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    CHEWING GUM COMPOSITION FOR USE IN ALLEVIATION OF XEROSTOMIA INDUCED BY RADIOTHERAPY TREATMENT
    4.
    发明公开
    CHEWING GUM COMPOSITION FOR USE IN ALLEVIATION OF XEROSTOMIA INDUCED BY RADIOTHERAPY TREATMENT 审中-公开
    口香糖组合物用于缓解由放射治疗引起的黄癣的作用

    公开(公告)号：EP3313383A1

    公开(公告)日：2018-05-02

    申请号：EP16733400.2

    申请日：2016-06-23

    申请人： Fertin Pharma A/S

    发明人： BRUUN, Heidi Ziegler

    IPC分类号： A61K9/68 ,  A61P1/02

    CPC分类号： A61K9/0058

    摘要： The invention relates to a chewing gum composition for use in the alleviation of xerostomia induced by radiotherapy treatment, where the chewing gum composition comprises gum base and substantially no flavour ingredients. Moreover, the invention also relates to a dosage regimen for administering the chewing gum composition for use in alleviation of xerostomia induced by radiotherapy treatment. So in one embodiment of the invention the chewing gum composition is administered to a human subject before and/or during and/or after radiotherapy treatment.

    ELECTRONIC NICOTINE DELIVERY SYSTEM
    5.
    发明公开
    ELECTRONIC NICOTINE DELIVERY SYSTEM 审中-公开
    电子尼古丁输送系统

    公开(公告)号：EP3200631A1

    公开(公告)日：2017-08-09

    申请号：EP14789515.5

    申请日：2014-10-03

    申请人： Fertin Pharma A/S

    发明人： NIELSEN, Bruno Provstgaard

    IPC分类号： A24F47/00

    CPC分类号： A24F47/008

    摘要： An electronic nicotine delivery system (ENDS) is disclosed, said electronic nicotine delivery system (ENDS) comprising a mouth piece (MP), an atomizer arrangement (AA), a power supply (PS), a nicotine container (NC), an additive container (AC), the atomizer arrangement (AA) comprising an inlet (NCI) from the nicotine container (NC) and an inlet (ACI) from the additive container (AC), the atomizer arrangement (AA) comprising two separate atomizers, a first atomizer (FA) and a second atomizer (SA), the first atomizer producing nicotine-containing aerosols having a first mass median aerodynamic diameter (FMMAD) and the second atomizer producing additive-containing aerosols having a second mass median aerodynamic diameter (SMMAD) and wherein the second mass median aerodynamic diameter (SMMAD) is greater than the first mass median aerodynamic diameter (FMMAD), the atomizers being electrically connected to the power supply (PS). Furthermore, a method of producing a mixture of aerosols, an aerosol mixture and a use of an electronic nicotine delivery system (ENDS) is disclosed.

    摘要翻译： 公开了一种电子尼古丁输送系统（ENDS），所述电子尼古丁输送系统（ENDS）包括口部件（MP），雾化器装置（AA），电源（PS），尼古丁容器（NC），添加剂 （AC），所述雾化器装置（AA）包括来自所述尼古丁容器（NC）的入口（NCI）和来自所述添加剂容器（AC）的入口（ACI），所述雾化器装置（AA）包括两个独立的雾化器， 第一雾化器（FA）和第二雾化器（SA），第一雾化器产生具有第一质量中值空气动力学直径（FMMAD）的含尼古丁的气溶胶，第二雾化器产生具有第二质量中值空气动力学直径（SMMAD）的含添加剂的气溶胶， 并且其中所述第二质量中值空气动力学直径（SMMAD）大于所述第一质量中值空气动力学直径（FMMAD），所述雾化器电连接到所述电源（PS）。 此外，公开了一种生产气溶胶混合物，气溶胶混合物和电子尼古丁输送系统（ENDS）的使用的方法。

    Compressed chewing gum tablet comprising taste-masking agent
    10.
    发明公开
    Compressed chewing gum tablet comprising taste-masking agent 审中-公开
    Komprimierte Kaugummitablette mit Geschmacksmaskierungsmittel

    公开(公告)号：EP2550967A1

    公开(公告)日：2013-01-30

    申请号：EP12189550.2

    申请日：2008-07-11

    申请人： Fertin Pharma A/S

    发明人： Andersen, Carsten ,  Lao, My Ly

    IPC分类号： A61K31/495 ,  A61K31/496 ,  A61K9/00 ,  A61K9/20 ,  A61P37/08

    CPC分类号： A61K31/495 ,  A61K9/0058 ,  A61K9/209 ,  A61K31/496

    摘要： The present invention relates to compressed chewing gum tablets comprising a useful antihistamine. In particular, the present invention is directed to compressed chewing gum tablet, which effectively mask the unpleasant tastes of compound according to formula (I), such as cetirizine, contained therein and methods for preparing such compressed chewing gum tablet.

    摘要翻译： 本发明涉及包含有用的抗组胺药的压缩口香糖片剂。 特别地，本发明涉及压缩口香糖片剂，其有效地掩盖了包含在其中的根据式（I）的化合物的令人不愉快的味道，以及制备这种压缩口香糖片剂的方法。