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公开(公告)号：EP4166542A1
公开(公告)日：2023-04-19
申请号：EP21820923.7
申请日：2021-06-10
发明人： YANG, Rongwen , SUN, Yun , ZHANG, Jian , LIU, Xiangkai , WANG, Pingping , YI, Xuegang , MA, Teng , HUANG, Chuanlong , LAN, Hong , DING, Lieming , WANG, Jiabing
IPC分类号： C07D243/36 , A61K31/403 , A61P35/00
摘要： The present invention relates to compounds of formula (I). The present invention also provides compositions and formulations containing such compounds, and methods for using and preparing such compounds.
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公开(公告)号：EP4105207A1
公开(公告)日：2022-12-21
申请号：EP21754125.9
申请日：2021-02-08
发明人： LIU, Xiangyong , QIU, Changyong , LIU, Mengqiang , SONG, Xiaodong , SHEN, Qichao , DU, Guolong , SHENG, Haitong , DING, Lieming , WANG, Jiabing
IPC分类号： C07D401/12 , C07D471/10 , C07D487/00 , C07D241/02 , A61K31/66 , A61K31/675 , A61P35/00
摘要： The present invention relates to a compound of formula (I), a method for using the compound as an EGFR inhibitor, and a pharmaceutical composition comprising the compound. The compound can be used for treatment, prevention or alleviation of diseases or disorders such as cancer or infection.
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公开(公告)号：EP3559000A1
公开(公告)日：2019-10-30
申请号：EP17882916.4
申请日：2017-12-22
发明人： WANG, Yiqian , WANG, Jiabing , DING, Lieming
IPC分类号： C07D487/04 , C07D519/00 , A61K31/506 , A61K31/55 , A61P35/00 , A61P35/02
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公开(公告)号：EP2867223B1
公开(公告)日：2018-09-05
申请号：EP13809182.2
申请日：2013-07-01
发明人： HU, Shaojing , WANG, Fei , XU, Zhiguo , WANG, Yanping , WANG, Yinxiang
IPC分类号： C07D471/04 , C07D498/04 , C07D513/04 , A61K31/4353 , A61P35/00
CPC分类号： C07D471/04 , C07D498/04 , C07D513/04
摘要： This invention relates to novel fused quinazoline derivatives of Formula I as c-Met inhibitors, their synthesis and uses for treating c-Met mediated disorders.
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5.发明授权METHODS OF PREPARING ICOTINIB AND ICOTINIB HYDROCHLORIDE, AND INTERMEDIATES THEREOF 有权制备伊托替尼和盐酸伊托替尼的方法及其中间体
公开(公告)号：EP2796461B1
公开(公告)日：2017-09-06
申请号：EP12846055.7
申请日：2012-12-28
发明人： Hu, Shaojing , Long, Wei , Wang, Fei , Li, Zongquan
IPC分类号： C07D491/056 , A61K31/519 , C07D239/94
CPC分类号： C07D491/056 , C07D323/00 , C07D325/00 , C07D405/04
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公开(公告)号：EP2565205B1
公开(公告)日：2015-07-01
申请号：EP11774275.9
申请日：2011-04-29
发明人： WANG, Yinxiang , TAN, Fenlai , HU, Shaojing , ZHAO, Xiangdong , MA, Cunbo , WANG, Yanping , SHEN, Xiaoyan , DING, Lieming , HU, Yunyan , CAO, Hong , LONG, Wei
IPC分类号： C07K14/605 , A61K38/26 , A61P3/10
CPC分类号： C07K14/605 , A61K38/00
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7.发明公开NOVEL FUSED PYRIDINE DERIVATIVES USEFUL AS c-MET TYROSINE KINASE INHIBITORS 有权NOVEL合并吡啶AS C-MET酪氨酸激酶抑制剂
公开(公告)号：EP2867223A1
公开(公告)日：2015-05-06
申请号：EP13809182.2
申请日：2013-07-01
发明人： HU, Shaojing , WANG, Fei , XU, Zhiguo , WANG, Yanping , WANG, Yinxiang
IPC分类号： C07D401/14 , C07D401/12 , C07D487/02 , A61K31/4353 , A61P35/00
CPC分类号： C07D471/04 , C07D498/04 , C07D513/04
摘要： This invention relates to novel fused quinazoline derivatives of Formula I as c-Met inhibitors, their synthesis and uses for treating c-Met mediated disorders.
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8.发明公开POLYMORPHIC FORMS OF COMPOUNDS AS PROLYL HYDROXYLASE INHIBITOR, AND USES THEREOF 有权化合物的多晶形式如甲基羟丙基甲基纤维素酶抑制剂及其用途
公开(公告)号：EP2734504A4
公开(公告)日：2014-12-31
申请号：EP12817360
申请日：2012-07-23
发明人： KANG XINSHAN , LONG WEI , ZHANG JIANXI , HU YUNYAN , WANG YINXIANG
IPC分类号： C07D217/26 , A61K31/472 , A61P3/10 , A61P7/06 , A61P9/12 , A61P17/02 , A61P29/00 , A61P35/00 , A61P37/06 , A61P43/00
CPC分类号： C07D217/26 , A61K31/472 , C07B2200/13
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9.发明公开STABLE POLYMORPHIC FORMS OF COMPOUND AS HYPOXIA MIMETICS, AND USES THEREOF 审中-公开稳定多晶型形成了一个连接，HYPOXIEMIMETIKA及其用途
公开(公告)号：EP2736892A1
公开(公告)日：2014-06-04
申请号：EP12819230.9
申请日：2012-07-30
发明人： KANG, Xinshan , LONG, Wei , WANG, Fei , MA, Cunbo , ZHOU, Liufeng , HU, Yunyan , WANG, Yanping , CAO, Hong , WANG, Yinxiang , TAN, Fenlai
IPC分类号： C07D311/56 , A61K31/37 , A61P7/00
CPC分类号： C07D311/56
摘要： The polymorphic forms of the compound of Formula I, the preparation thereof including the preparation of the intermediates, the pharmaceutical compositions thereof and the uses of a polymorph above in the manufacture of medicaments for treating a disease, a disorder or a condition are disclosed.
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公开(公告)号：EP4196480A1
公开(公告)日：2023-06-21
申请号：EP21857661.9
申请日：2021-08-17
发明人： XU, Xiaofeng , GAO, Jinheng , RONG, Hongfei , SONG, Xizhen , CHEN, Jie , LIU, Xiangyong , SHEN, Hongling , GUO, Jing , YAN, Dan , LAN, Hong , DING, Lieming , WANG, Jiabing
IPC分类号： C07D487/00 , C07D487/04 , C07D491/052 , A61K31/395 , A61P35/00
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