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1.发明公开METHOD AND COMPOSITION FOR PREVENTING OR REDUCING THE SYMPTOMS OF INSULIN RESISTANCE SYNDROME 审中-公开方法和组合物用于预防或减少胰岛素抵抗综合征的症状
公开(公告)号：EP1438038A4
公开(公告)日：2005-09-21
申请号：EP02786372
申请日：2002-10-07
发明人： BAGCHI DEBASIS , PREUSS HARRY G , KOTHARI SHIL C
IPC分类号： C07D213/80 , A61K31/05 , A61K31/095 , A61K31/10 , A61K31/185 , A61K31/19 , A61K31/194 , A61K31/28 , A61K31/353 , A61K31/44 , A61K31/455 , A61K31/555 , A61K31/704 , A61K31/7048 , A61K33/04 , A61K33/24 , A61K33/30 , A61K33/32 , A61K45/06 , A61P3/04 , A61P3/06 , A61P3/10 , A61P5/50 , A61P9/10 , A61P9/12
CPC分类号： A61K31/185 , A61K31/05 , A61K31/095 , A61K31/19 , A61K31/194 , A61K31/28 , A61K31/44 , A61K31/455 , A61K31/704 , A61K31/7048 , A61K33/04 , A61K33/24 , A61K33/30 , A61K45/06 , Y10S514/824 , Y10S514/866 , Y10S514/909 , A61K2300/00
摘要： A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and administering to them an effective amount of a composition comprising niacin-bound chromium that prevents or reduces the symptoms. Compositions incorporating niacin-bound chromium and additional compounds also are disclosed that are particularly effective in synergistically preventing or reducing these symptoms.
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2.发明公开TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE 审中-公开DREIWERTIGE CHROMVERBINDUNGEN，ZUSAMMENSETZUNGEN UND VERFAHREN
公开(公告)号：EP2012770A2
公开(公告)日：2009-01-14
申请号：EP07760575.6
申请日：2007-04-12
IPC分类号： A61K31/198 , A61K33/24 , C07F11/00 , A61P7/00
CPC分类号： A61K31/4406 , A61K31/28 , A61K33/24 , A61K36/185 , A61K36/22 , A61K36/38 , A61K36/49 , A61K36/54 , A61K36/82 , C07C57/44 , C07C59/285 , C07C65/03 , C07C229/76 , A61K2300/00
摘要： The present invention provides chromium compounds which possess the ability to improve insulin sensitization, glucose tolerance, blood lipid metabolism, lean body mass, bioavailability, and safety as compared to chromium nicotinate, chromium picolinate and chromium histidine. These compounds are screened in terms of solubility, in vitro insulin sensitization, stability, and absorption as compared to chromium nicotinate, chromium picolinate and chromium histidine. The most promising chromium compounds are tested for their animal in vivo bioavailability, glucose metabolism, lipid metabolism and acute toxicity.
摘要翻译： 本发明提供具有改善胰岛素敏化，葡萄糖耐量，生物利用度，功效和安全性的能力的铬化合物，特别是二碳代二碳酸铬及其使用方法。
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3.发明公开COMPOSITION OF BERRY EXTRACTS THAT PREVENTS OR INHIBITS ANGIOGENESIS AND HELICOBACTER PYLORI 审中-公开哈·通的波啤酒含提取物抑制血管生成与BEHENDLUNG幽门螺杆菌感染的
公开(公告)号：EP1585533A2
公开(公告)日：2005-10-19
申请号：EP03754775.9
申请日：2003-09-18
发明人： BAGCHI, Debasis
摘要： A method and composition for preventing or inhibiting angiogenesis and Helicobacter pylori and providing a powerful antioxidant that provides numerous health benefits. The method involves administration of a composition incorporating specific edible berry extracts and the composition is comprised of specific edible berry extracts. The method and related composition effectively inhibit the release of growth factors that trigger angiogenesis, inhibit or prevent the growth of Helicobacter pylori and act as a powerful antioxidant with a high oxygen radical absorbance capacity (ORAL) and low cytotoxicity.
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4.发明公开METHOD FOR INCREASING SEROTONIN LEVELS IN A PERSON BY ADMINISTRATION OF A COMPOSITION INCORPORATING (-)-HYDROXYCITRIC ACID, AND RELATED COMPOSITIONS THEREOF 审中-公开法用于提高人的血清素水平通过给予组合物（ - ） - 羟基柠檬酸，以及相关组合物
公开(公告)号：EP1379261A2
公开(公告)日：2004-01-14
申请号：EP02733934.0
申请日：2002-04-01
IPC分类号： A61K35/78 , A61K31/555 , A61K31/19
CPC分类号： A61K31/19 , A23L33/105 , A23L33/165 , A23V2002/00 , A61K31/194 , A61K31/555 , A61K31/704 , A61K36/27 , A61K36/38 , A61K2300/00 , A23V2250/21 , A23V2250/1586
摘要： A method for increasing serotonin levels in a person includes identifying a person having a deficient serotonin level and administering to the person a composition incorporating hydroxycitric acid, preferably in the form of an extract of Garcinia cambogia, in an amount sufficient to increase the person's serotonin levels. The method also can incorporate administering chromium, preferably in the form of oxygen-coordinated, niacin-bound chromium, and gymnemic acid, preferably in the form of an extract of Gymnema sylvestre, to synergistically work to further increase serotonin levels in the person.
