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1.
公开(公告)号:EP4362926A1
公开(公告)日:2024-05-08
申请号:EP22834039.4
申请日:2022-06-28
发明人: DE MARTIN, Sara , MATTAREI, Andrea , PASUT, Gianfranco , MANFREDI, Paolo L. , INTURRISI, Charles E.
IPC分类号: A61K31/137 , A61K47/50 , A61P25/04
CPC分类号: A61K31/137 , A61P25/04 , A61K9/2054 , A61K9/2059 , A61K9/2846 , A61K9/2077
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2.
公开(公告)号:EP4125990A1
公开(公告)日:2023-02-08
申请号:EP21775946.3
申请日:2021-03-24
申请人: University of Padova , Institute for Research in Biomedicine , Manfredi, Paolo L. , Inturrisi, Charles, E.
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3.
公开(公告)号:EP4085044A1
公开(公告)日:2022-11-09
申请号:EP20908770.9
申请日:2020-12-30
申请人: University of Padova , Institute for Research in Biomedicine , Manfredi, Paolo L. , Inturrisi, Charles, E.
发明人: DE MARTIN, Sara , MATTAREI, Andrea , SGRIGNANI, Jacopo , CAVALLI, Andrea , MANFREDI, Paolo, L. , INTURRISI, Charles, E.
IPC分类号: C07C221/00 , C07C213/00 , C07C225/16
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公开(公告)号:EP4319733A1
公开(公告)日:2024-02-14
申请号:EP22785500.4
申请日:2022-04-08
发明人: MATTAREI, Andrea , BANZATO, Marco , FURLAN, Alberto , ONGARO, Alberto , HEASLEY, Brian, H. , TUCKER, Zachary, D. , MANFREDI, Paolo, L. , INTURRISI, Charles, E.
IPC分类号: A61K31/137 , C07B53/00 , C07C45/44
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公开(公告)号:EP3576739A2
公开(公告)日:2019-12-11
申请号:EP18706021.5
申请日:2018-01-31
IPC分类号: A61K31/485 , A61P25/00
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公开(公告)号:EP2906209B1
公开(公告)日:2018-06-20
申请号:EP13773543.7
申请日:2013-09-25
IPC分类号: A61K31/137 , A61P25/00 , A61P25/24
CPC分类号: A61K31/137 , A61K9/0019 , A61K45/06 , A61K2300/00
摘要: The present invention relates to a method of treating psychiatric symptoms in a subject having a NMDA receptor and a NE receptor which includes administering d-methadone, d-methadol, d-alpha-acetylmethadol, l-alpha-acetylmethadol, d-alpha-normethadol, l-alpha-normethadol, pharmaceutically acceptable salts thereof, or mixtures thereof, to the subject under conditions effective for the substance to bind to the NMDA receptor and NE receptor of the subject.
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