公开(公告)号：EP1210146A4

公开(公告)日：2009-06-03

申请号：EP00944820

申请日：2000-06-23

申请人： LUMERX INC

发明人： GANZ ROBERT A

IPC分类号： A61L2/12 ,  A61B17/22 ,  A61B18/00 ,  A61B18/22 ,  A61B18/24 ,  A61M36/04 ,  A61N5/04 ,  A61N5/06 ,  A61N5/10 ,  H01J35/32 ,  A61N5/00

CPC分类号： A61N5/0601 ,  A61B18/24 ,  A61B2017/22051 ,  A61B2018/00982 ,  A61B2018/2261 ,  A61N5/1001 ,  A61N2005/0609 ,  A61N2005/0651 ,  A61N2005/0654 ,  A61N2005/0661 ,  H01J35/32 ,  H01J2235/164

公开(公告)号：EP1689492A1

公开(公告)日：2006-08-16

申请号：EP04810690.0

申请日：2004-11-10

申请人： Lumerx, Inc.

发明人： FRIEDMAN, Marc, D. ,  EVANS, Stephen ,  ZALESKY, Paul, J. ,  DAHM, Jon ,  LEVIN, Philip

IPC分类号： A61N5/06 ,  A61N5/067 ,  A61N5/00

CPC分类号： A61N5/0603 ,  A61B2090/036 ,  A61M25/1011 ,  A61N5/0601 ,  A61N5/062 ,  A61N2005/005 ,  A61N2005/0602 ,  A61N2005/0609 ,  A61N2005/0652 ,  A61N2005/0661 ,  A61N2005/0662 ,  F21S4/20 ,  F21Y2115/10 ,  H01L33/62 ,  H01L2224/32245 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/73265 ,  H01L2924/12044 ,  H01L2924/3025 ,  H01L2924/00014 ,  H01L2924/00

摘要： Physically flexible radiation-emitting probes and associated illumination methods and systems for delivering radiation or light to the interior of a lumen or cavity. Light-emitting devices are immersed in a flowing liquid coolant within a probe to provide high light output power, and convoluted electrical power buss structures provide physical flexibility of a probe about a longitudinal axis. The probes can be configured for delivering light to the interior of any lumen including for performing therapeutic medical procedures at locations in body lumens including the interior of the human gastrointestinal tract.

摘要翻译： 物理灵活的辐射发射探针和相关的照明方法和系统，用于将辐射或光传递到内腔或空腔的内部。 发光器件浸入到探针内的流动的液体冷却剂中以提供高的光输出功率，并且卷积的电力总线结构提供探针围绕纵向轴线的物理灵活性。 探针可以被配置为将光传送到任何腔的内部，包括用于在包括人胃肠道内部的体腔内的位置执行治疗性医学过程。

公开(公告)号：EP1494756A2

公开(公告)日：2005-01-12

申请号：EP03718049.4

申请日：2003-03-25

申请人： Lumerx, Inc.

发明人： TOLKOFF, Marc, Joshua ,  LEVINE, Andy, H.

IPC分类号： A61N5/01

CPC分类号： A61Q19/00 ,  A61K8/0212 ,  A61K2800/434 ,  A61N5/0616 ,  A61N2005/0647 ,  A61N2005/0656

摘要： The present invention provides the ability to treat acne with a device that can be worn by a patient for extended time periods. The device can, for example, enable the delivery of light for time periods that are longer than one might want to sit still in front of a stationary light source. The device is a flexible container that may be fitted to parts of the body to be treated. An example of such a flexible container is a mask for the face (1). The mask covers the face and has a strap (6) to hold it to the face. The mask is worn for a period of time needed to provide the desired amount of light energy to the issue.

公开(公告)号：EP1696996A1

公开(公告)日：2006-09-06

申请号：EP04810702.3

申请日：2004-11-10

申请人： Lumerx, Inc.

发明人： FRIEDMAN, Marc, D. ,  EVANS, Stephen ,  ZALESKY, Paul, J. ,  DAHM, Jon ,  LEVIN, Philip

IPC分类号： A61N1/06 ,  A61B18/18 ,  A61N5/06

CPC分类号： A61N5/0603 ,  A61B2090/036 ,  A61M25/1011 ,  A61N5/0601 ,  A61N5/062 ,  A61N2005/005 ,  A61N2005/0602 ,  A61N2005/0609 ,  A61N2005/0652 ,  A61N2005/0661 ,  A61N2005/0662 ,  F21S4/20 ,  F21Y2115/10 ,  H01L33/62 ,  H01L2224/32245 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/73265 ,  H01L2924/12044 ,  H01L2924/3025 ,  H01L2924/00014 ,  H01L2924/00

摘要： Physically flexible radiation-emitting probes and associated illumination methods and systems for delivering radiation or light to the interior of a lumen or cavity. Light-emitting devices are immersed in a flowing liquid coolant within a probe to provide high light output power, and convoluted electrical power buss structures provide physical flexibility of a probe about a longitudinal axis. The probes can be configured for delivering light to the interior of any lumen including for performing therapeutic medical procedures at locations in body lumens including the interior of the human gastrointestinal tract.

摘要翻译： 物理上灵活的辐射发射探针和相关的照明方法和系统，用于将辐射或光传递到腔或腔的内部。 发光器件浸入到探针内的流动的液体冷却剂中以提供高的光输出功率，并且卷积的电力总线结构提供探针围绕纵向轴线的物理灵活性。 探针可以被配置为将光传送到任何腔的内部，包括用于在包括人胃肠道内部的体腔内的位置执行治疗性医学过程。

公开(公告)号：EP1496994A2

公开(公告)日：2005-01-19

申请号：EP03746116.7

申请日：2003-04-02

申请人： Lumerx, Inc.

