公开(公告)号：EP4167876A1

公开(公告)日：2023-04-26

申请号：EP21825970.3

申请日：2021-06-18

申请人： Histosonics, Inc.

发明人： STOPEK, Joshua ,  CANNATA, Jonathon ,  GRUMBIR, Justin ,  CROWLEY, Thomas

IPC分类号： A61B17/225

公开(公告)号：EP2800530B1

公开(公告)日：2017-07-19

申请号：EP13733624.4

申请日：2013-01-07

申请人： Histosonics, Inc.

发明人： BERTOLINA, James, A. ,  RAKIC, Aleksandra

IPC分类号： A61N7/02 ,  A61N7/00 ,  A61B17/225 ,  A61B8/12

CPC分类号： A61N7/00 ,  A61B8/12 ,  A61B8/4444 ,  A61B2018/00547 ,  A61B2090/378 ,  A61N7/02 ,  A61N2007/006 ,  A61N2007/0065 ,  A61N2007/0078 ,  A61N2007/0091

公开(公告)号：EP2470087A4

公开(公告)日：2014-03-19

申请号：EP10814303

申请日：2010-08-26

申请人： UNIV MICHIGAN ,  HISTOSONICS INC

发明人： CAIN CHARLES A ,  HALL TIMOTHY L ,  ROBERTS WILLIAM W ,  XU ZHEN ,  FOWLKES J BRIAN ,  DAVISON THOMAS W

IPC分类号： A61B17/225 ,  A61B6/12 ,  A61B8/00 ,  A61B18/26

CPC分类号： A61N7/00 ,  A61B8/00 ,  A61B17/225 ,  A61B17/2256 ,  A61B2017/00172 ,  A61B2017/22008 ,  A61B2090/378

摘要： A medical imaging and therapy device is provided that may include any of a number of features. One feature of the device is that it can deliver Lithotripsy therapy to a patient, so as to fractionate urinary stones. Another feature of the device is that it can deliver Histotripsy therapy to a patient, so as to erode urinary stones. In some embodiments, the medical imaging and therapy device is configured to target and track urinary stones in the patient during therapy. Methods associated with use of the medical imaging and therapy device are also covered.

公开(公告)号：EP2467062A2

公开(公告)日：2012-06-27

申请号：EP10810498.5

申请日：2010-08-17

申请人： Histosonics, Inc. ,  The Regents Of The University Of Michigan

发明人： JAHNKE, Russell ,  BERTOLINA, James ,  ROBERTS, William ,  CAIN, Charles ,  TEOFILOVIC, Dejan ,  DAVISON, Thomas, W.

IPC分类号： A61B8/14 ,  A61N7/00

CPC分类号： A61N7/00 ,  A61B8/12 ,  A61B8/4272 ,  A61B8/4281 ,  A61B8/445 ,  A61B17/2251 ,  A61B17/2256 ,  A61B2017/00274 ,  A61B2017/2253 ,  A61B2018/00547 ,  A61B2090/378 ,  A61N2007/0039 ,  A61N2007/0043

摘要： A medical imaging and therapy device is provided that may include any of a number of features. One feature of the device is that it can acoustically couple an ultrasound therapy transducer to a patient. In some embodiments, the medical imaging and therapy device is configured to conform to the anatomy of a patient's perineal area to acoustically couple an ultrasound therapy transducer to the patient for treatment of BPH. The medical imaging and therapy device can be used in therapeutic applications such as Histotripsy, Lithotripsy, and HIFU, for example. Methods associated with use of the medical imaging and therapy device are also covered.

