公开(公告)号：EP1279679B1

公开(公告)日：2015-07-08

申请号：EP01971447.6

申请日：2001-04-11

申请人： Laboratorios Leti S.L. Sociedad Unipersonal

发明人： SOTO ALVAREZ, Manuel ,  ALONSO BEDATE, Carlos ,  REQUENA ROLANIA, José Maria

IPC分类号： C07K14/44 ,  G01N33/68 ,  A61K39/008

CPC分类号： C07K14/44 ,  A61K39/00 ,  Y02A50/41

摘要： A composition and method for stimulating an immune response against an antigen in immunised individuals or in cell groups. The composition comprises a protein called Lip2a Leishmania formed by a sequence of amino acids coded for by a sequence of DNA that comprises the nucleotides: 1-1 of nos. 778 to 1231 of SEQ. ID NO ! 1-2 or formed by a sequence of nucleotides able to hybridise with the sequence described in 1-1 under moderately strict hybridisation conditions and which would therefore code for a protein similar to Lip2a. The method comprises incubating said cells with said Lip2a protein in the presence or not of an antigen specific to a disease or infection.