403/14 ,  A61K31/404 ,  A61P35/00

摘要： The invention discloses polymorphic forms of a compound of formula I, pharmaceutical compositions containing same, preparation method therefor and use thereof. The compound of formula I of the present invention is as shown in formula I, of which the crystalline form can be crystalline form 1, crystalline form 2, crystalline form 3, crystalline form 5, crystalline form 6 or crystalline form 7. All the crystalline forms of the compound of formula I in the present invention have good crystalline stability and chemical stability and a decrease in purity of their main ingredient less than 2%. The preparation method of the present invention may be used to produce the various crystalline forms of the compound of formula I with high purity, and suitable for large scale production.