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公开(公告)号：EP2190415A2
公开(公告)日：2010-06-02
申请号：EP08789518.1
申请日：2008-08-01
IPC分类号： A61K9/20
CPC分类号： A61K9/2013 , A61K9/2018 , A61K9/2027 , A61K9/2059 , A61K9/2077 , A61K9/2095 , A61K31/216
摘要： The invention relates to pharmaceutical compositions comprising non-micronized fenofibrate with one or more pharmaceutically acceptable vehicles. The invention also relates to pharmaceutical compositions comprising non-micronized fenofibrate with one or more cyclodextrin derivatives. The invention also relates to processes for the preparation of such compositions.
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公开(公告)号：EP2155756A1
公开(公告)日：2010-02-24
申请号：EP08763137.0
申请日：2008-05-29
申请人： Wockhardt Research Centre , Shukla, Jagdish , Khan, Anjum Reyaz , Merwade, Arvind Yenkatesha , Siddiqui, Mohammad Jaweed Mukarram , Kumar, Yatendra
发明人： SHUKLA, Jagdish , KHAN, Anjum Reyaz , MERWADE, Arvind , SIDDIQUI, Mohammed Jaweed Mukarram , KUMAR, Yatendra
IPC分类号： C07D495/04 , A61P7/00
CPC分类号： C07D495/04
摘要： The invention relates to processes for the preparation of clopidogrel and salts thereof. The inventors have developed a process for preparing racemic clopidogrel by racemizing R(-) clopidogrel. The process includes the step of reacting R(-) clopidogrel with a powered anhydrous base in one or more solvents.
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公开(公告)号：EP2148655A2
公开(公告)日：2010-02-03
申请号：EP08737878.2
申请日：2008-04-16
申请人： Wockhardt Research Centre , Ujjainkar, Amol , Balla Pattabhi, Srinivas , Khan, Abdul Rehman , Murali, Narayanan , Jain, Girish Kumar
发明人： UJJAINKAR, Amol , BALLA PATTABHI, Srinivas , KHAN, Abdul Rehman , MURALI, Narayanan , JAIN, Girish Kumar
CPC分类号： A61K31/4365 , A61K9/1652 , A61K9/2009 , A61K9/2013 , A61K9/2054 , A61K9/2077 , A61K9/284 , A61K9/2866
摘要： The invention relates to pharmaceutical compositions comprising clopidogrel or monobasic acid salts thereof in admixture with one or more hydrated excipients. The invention also relates to pharmaceutical compositions comprising clopidogrel or monobasic acid salts thereof which are free of any moisture scavenger. The invention also relates to processes for the preparation of such compositions.
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4.发明公开
公开(公告)号：EP2293791A1
公开(公告)日：2011-03-16
申请号：EP09708991.6
申请日：2009-02-06
IPC分类号： A61K31/275 , A61K9/14 , A61K47/26 , A61K9/16 , A61K9/26
CPC分类号： A61K9/145 , A61K9/1635 , A61K9/2018 , A61K9/2027 , A61K31/275
摘要： The present invention relates to pharmaceutical compositions comprising entacapone or pharmaceutically acceptable salts thereof along with one or more sugar alcohols; wherein the entacapone is co-micronized with one or more sugar alcohols. The invention also relates to processes of making such compositions.
摘要翻译： 本发明涉及包含恩他卡朋或其药学上可接受的盐以及一种或多种糖醇的药物组合物; 其中恩他卡朋与一种或多种糖醇共微粉化。 本发明还涉及制造这种组合物的方法。
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公开(公告)号：EP2268268A2
公开(公告)日：2011-01-05
申请号：EP08807816.7
申请日：2008-09-26
发明人： TALWAR, Munish , DABRE, Rahul , KAPOOR, Ritesh , VERMA, Himanshu , JAIN, Nitin , JAIN, Girish Kumar
CPC分类号： A61K9/0056 , A61K9/2054 , A61K9/7007 , A61K31/192 , A61K31/235
摘要： The invention relates to orally disintegrating pharmaceutical compositions comprising rhein or diacerein, or salts or esters or prodrugs thereof, and processes for preparing such compositions.