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5.发明公开COMPOSITIONS INCORPORATING (-)-HYDROXYCITRIC ACID, CHROMIUM, AND GYMNEMIC ACID, AND RELATED METHODS FOR PROMOTING HEALTHY BODY WEIGHT AND IMPROVING RELATED HEALTH FACTORS 审中-公开含化合物（ - ）羟基柠檬酸，Chrome和GYMNEMISCHE酸和方法，以保持健康的体重，提高健康水平影响因素
公开(公告)号：EP1461051A1
公开(公告)日：2004-09-29
申请号：EP02799288.2
申请日：2002-12-20
发明人： BAGCHI, Debasis , PREUSS, Harry, G.
IPC分类号： A61K33/24 , A61K35/78 , A61P3/04 , A61P3/06 , A61K31/194
CPC分类号： A61K31/19 , A23L33/105 , A23L33/165 , A23V2002/00 , A61K31/194 , A61K31/555 , A61K31/704 , A61K33/24 , A61K36/27 , A61K36/38 , A61K2300/00 , A23V2250/21 , A23V2250/1586
摘要： Methods for promoting healthy body weight and improving a variety of related physiological factors, including serum serotonin levels, serum leptin levels, fat oxidation, cholesterol levels, and body mass index, in persons or other mammals, include administering to those persons or other mammals effective amounts of hydroxycitric acid or a combination of hydroxycitric acid, chromium and gymnemic acid, which work synergistically to further to promote healthy body weight and improve these physiological factors.
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6.发明公开METHOD AND COMPOSITION FOR PREVENTING OR REDUCING THE SYMPTOMS OF INSULIN RESISTANCE SYNDROME 审中-公开方法和组合物用于预防或减少胰岛素抵抗综合征的症状
公开(公告)号：EP1438038A1
公开(公告)日：2004-07-21
申请号：EP02786372.9
申请日：2002-10-07
CPC分类号： A61K31/185 , A61K31/05 , A61K31/095 , A61K31/19 , A61K31/194 , A61K31/28 , A61K31/44 , A61K31/455 , A61K31/704 , A61K31/7048 , A61K33/04 , A61K33/24 , A61K33/30 , A61K45/06 , Y10S514/824 , Y10S514/866 , Y10S514/909 , A61K2300/00
摘要： A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and administering to them an effective amount of a composition comprising niacin-bound chromium that prevents or reduces the symptoms. Compositions incorporating niacin-bound chromium and additional compounds also are disclosed that are particularly effective in synergistically preventing or reducing these symptoms.
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7.发明公开METHOD FOR INCREASING SEROTONIN LEVELS IN A PERSON BY ADMINISTRATION OF A COMPOSITION INCORPORATING (-)-HYDROXYCITRIC ACID, AND RELATED COMPOSITIONS THEREOF 审中-公开VERFAHREN ZURERHÖHUNGDER SEROTONIN-SPIEGEL EINER PURD VERABREICHUNG EINER ZUSAMMENSETZUNG MIT（ - ） - HYDROXYCITRONENSÄURE，UND DAMIT VERWANDTE ZUSAMMENSETZUNGEN
公开(公告)号：EP1379261A4
公开(公告)日：2004-09-08
申请号：EP02733934
申请日：2002-04-01
发明人： OHIA SUNNY E , PREUSS HARRY G , BAGCHI DEBASIS
IPC分类号： A23L1/30 , A23L1/304 , A61K9/08 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/19 , A61K31/194 , A61K31/455 , A61K31/555 , A61K31/704 , A61K33/24 , A61K36/18 , A61K36/27 , A61K36/38 , A61P1/14 , A61P3/04 , A61P25/00 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61K35/78 , A61P25/06
CPC分类号： A61K31/19 , A23L33/105 , A23L33/165 , A23V2002/00 , A61K31/194 , A61K31/555 , A61K31/704 , A61K36/27 , A61K36/38 , A61K2300/00 , A23V2250/21 , A23V2250/1586
摘要： A method for increasing serotonin levels in a person includes identifying a person having a deficient serotonin level and administering to the person a composition incorporating hydroxycitric acid, preferably in the form of an extract of Garcinia cambogia, in an amount sufficient to increase the person's serotonin levels. The method also can incorporate administering chromium, preferably in the form of oxygen-coordinated, niacin-bound chromium, and gymnemic acid, preferably in the form of an extract of Gymnema sylvestre, to synergistically work to further increase serotonin levels in the person.
摘要翻译： 用于增加人体内5-羟色胺水平的方法包括鉴定具有不足5-羟色胺水平的人并且以足以增加人5-羟色胺水平的量向人施用引入羟基柠檬酸的组合物，优选以藤黄果提取物的形式 。 该方法还可以合并施用铬，优选以氧配位烟酸结合铬和匙羹藤酸的形式，优选以匙羹藤提取物的形式施用以协同作用以进一步增加人体内的血清素水平。
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