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1.发明授权A NOVEL PROCESS FOR THE MANUFACTURE OF (+)-(S)-CLOPIDOGREL BISULFATE FORM-I 有权新方法的（+）的制备 - （S）-CLOPIDOGRELBISULFAT FORM我
公开(公告)号：EP1651646B1
公开(公告)日：2012-05-09
申请号：EP03817742.4
申请日：2003-08-04
申请人： Wockhardt Limited , Jaweed Mukarram, Siddiqui Mohammed , Merwade, Aravind Yekanathsa , Khan, Anjum Reyaz
发明人： JAWEED MUKARRAM, Siddiqui Mohammed, Wockhardt Ltd. , MERWADE, Aravind Yekanathsa, Wockhardt Ltd. , KHAN, Anjum Reyaz, Wockhardt Ltd.
IPC分类号： C07D495/04 , A61K31/4738 , A61P9/00
CPC分类号： C07D495/04
摘要： The present invention relates to a novel process for the manufacture of blood-platelet aggregation inhibiting agent. In particular, the present invention is directed to a process for the manufacture of Methyl-(+)-(S)-α-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-S-(4H)acetate bisulfate Form-I.
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公开(公告)号：EP1313749A2
公开(公告)日：2003-05-28
申请号：EP01958277.4
申请日：2001-08-23
申请人： Wockhardt Limited , Khan, Anjum Reyaz , Singh, Shiva Prasad , Jaweed Mukarram, Siddiqui Mohammed , Purohit, Manish
IPC分类号： C07H1/00
CPC分类号： C07D407/14
摘要： The present invention provides a stable form of azithromycin derivatives that act as antibiotics. These compounds are in anhydrous form and have increased stability over the hydrated forms.
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公开(公告)号：EP2155756B1
公开(公告)日：2015-08-05
申请号：EP08763137.0
申请日：2008-05-29
申请人： Wockhardt Limited , Shukla, Jagdish , Khan, Anjum Reyaz , Merwade, Arvind , Siddiqui, Mohammad Jaweed Mukarram , Kumar, Yatendra
发明人： SHUKLA, Jagdish , KHAN, Anjum Reyaz , MERWADE, Arvind , SIDDIQUI, Mohammad Jaweed Mukarram , KUMAR, Yatendra
IPC分类号： C07D495/04 , A61P7/00
CPC分类号： C07D495/04
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公开(公告)号：EP2155756A1
公开(公告)日：2010-02-24
申请号：EP08763137.0
申请日：2008-05-29
申请人： Wockhardt Research Centre , Shukla, Jagdish , Khan, Anjum Reyaz , Merwade, Arvind Yenkatesha , Siddiqui, Mohammad Jaweed Mukarram , Kumar, Yatendra
发明人： SHUKLA, Jagdish , KHAN, Anjum Reyaz , MERWADE, Arvind , SIDDIQUI, Mohammed Jaweed Mukarram , KUMAR, Yatendra
IPC分类号： C07D495/04 , A61P7/00
CPC分类号： C07D495/04
摘要： The invention relates to processes for the preparation of clopidogrel and salts thereof. The inventors have developed a process for preparing racemic clopidogrel by racemizing R(-) clopidogrel. The process includes the step of reacting R(-) clopidogrel with a powered anhydrous base in one or more solvents.
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5.发明公开A NOVEL PROCESS FOR THE MANUFACTURE OF (+)-(S)-CLOPIDOGREL BISULFATE FORM-I 有权制造（+） - （S） - 氯吡格雷二硫化物FORM-I的新方法
公开(公告)号：EP1651646A1
公开(公告)日：2006-05-03
申请号：EP03817742.4
申请日：2003-08-04
申请人： Wockhardt Limited , Jaweed Mukarram, Siddiqui Mohammed , Merwade, Aravind Yekanathsa , Khan, Anjum Reyaz
发明人： JAWEED MUKARRAM, Siddiqui Mohammed, Wockhardt Ltd. , MERWADE, Aravind Yekanathsa, Wockhardt Ltd. , KHAN, Anjum Reyaz, Wockhardt Ltd.
IPC分类号： C07D471/04
CPC分类号： C07D495/04
摘要： The present invention relates to a novel process for the manufacture of blood-platelet aggregation inhibiting agent. In particular, the present invention is directed to a process for the manufacture of Methyl-(+)-(S)-α-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-S-(4H)acetate bisulfate Form-I.
摘要翻译： 本发明涉及一种制备血小板聚集抑制剂的新方法。 具体地说，本发明涉及制备（+） - （S）-α-（2-氯苯基）-6,7-二氢噻吩并[3,2-c]吡啶-5-（ 4H）乙酸盐硫酸氢盐形式-I。
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6.发明公开A NOVEL PROCESS FOR THE MANUFACTURE OF (+)-(S)-CLOPIDOGREL BISULFATE FORM-I 有权NEUES VERFAHREN ZUR HERSTELLUNG VON（+） - （S）-CLOPIDOGRELBISULFAT FORM-I
公开(公告)号：EP1651646A4
公开(公告)日：2007-03-21
申请号：EP03817742
申请日：2003-08-04
IPC分类号： C07D495/04 , A61K31/4738 , A61P9/00
CPC分类号： C07D495/04
摘要： The present invention relates to a novel process for the manufacture of blood-platelet aggregation inhibiting agent. In particular, the present invention is directed to a process for the manufacture of Methyl-(+)-(S)-α-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-S-(4H)acetate bisulfate Form-I.
摘要翻译： 本发明涉及一种制备血小板聚集抑制剂的新方法。 具体地说，本发明涉及制备（+） - （S）-α-（2-氯苯基）-6,7-二氢噻吩并[3,2-c]吡啶-5-（ 4H）乙酸盐硫酸氢盐形式-I。
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公开(公告)号：EP1313749B1
公开(公告)日：2005-10-12
申请号：EP01958277.4
申请日：2001-08-23
申请人： Wockhardt Limited , Khan, Anjum Reyaz , Singh, Shiva Prasad , Jaweed Mukarram, Siddiqui Mohammed , Purohit, Manish
IPC分类号： C07H17/08 , A61K31/7048
CPC分类号： C07D407/14
摘要： The present invention provides a stable form of azithromycin derivatives that act as antibiotics. These compounds are in anhydrous form and have increased stability over the hydrated forms.
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公开(公告)号：EP1313749A4
公开(公告)日：2004-01-21
申请号：EP01958277
申请日：2001-08-23
申请人： WOCKHARDT LTD , KHAN ANJUM REYAZ , SINGH SHIVA PRASAD , JAWEED MUKARRAM SIDDIQUI MOHAM , PUROHIT MANISH
IPC分类号： C07H17/00 , A61K31/7052 , A61P31/04 , C07D407/14 , C07H17/08 , A61K31/7048
CPC分类号： C07D407/14
摘要： The present invention provides a stable form of azithromycin derivatives that act as antibiotics. These compounds are in anhydrous form and have increased stability over the hydrated forms.
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