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6.发明公开PHARMACEUTICAL COMPOSITIONS OF ENTACAPONE, LEVODOPA AND CARBIDOPA WITH IMPROVED BIOAVAILABILITY 有权恩他卡朋，左旋多巴和卡比多巴与提高的生物利用率的药物组合物
公开(公告)号：EP2252284A1
公开(公告)日：2010-11-24
申请号：EP09709056.7
申请日：2009-02-06
IPC分类号： A61K31/275 , A61K9/14 , A61K47/26 , A61K9/16 , A61K9/26 , A61K31/195 , A61K31/198
CPC分类号： A61K9/14 , A61K9/145 , A61K9/1635 , A61K9/1652 , A61K9/2054 , A61K9/2077 , A61K31/195 , A61K31/198 , A61K31/275 , A61K31/277
摘要： The present invention relates to single oral dose pharmaceutical compositions comprising a combination of entacapone, levodopa and carbidopa, or salts thereof along with one or more sugar alcohols, wherein the entacapone is co-micronized with one or more sugar alcohols. The composition of the invention exhibits bioequivalence to commercially available entacapone, levodopa and carbidopa combination formulation marketed under the trade name Stalevo200®. The invention also relates to processes for making such compositions.
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公开(公告)号：EP2207532A2
公开(公告)日：2010-07-21
申请号：EP08807676.5
申请日：2008-09-16
IPC分类号： A61K9/14 , A61K9/58 , A61K31/192 , A61P19/02
CPC分类号： A61K9/146 , A61K9/145 , A61K9/1641 , A61K9/4808 , A61K9/5078 , A61K9/5084 , A61K31/192
摘要： The invention relates to pharmaceutical compositions of rhein or diacerein, or salts or esters or prodrugs thereof which are bioequivalent to a 50 mg diacerein formulation marketed under the trade name Art 50®. The compositions exhibit no variability in fed and fasted state conditions. The compositions also result in significant reduction in side effects such as, soft stools as compared to Art 50®. The invention also relates to the methods for preparing such compositions.
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公开(公告)号：EP2114374A2
公开(公告)日：2009-11-11
申请号：EP07866569.2
申请日：2007-12-20
申请人： Wockhardt Research Centre , Kalantri, Mahesh Rameshwar , Goswami, Sudhir , Murali, Narayanan , Jain, Girish Kumar
IPC分类号： A61K9/14
CPC分类号： A61K9/2095 , A61K9/2018 , A61K9/2054
摘要： The invention relates to pharmaceutical compositions comprising entacapone or pharmaceutically acceptable salts thereof. The invention also relates to processes for the preparation of such compositions.
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公开(公告)号：EP2056844A2
公开(公告)日：2009-05-13
申请号：EP07804796.6
申请日：2007-08-22
发明人： SINDKHEDKAR, Milind Dattatraya , DESAI, Vijaya, Narayan , LORIYA, Rajesh, Maganlal , PATEL, Mahesh, Vithalbhai , TRIVEDI, Bharat, Kalidas , BORA, Rajesh, Onkardas , DIWAKAR, Santosh, Devidas , JADHAV, Ganesh, Rajaram , PAWAR, Shivaji, Sampatrao
IPC分类号： A61K31/7048
CPC分类号： C07D493/04
摘要： The present invention provides compounds having antimicrobial activity for preventing and treating diseases caused by microbial infections. Thus, the present invention relates to novel • semi-synthetic 11,12-γ lactone macrolides and ketolides having antimicrobial activity, processes for making compounds as well as pharmaceutical compositions containing said compounds as active ingredients and methods of treating microbial infections with the compounds.
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公开(公告)号：EP2207531A1
公开(公告)日：2010-07-21
申请号：EP08807835.7
申请日：2008-09-27
IPC分类号： A61K9/107 , A61K9/48 , A61K47/44 , A61K31/222
CPC分类号： A61K31/235 , A61K9/1075 , A61K9/4825 , A61K9/4858 , A61K31/222 , A61K47/44
摘要： The invention relates to self emulsifying drug delivery system based compositions of rhein or diacerein, or salts or esters or prodrugs thereof which are bioequivalent to a 50 mg diacerein formulation marketed under the trade name Art 50 ®. The compositions exhibit no variability in fed and fasted state conditions. The compositions also result in significant reduction in side effects such as, soft stools effects as compared to Art 50 ®. The invention also relates to methods for preparing such compositions.
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