UTILISATION D'UN ISOTHIOCYANATE, D'UN THIOCYANATE OU DE LEUR MELANGE EN TANT QUE DEPIGMENTANT
    7.
    发明公开
    UTILISATION D'UN ISOTHIOCYANATE, D'UN THIOCYANATE OU DE LEUR MELANGE EN TANT QUE DEPIGMENTANT 审中-公开
    使用异硫氰酸酯,硫氰酸或其MIX AS HAUTDEPIGMENTIERUNGSMITTEL

    公开(公告)号:EP1353644A1

    公开(公告)日:2003-10-22

    申请号:EP02700395.3

    申请日:2002-01-24

    申请人: Lmd

    发明人: JEAN, Daniel

    IPC分类号: A61K7/48

    摘要: The invention concerns the use if isothiocyanate of general formula (I): R1-N=C=S wherein: R1 represents an alkyl, alkenyl, alkynyl, aryl, acetyl, alkylcarbonyl, alkoxy, cycloalkyl, aryloxy, arylcarbonyl group, carboxylic acid or a -(CH2)nR3 group wherein n represents an integer ranging between 1 and 5 and R3 represents a polar functional group, advantageously a halogen atom, a sulphoxide, carbonyl, nitro, thioester, thioether, sulphonyl, sulphinyl, nitrile group, carboxylic acid, carboxylic ester, alkylthio or hydroxyl, a thiocyanate of general formula (II): R2-S=C=N wherein: R2 represents an alkyl, alkenyl, alkynyl, aryl, acetyl, alkylcarbonyl, alkoxy, cycloalkyl, aryloxy, arylcarbonyl group, carboxylic acid, carboxylic ester or a -(CH2)nR3 group, wherein n represents an integer ranging between 1 and 5 and R3 represents a polar functional group, advantageously a halogen atom, a sulphoxide, carbonyl, nitro, thioester, thioether, sulphonyl, sulphinyl, nitrile group, carboxylic acid, carboxylic ester, alkylthio or hydroxyl, or mixtures thereof for making a medicine or a cosmetic composition for inhibiting tyrosinase.

    DERIVES PHENYLPROPANOIQUES ET COMPOSITIONS LES CONTENANT STIMULANT DE LA LIBIDO ET DE SES MECANISMES PHYSIOLOGIQUES ASSOCIES
    10.
    发明公开
    DERIVES PHENYLPROPANOIQUES ET COMPOSITIONS LES CONTENANT STIMULANT DE LA LIBIDO ET DE SES MECANISMES PHYSIOLOGIQUES ASSOCIES 审中-公开
    苯基衍生物和含有组合物来刺激性欲和相关生理机制

    公开(公告)号:EP1684740A1

    公开(公告)日:2006-08-02

    申请号:EP04805301.1

    申请日:2004-10-25

    申请人: Lmd

    CPC分类号: A61K31/235

    摘要: The invention relates to a compound having general formula (I), wherein: R2, R3, R4, R5 and R6, which may be identical or different, represent independently of each other a hydroxyl group, a hydrogen atom or radical -OR7 or -OCOR7, in which R7 represents an alkyl group at C1-C30, preferably at C1-C6; and R1 represents a radical having formula (II), wherein R8 represents a hydroxyl group or radical -OCOR9 in which R9 represents an alkyl group at C1-C6, preferably at C1-C3, or a radical group having formula (III), wherein R10 represents a group CH2OH, COOH, or a radical -CH2OR11 or -CH2OCOR11 in which R11 represents a linear or branched alkyl, alkenyl or alkynyl group at C1-C30, preferably at C1-C30, optionally substituted by a phenyl group, said phenyl group being optionally substituted by one or more groups that are selected from the group containing a hydroxyl group, radical -OR12 or radical -OCOR12, in which R12 represents an alkyl group at C1-C30, preferably at C1-C6. More specifically, the invention relates to the use of said compound for the production of a medicament that is intended to increase the amount of testosterone in the blood, to treat sexual dysfunctions in humans, to improve human sexual function, to treat sexual problems among men and women, to increase muscle mass, to treat impotence or to be used as an erectogenic agent. The invention further relates to a cosmetic composition, a food supplement containing a compound having general formula (I) and to the use thereof as an aphrodisiac.