IMPROVED PERCUTANEOUS OXYGENATOR
    1.
    发明授权
    IMPROVED PERCUTANEOUS OXYGENATOR 失效
    改进经皮充氧。

    公开(公告)号:EP0470236B1

    公开(公告)日:1995-08-09

    申请号:EP91905350.4

    申请日:1991-02-14

    申请人: HATTLER, Brack G.

    IPC分类号: A61M1/18

    摘要: A percutaneous oxygenator (10) has a Y-shaped tubular connector (12) and a number of hollow, gas-permeable fibers (14). One end of each fiber is located in the first upper arm (22) of the connector. The other end of each fiber is located in the other upper arm (24) of the connector, with each fiber forming a loop extending out of the lower opening of the connector. The device is inserted through a single small incision into the patient's venous system. An oxygen supply is attached to one of the upper arms of the connector. Oxygen flows through the hollow fibers and diffuses through the fiber wall into the blood. Carbon dioxide diffuses across the fiber wall from the blood into the interior of the fiber tubes. This carbon dioxide and any remaining oxygen exit the fibers and are vented to the atmosphere at the second upper arm of the connector.

    PERCUTANEOUS OXYGENATOR FOR INDUCING A RETROGRADE PERFUSION OF OXYGENATED BLOOD
    2.
    发明公开
    PERCUTANEOUS OXYGENATOR FOR INDUCING A RETROGRADE PERFUSION OF OXYGENATED BLOOD 有权
    经皮氧合诱导血液OXYGEME​​RTEM逆行灌注

    公开(公告)号:EP1119390A4

    公开(公告)日:2002-03-06

    申请号:EP98940841

    申请日:1998-08-11

    申请人: HATTLER BRACK G

    发明人: HATTLER BRACK G

    IPC分类号: A61M1/16 A61M37/00

    摘要: A percutaneous oxygenator is used to induce a retrograde perfusion of oxygenated blood in a vein to a compromised organ (e.g., to the brain following a stroke, or to the heart following a heart attack). The oxygenator (10) has an occluding balloon (25) and an oxygenation balloon (20) located upstream from the occluding balloon (25). A plurality of hollow gas-permeable fibers (14) surrounds the oxygenation balloon (20). The oxygenator (10) is inserted into a vein (84) downstream from the compromised organ. An external supply of air/oxygen is connected to create a flow through the fibers (14) and thereby oxygenate blood in the surrounding vein. A retrograde flow of oxygenated blood is induced in the vein to the compromised organ by first inflating the occluding balloon (25) to occlude the vein and then inflating the oxygenation balloon (20). Both balloons (25, 20) are then deflated to permit the normal antegrade flow of blood through the vein. This process of inflation and deflation is periodically repeated at a rate of about 30 to 60 cycles per minute. The percutaneous oxygenator (10) may be equipped with multiple occluding balloons for blocking several branches of the venous system leading from the compromised organ.

    Inflatable percutaneous oxygenator with transverse hollow fibers
    3.
    发明公开
    Inflatable percutaneous oxygenator with transverse hollow fibers 失效
    带有横向中空纤维的充气式经皮氧合器

    公开(公告)号:EP0853951A3

    公开(公告)日:1998-07-29

    申请号:EP98200464.0

    申请日:1994-05-05

    IPC分类号: A61M1/16

    摘要: An elongated intravenous percutaneous oxygenator is described having a first and a second set of hollow gas permeable and liquid impermeable fibers, the fibers of each set having an input end and an output end, at least three longitudinally spaced manifolds in communication with one of said input ends or output ends of said fibers, gas delivery means in communication with the input ends of said fibers and gas exhaust means in communication with said output ends and inflatable balloon means disposed longitudinally of said oxygenator so as to be surrounded by said fibers, and gas inflation means in communication with said balloon means for inflating and deflating the balloon means.

    摘要翻译: 描述了一种细长的静脉内经皮氧合器,其具有第一组和第二组中空透气且不透液体的纤维,每组纤维具有输入端和输出端,至少三个纵向间隔开的歧管,与所述输入 与所述纤维的输入端连通的气体输送装置和与所述输出端连通的排气装置,以及沿所述充氧器的纵向设置的可膨胀气囊装置,以便被所​​述纤维包围,并且气体 与所述球囊装置连通的膨胀装置,用于使球囊装置膨胀和收缩。

    Inflatable percutaneous oxygenator with transverse hollow fibers
    5.
    发明公开
    Inflatable percutaneous oxygenator with transverse hollow fibers 失效
    Perkutaner,aufblasbarer氧化剂mit transversalen Hohlfasern。

    公开(公告)号:EP0631790A2

    公开(公告)日:1995-01-04

    申请号:EP94630030.8

    申请日:1994-05-05

    IPC分类号: A61M1/16

    摘要: An intravenous fiber membrane oxygenator is disclosed in several embodiments wherein the fibers either run at a transverse angle relative to the longitudinal axis of the oxygenator and/or are of a reduced length to optimize the gas transfer efficiency of the oxygenator. Various helical or spiral wraps of fibers are disclosed. One embodiment utilizes two sets of longitudinally extending fibers wherein the oxygen gas is moved in opposite directions from a central location of the oxygenator.

