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公开(公告)号:EP4488260A1
公开(公告)日:2025-01-08
申请号:EP23762973.8
申请日:2023-03-02
Inventor: XUE, Tao , CHEN, Yilang
IPC: C07C225/20 , C07C225/00 , A61K31/215 , C07C221/00 , C07C253/30 , A61K31/135 , A61K31/277 , A61P25/24 , A61P25/00 , C07D307/68
Abstract: The present invention relates to a new aminoketone compound, and a preparation method therefor and the use thereof. Specifically, the compound of the present invention has a structure as shown in formula (I), wherein the definition of each group and substituent are as described in the description. Also disclosed in the present invention are a preparation method for the compound and the use thereof against depression.
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2.
公开(公告)号:EP3653296B1
公开(公告)日:2023-12-13
申请号:EP18831926.3
申请日:2018-07-12
Inventor: HOSONO, Hideo , GONG, Yutong , WU, Jiazhen , KITANO, Masaaki , YOKOYAMA, Toshiharu , LU, Yangfan , YE, Tiannan
IPC: B01J23/89 , B01J23/83 , B01J23/63 , B01J23/10 , B01J37/00 , B01J37/02 , B01J37/04 , B01J37/08 , B01J37/34 , C01C1/04 , C07C209/36 , C01B3/00 , C07C213/02 , C07C221/00 , C07C227/04 , C07C231/12 , C07C253/30
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公开(公告)号:EP3956300A1
公开(公告)日:2022-02-23
申请号:EP20720013.0
申请日:2020-04-16
Applicant: Janssen Pharmaceutica NV
Inventor: CHEN, Yi Cheng
IPC: C07C263/04 , C07C265/10 , C07C213/02 , C07C217/52 , C07C221/00 , C07C225/20 , C07C269/02 , C07C271/34
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公开(公告)号:EP3275868B1
公开(公告)日:2021-09-29
申请号:EP16768789.6
申请日:2016-03-23
Inventor: ISHIBASHI, Yuichiro , OCHI, Yosuke , MIYAKE, Noriaki , YAMAZAKI, Yusuke , SHIMIZU, Shota
IPC: C07D231/14 , C07C221/00 , C07C225/14 , C07D231/12
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5.
公开(公告)号:EP3774720A1
公开(公告)日:2021-02-17
申请号:EP19785180.1
申请日:2019-04-02
Applicant: Archer Daniels Midland Company
Inventor: BRAZDIL, James , ROGNESS, Donald , MA, Chi Cheng
IPC: C07C221/00 , C07C225/06 , C07C45/66 , C07C49/24 , C07C49/12 , B01J23/30 , B01J23/46
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公开(公告)号:EP3357898B1
公开(公告)日:2020-11-25
申请号:EP16851631.8
申请日:2016-09-28
Applicant: FUJIFILM Wako Pure Chemical Corporation
Inventor: KEMMOKU, Akira , HAGA, Yayoi , KAWAMOTO, Fumio
IPC: C07B63/02 , C07B33/00 , C07B63/00 , C07C45/29 , C07C47/02 , C07C47/228 , C07C49/04 , C07C49/403 , C07C49/786 , C07C49/807 , C07C221/00 , C07C223/06 , C07C225/22 , C07D213/50 , C07D307/46 , C07H17/08 , C07J1/00 , C07C315/02 , C07C49/303 , C07C49/78
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公开(公告)号:EP3196189B1
公开(公告)日:2020-09-23
申请号:EP15837423.1
申请日:2015-08-25
Applicant: Nippon Soda Co., Ltd.
Inventor: KOBAYASHI, Shinichi
IPC: C07C221/00 , C07C223/06 , C07D317/16 , C07D317/28 , C07B51/00 , C07B61/00
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公开(公告)号:EP2607300B1
公开(公告)日:2020-05-13
申请号:EP11818187.4
申请日:2011-08-16
Applicant: Shiono Chemical Co., Ltd.
Inventor: SAJIKI, Hironao , MONGUCHI, Yasunari , SAWAMA, Yoshinari , KONDO, Shinichi
IPC: C01B3/04 , C07C5/08 , C07C5/09 , C07C5/10 , C07C9/15 , C07C15/00 , C07C29/00 , C07C33/20 , C07C33/22 , C07C41/18 , C07C43/205 , C07B35/02 , C07B59/00 , C07C209/36 , C07C213/02 , C07C221/00 , C07C45/61
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9.
公开(公告)号:EP3341354A1
公开(公告)日:2018-07-04
申请号:EP16760285.3
申请日:2016-08-24
Applicant: Cody Laboratories, Inc.
Inventor: MKRTCHYAN, Gnel , YAO, Qingwei
IPC: C07C221/00 , C07C225/16 , A61P25/04 , A61K31/135
CPC classification number: C07C221/00 , C07B2200/07 , C07C213/00 , C07C225/16 , C07C227/18 , C07C253/30 , C07C229/12 , C07C215/08 , C07C255/42
Abstract: Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.
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公开(公告)号:EP2314566B1
公开(公告)日:2018-01-24
申请号:EP10186984.0
申请日:2010-10-08
Inventor: Bernardin, Aude , Bonnaffe, David , Texier-Nogues, Isabelle
IPC: C07C221/00 , C07D311/88 , C07F7/08
CPC classification number: C07C221/00 , C07B2200/11 , C07C2601/18 , C07D311/82 , C07F7/1804 , C07C225/14
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