公开(公告)号：EP4166194A1

公开(公告)日：2023-04-19

申请号：EP22213038.7

申请日：2014-07-03

申请人： Histosonics, Inc. ,  The Regents of The University of Michigan

发明人： CANNATA, Jonathan ,  HALL, Timothy L. ,  MAXWELL, Adam ,  TEOFILOVIC, Dejan

IPC分类号： A61N7/00 ,  A61B8/00 ,  A61B17/22

摘要： Methods and devices for producing cavitation in tissue are provided. In one embodiment, a shock scattering method of Histotripsy therapy comprises delivering an initiation pressure waveform from an ultrasound therapy transducer into tissue, the initiation pressure waveform being configured to produce at least one bubble in the tissue, delivering a scattering pressure waveform from the ultrasound therapy transducer into the at least one bubble within a life-cycle of the at least one bubble, and producing cavitation nuclei near the at least one bubble with the scattering pressure waveform. The scattering pressure waveform can be delivered during the life-cycle of the at least one bubble. In some embodiments, the scattering pressure waveform is delivered within 5 µs to 1 s of the initiation pressure waveform. Systems for performing shock scattering Histotripsy therapy are also discussed.

公开(公告)号：EP3016594A4

公开(公告)日：2017-06-14

申请号：EP14819742

申请日：2014-07-03

申请人： HISTOSONICS INC ,  UNIV MICHIGAN REGENTS

发明人： CANNATA JONATHAN ,  HALL TIMOTHY L ,  MAXWELL ADAM ,  TEOFILOVIC DEJAN

IPC分类号： A61B8/00 ,  A61B17/22

CPC分类号： A61N7/00 ,  A61B17/22004 ,  A61B17/225 ,  A61B2017/00176 ,  A61B2017/22008 ,  A61B2017/22028 ,  A61N2007/0039 ,  A61N2007/0078

公开(公告)号：EP2467062B1

公开(公告)日：2017-01-18

申请号：EP10810498.5

申请日：2010-08-17

申请人： Histosonics, Inc. ,  The Regents of The University of Michigan

发明人： JAHNKE, Russell ,  BERTOLINA, James ,  ROBERTS, William ,  CAIN, Charles ,  TEOFILOVIC, Dejan ,  DAVISON, Thomas, W.

IPC分类号： A61B8/14 ,  A61N7/00

CPC分类号： A61N7/00 ,  A61B8/12 ,  A61B8/4272 ,  A61B8/4281 ,  A61B8/445 ,  A61B17/2251 ,  A61B17/2256 ,  A61B2017/00274 ,  A61B2017/2253 ,  A61B2018/00547 ,  A61B2090/378 ,  A61N2007/0039 ,  A61N2007/0043

公开(公告)号：EP4114520A1

公开(公告)日：2023-01-11

申请号：EP21765415.1

申请日：2021-03-08

申请人： Histosonics, Inc.

发明人： STOPEK, Joshua

IPC分类号： A61N7/02 ,  A61B17/22 ,  A61B17/225 ,  A61B34/30 ,  A61N7/00

公开(公告)号：EP3886737A1

公开(公告)日：2021-10-06

申请号：EP19891496.2

申请日：2019-11-27

申请人： Histosonics, Inc.

发明人： CANNATA, Jonathan, M. ,  MILLER, Ryan ,  DURYEA, Alexander, P. ,  TEOFILOVIC, Dejan ,  MLADENOVIC, Zeljko ,  RAKIC, Aleksandra ,  STOPEK, Joshua

IPC分类号： A61B17/22 ,  A61B8/00 ,  A61B17/225 ,  A61B90/00 ,  A61N7/00

公开(公告)号：EP2800530A4

公开(公告)日：2015-07-01

申请号：EP13733624

申请日：2013-01-07

申请人： HISTOSONICS INC

发明人： BERTOLINA JAMES A ,  RAKIC ALEKSANDRA

IPC分类号： A61N7/02 ,  A61B8/12 ,  A61B17/225 ,  A61N7/00

CPC分类号： A61N7/00 ,  A61B8/12 ,  A61B8/4444 ,  A61B2018/00547 ,  A61B2090/378 ,  A61N7/02 ,  A61N2007/006 ,  A61N2007/0065 ,  A61N2007/0078 ,  A61N2007/0091