    摘要翻译: 在几个实施方案中公开了静脉内纤维膜氧合器,其中纤维相对于氧合器的纵向轴线以横向角度运行和/或具有减小的长度以优化氧合器的气体转移效率。 公开了各种螺旋或螺旋的纤维卷。 一个实施例使用两组纵向延伸纤维,其中氧气从氧合器的中心位置沿相反方向移动。

    PERCUTANEOUS OXYGENATOR FOR INDUCING A RETROGRADE PERFUSION OF OXYGENATED BLOOD
    6.
    发明公开
    PERCUTANEOUS OXYGENATOR FOR INDUCING A RETROGRADE PERFUSION OF OXYGENATED BLOOD 有权
    经皮氧合诱导血液OXYGEME​​RTEM逆行灌注

    公开(公告)号:EP1119390A1

    公开(公告)日:2001-08-01

    申请号:EP98940841.4

    申请日:1998-08-11

    申请人: HATTLER, Brack G.

    发明人: HATTLER, Brack G.

    IPC分类号: A61M37/00

    摘要: A percutaneous oxygenator is used to induce a retrograde perfusion of oxygenated blood in a vein to a compromised organ (e.g., to the brain following a stroke, or to the heart following a heart attack). The oxygenator (10) has an occluding balloon (25) and an oxygenation balloon (20) located upstream from the occluding balloon (25). A plurality of hollow gas-permeable fibers (14) surrounds the oxygenation balloon (20). The oxygenator (10) is inserted into a vein (84) downstream from the compromised organ. An external supply of air/oxygen is connected to create a flow through the fibers (14) and thereby oxygenate blood in the surrounding vein. A retrograde flow of oxygenated blood is induced in the vein to the compromised organ by first inflating the occluding balloon (25) to occlude the vein and then inflating the oxygenation balloon (20). Both balloons (25, 20) are then deflated to permit the normal antegrade flow of blood through the vein. This process of inflation and deflation is periodically repeated at a rate of about 30 to 60 cycles per minute. The percutaneous oxygenator (10) may be equipped with multiple occluding balloons for blocking several branches of the venous system leading from the compromised organ.

    IMPROVED PERCUTANEOUS OXYGENATOR
    9.
    发明公开
    IMPROVED PERCUTANEOUS OXYGENATOR 失效
    改进的经皮氧疗器

    公开(公告)号:EP0470236A4

    公开(公告)日:1992-07-22

    申请号:EP91905350

    申请日:1991-02-14

    申请人: HATTLER, BRACK G.

    摘要: A percutaneous oxygenator (10) has a Y-shaped tubular connector (12) and a number of hollow, gas-permeable fibers (14). One end of each fiber is located in the first upper arm (22) of the connector. The other end of each fiber is located in the other upper arm (24) of the connector, with each fiber forming a loop extending out of the lower opening of the connector. The device is inserted through a single small incision into the patient's venous system. An oxygen supply is attached to one of the upper arms of the connector. Oxygen flows through the hollow fibers and diffuses through the fiber wall into the blood. Carbon dioxide diffuses across the fiber wall from the blood into the interior of the fiber tubes. This carbon dioxide and any remaining oxygen exit the fibers and are vented to the atmosphere at the second upper arm of the connector.

    摘要翻译: 经皮充氧器(10)具有Y形管状连接器(12)和许多中空的透气纤维(14)。 每根光纤的一端位于连接器的第一上臂(22)内。 每根光纤的另一端位于连接器的另一个上臂(24)中,每根光纤形成一个从连接器的下部开口伸出的环。 该装置通过一个小切口插入患者的静脉系统。 氧气供应器连接到连接器的上臂之一。 氧气流过中空纤维并通过纤维壁扩散到血液中。 二氧化碳通过纤维壁从血液扩散到纤维管的内部。 该二氧化碳和任何剩余的氧气从纤维排出并排放到连接器第二上臂处的大气中。