PROSTASIN PARTIAL PEPTIDE AND ANTI-PROSTASIN ANTIBODY
    1.
    发明公开
    PROSTASIN PARTIAL PEPTIDE AND ANTI-PROSTASIN ANTIBODY 审中-公开
    前列腺素部分肽和抗前列腺素抗体

    公开(公告)号:EP2020417A1

    公开(公告)日:2009-02-04

    申请号:EP07743225.0

    申请日:2007-05-01

    摘要: An object of the present invention is to provide an antibody that can be stably supplied and can react with prostasin under non-denaturation and denaturation conditions, and an antigen peptide for preparation of the antibody. The present invention relates to a peptide consisting of the amino acid sequence shown in SEQ ID NO: 1 or a peptide consisting of an amino acid sequence that has a deletion, a substitution, or an addition of one or several amino acids with respect to the amino acid sequence shown in SEQ ID NO: 1 and having antigenicity of prostasin. Furthermore, the present invention relates to an antibody prepared using the peptide as an antigen.

    摘要翻译: 本发明的目的在于提供一种抗体,其能够在非变性和变性条件下稳定地供应并且能够与前列腺素反应,并且提供用于制备该抗体的抗原肽。 本发明涉及由序列号1所示的氨基酸序列构成的肽或由相对于该氨基酸序列具有1个或数个氨基酸的缺失,取代或添加的氨基酸序列构成的肽 氨基酸序列如SEQ ID NO:1所示,具有prostasin的抗原性。 此外,本发明涉及使用该肽作为抗原制备的抗体。