摘要:
A percutaneous oxygenator (10) has a Y-shaped tubular connector (12) and a number of hollow, gas-permeable fibers (14). One end of each fiber is located in the first upper arm (22) of the connector. The other end of each fiber is located in the other upper arm (24) of the connector, with each fiber forming a loop extending out of the lower opening of the connector. The device is inserted through a single small incision into the patient's venous system. An oxygen supply is attached to one of the upper arms of the connector. Oxygen flows through the hollow fibers and diffuses through the fiber wall into the blood. Carbon dioxide diffuses across the fiber wall from the blood into the interior of the fiber tubes. This carbon dioxide and any remaining oxygen exit the fibers and are vented to the atmosphere at the second upper arm of the connector.
摘要:
A percutaneous oxygenator is used to induce a retrograde perfusion of oxygenated blood in a vein to a compromised organ (e.g., to the brain following a stroke, or to the heart following a heart attack). The oxygenator (10) has an occluding balloon (25) and an oxygenation balloon (20) located upstream from the occluding balloon (25). A plurality of hollow gas-permeable fibers (14) surrounds the oxygenation balloon (20). The oxygenator (10) is inserted into a vein (84) downstream from the compromised organ. An external supply of air/oxygen is connected to create a flow through the fibers (14) and thereby oxygenate blood in the surrounding vein. A retrograde flow of oxygenated blood is induced in the vein to the compromised organ by first inflating the occluding balloon (25) to occlude the vein and then inflating the oxygenation balloon (20). Both balloons (25, 20) are then deflated to permit the normal antegrade flow of blood through the vein. This process of inflation and deflation is periodically repeated at a rate of about 30 to 60 cycles per minute. The percutaneous oxygenator (10) may be equipped with multiple occluding balloons for blocking several branches of the venous system leading from the compromised organ.
摘要:
An elongated intravenous percutaneous oxygenator is described having a first and a second set of hollow gas permeable and liquid impermeable fibers, the fibers of each set having an input end and an output end, at least three longitudinally spaced manifolds in communication with one of said input ends or output ends of said fibers, gas delivery means in communication with the input ends of said fibers and gas exhaust means in communication with said output ends and inflatable balloon means disposed longitudinally of said oxygenator so as to be surrounded by said fibers, and gas inflation means in communication with said balloon means for inflating and deflating the balloon means.
摘要:
An intravenous fiber membrane oxygenator is disclosed in several embodiments wherein the fibers either run at a transverse angle relative to the longitudinal axis of the oxygenator and/or are of a reduced length to optimize the gas transfer efficiency of the oxygenator. Various helical or spiral wraps of fibers are disclosed. One embodiment utilizes two sets of longitudinally extending fibers wherein the oxygen gas is moved in opposite directions from a central location of the oxygenator.
摘要:
A percutaneous oxygenator is used to induce a retrograde perfusion of oxygenated blood in a vein to a compromised organ (e.g., to the brain following a stroke, or to the heart following a heart attack). The oxygenator (10) has an occluding balloon (25) and an oxygenation balloon (20) located upstream from the occluding balloon (25). A plurality of hollow gas-permeable fibers (14) surrounds the oxygenation balloon (20). The oxygenator (10) is inserted into a vein (84) downstream from the compromised organ. An external supply of air/oxygen is connected to create a flow through the fibers (14) and thereby oxygenate blood in the surrounding vein. A retrograde flow of oxygenated blood is induced in the vein to the compromised organ by first inflating the occluding balloon (25) to occlude the vein and then inflating the oxygenation balloon (20). Both balloons (25, 20) are then deflated to permit the normal antegrade flow of blood through the vein. This process of inflation and deflation is periodically repeated at a rate of about 30 to 60 cycles per minute. The percutaneous oxygenator (10) may be equipped with multiple occluding balloons for blocking several branches of the venous system leading from the compromised organ.
摘要:
An intravenous fiber membrane oxygenator is disclosed in several embodiments wherein the fibers either run at a transverse angle relative to the longitudinal axis of the oxygenator and/or are of a reduced length to optimize the gas transfer efficiency of the oxygenator. Various helical or spiral wraps of fibers are disclosed. One embodiment utilizes two sets of longitudinally extending fibers wherein the oxygen gas is moved in opposite directions from a central location of the oxygenator.
摘要:
A percutaneous oxygenator (10) has a Y-shaped tubular connector (12) and a number of hollow, gas-permeable fibers (14). One end of each fiber is located in the first upper arm (22) of the connector. The other end of each fiber is located in the other upper arm (24) of the connector, with each fiber forming a loop extending out of the lower opening of the connector. The device is inserted through a single small incision into the patient's venous system. An oxygen supply is attached to one of the upper arms of the connector. Oxygen flows through the hollow fibers and diffuses through the fiber wall into the blood. Carbon dioxide diffuses across the fiber wall from the blood into the interior of the fiber tubes. This carbon dioxide and any remaining oxygen exit the fibers and are vented to the atmosphere at the second upper arm of the connector.