发明人： TOLKOFF, Marc, Joshua ,  ARCANGELI, Robert ,  LEVIN, Philip

IPC分类号： A61N5/067

CPC分类号： A61N5/0603 ,  A61B2018/2261 ,  A61N5/0624 ,  A61N2005/0609 ,  A61N2005/063 ,  A61N2005/0652 ,  A61N2005/0656 ,  A61N2005/0661 ,  A61N2005/0662 ,  A61N2005/0663

摘要： The present invention relates to the devices and methods for killing and/or debilitating pathogenic microorganisms, such as H. pylori bacteria within a patient's body. A light source (102) is provided that emits electromagnetic radiation having wavelengths within the visible spectrum. The light source can be internal and/or external to the patient's body. For embodiments having an external light source, a light guide (104) is provided for transferring the radiation from the light source to a location within the patient's body. The light guide has a proximal end optically coupled to the light source and a distal end dimensioned for insertion into a patient's body. A delivery element (106) is also provided to optically couple the radiation from the light to a location within a patient's body.

公开(公告)号：EP1496994A4

公开(公告)日：2008-04-16

申请号：EP03746116

申请日：2003-04-02

申请人： LUMERX INC

发明人： TOLKOFF MARC JOSHUA ,  ARCANGELI ROBERT ,  LEVIN PHILIP

IPC分类号： A61N5/06 ,  A61B18/22 ,  A61N20060101 ,  A61N2/00 ,  A61N5/067

CPC分类号： A61N5/0603 ,  A61B2018/2261 ,  A61N5/0624 ,  A61N2005/0609 ,  A61N2005/063 ,  A61N2005/0652 ,  A61N2005/0656 ,  A61N2005/0661 ,  A61N2005/0662 ,  A61N2005/0663

摘要： The present invention relates to the devices and methods for killing and/or debilitating pathogenic microorganisms, such as H. pylori bacteria within a patient's body. A light source (102) is provided that emits electromagnetic radiation having wavelengths within the visible spectrum. The light source can be internal and/or external to the patient's body. For embodiments having an external light source, a light guide (104) is provided for transferring the radiation from the light source to a location within the patient's body. The light guide has a proximal end optically coupled to the light source and a distal end dimensioned for insertion into a patient's body. A delivery element (106) is also provided to optically couple the radiation from the light to a location within a patient's body.

公开(公告)号：EP1696992A1

公开(公告)日：2006-09-06

申请号：EP04810864.1

申请日：2004-11-12

申请人： Lumerx, Inc.

发明人： ZALESKY, Paul, J. ,  FRIEDMAN, Marc, D. ,  EVANS, Stephen

IPC分类号： A61M29/00 ,  A61N5/10 ,  A61B18/24

CPC分类号： A61N5/0603 ,  A61B2090/036 ,  A61M25/1011 ,  A61N5/0601 ,  A61N5/062 ,  A61N2005/005 ,  A61N2005/0602 ,  A61N2005/0609 ,  A61N2005/0652 ,  A61N2005/0661 ,  A61N2005/0662 ,  F21S4/20 ,  F21Y2115/10 ,  H01L33/62 ,  H01L2224/32245 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/73265 ,  H01L2924/12044 ,  H01L2924/3025 ,  H01L2924/00014 ,  H01L2924/00

摘要： Catheters for performing therapeutic and diagnostic procedures within a body, including human or animal body cavities or lumens, and methods for use. One or more distancing member of the catheter can be used to position a sensor or a therapeutic device a minimum distance from a wall of a lumen or cavity. The catheter can include means for actively or passively controlling or modulating its position within the lumen or cavity during a procedure. Methods for using the catheter include nonocclusive deployment in the human gastrointestinal tract for phototherapy procedures, delivering electromagnetic radiation substantially homogeneously or in a desired pattern to the interior of a lumen.

摘要翻译： 用于在身体内执行治疗和诊断程序的导管，包括人体或动物体腔或腔，以及使用方法。 导管的一个或多个间距构件可用于将传感器或治疗装置定位在离腔或腔的壁最小距离处。 导管可以包括用于在手术过程中主动或被动地控制或调节其在腔或腔内的位置的装置。 使用导管的方法包括用于光疗过程的人胃肠道中的非闭塞性部署，将电磁辐射基本均匀地或以期望的图案递送至管腔的内部。

公开(公告)号：EP1496992A1

公开(公告)日：2005-01-19

申请号：EP03719752.2

申请日：2003-04-16

申请人： Lumerx, Inc.

发明人： TOLKOFF, Marc, Joshua ,  LEVIN, Philip ,  ARCANGELI, Robert ,  LEVINE, Andy ,  CHASTEEN, Thomas, G.

IPC分类号： A61N5/06 ,  F21K2/06

CPC分类号： A61N5/0624 ,  A61N5/06 ,  A61N5/0603 ,  A61N2005/0609 ,  A61N2005/0656 ,  A61N2005/0663 ,  F21K2/06

摘要： The present invention relates to a devices and methods for killing and/or debilitating pathogenic microorganisms in or on a patient’s body, such as light-sensitive bacteria including helicobacter pylori and/or propionibacterium acnes. A chemiluminescent light source provides electromagnetic radiation having predetermined wavelengths in the visible spectrum. The light wavelengths are selected for absorption by naturally-occurring photosensitive chemicals produced by the patient’s body.