公开(公告)号：EP4396358A1

公开(公告)日：2024-07-10

申请号：EP22865764.9

申请日：2022-08-31

Applicant: New York University

Inventor： ZHANG, Weimin ,  BOEKE, Jef

IPC: C12N15/85 ,  A61K48/00 ,  A61P11/00 ,  A61P9/00

CPC classification number: A61P9/00 ,  A61P11/00 ,  C12N15/63 ,  C12N15/907 ,  C12N9/22 ,  A01K67/0275 ,  A01K2217/07220130101 ,  A01K67/0278 ,  A01K2227/10520130101 ,  A01K2267/033720130101 ,  C12N2310/2020170501 ,  C12N15/102 ,  C12Y207/07 ,  C12N9/485 ,  C12Y304/17023 ,  C07K14/705 ,  A61K38/00

公开(公告)号：EP4356964A3

公开(公告)日：2024-06-19

申请号：EP23212830.6

申请日：2019-08-12

Applicant: New York University

Inventor： ALBERINI, Cristina, Maria ,  TRAUNER, Dirk ,  ARP, Christopher, James

IPC: A61K31/7012 ,  A61K31/7024 ,  A61K31/70 ,  A61K38/30 ,  C07K14/65 ,  A61P25/00

CPC classification number: C07K14/65 ,  A61P25/00 ,  A61K31/7024 ,  A61K31/70 ,  A61K31/7012 ,  A61K38/30

Abstract: Provided are methods for treatment of neurodevelopmental disorders, such as Angelman Syndrome and autism comprising administering to an individual a composition comprising an agonist ligand of IGF-2 receptor. The agonist ligand of IGF-2 receptor may be IGF-2, or mannose-6-phosphate or a derivative thereof. Compositions comprising mannose-6-phosphate derivatives are also disclosed.

公开(公告)号：EP4218794A3

公开(公告)日：2023-09-13

申请号：EP23159184.3

申请日：2010-06-10

Applicant: New York University

Inventor： SIGURDSSON, Einar M

IPC: A61K38/17 ,  C07K14/47 ,  A61K39/395 ,  A61P25/28 ,  G01N33/53

Abstract: The present invention relates to methods and compositions for treating, preventing, and diagnosing Alzheimer's Disease or other tauopathies in a subject by administering an immunogenic tau peptide or an antibody recognizing the immunogenic tau epitope under conditions effective to treat, prevent, or diagnose Alzheimer's Disease or other tauopathies. Also disclosed are methods of promoting clearance of aggregates from the brain of the subject and of slowing progression of tau-pathology related behavioral phenotype in a subject.

公开(公告)号：EP4218794A2

公开(公告)日：2023-08-02

申请号：EP23159184.3

申请日：2010-06-10

Applicant: New York University

Inventor： SIGURDSSON, Einar M

IPC: A61K38/17 ,  C07K14/47 ,  A61K39/395 ,  A61P25/28 ,  G01N33/53

Abstract: The present invention relates to methods and compositions for treating, preventing, and diagnosing Alzheimer's Disease or other tauopathies in a subject by administering an immunogenic tau peptide or an antibody recognizing the immunogenic tau epitope under conditions effective to treat, prevent, or diagnose Alzheimer's Disease or other tauopathies. Also disclosed are methods of promoting clearance of aggregates from the brain of the subject and of slowing progression of tau-pathology related behavioral phenotype in a subject.

公开(公告)号：EP4081527A1

公开(公告)日：2022-11-02

申请号：EP20908219.7

申请日：2020-12-16

Applicant: Dana-Farber Cancer Institute, Inc. ,  New York University

Inventor： GRAY, Nathanael, S. ,  WONG, Kwok-kin ,  ZHANG, Hua ,  ROSS, Camilla, Laulund Christensen

IPC: C07D487/04 ,  A61P35/00 ,  A61K31/4162 ,  C07D487/10 ,  A61K31/454 ,  A61K45/06

公开(公告)号：EP4040388A1

公开(公告)日：2022-08-10

申请号：EP22154873.8

申请日：2022-02-03

Applicant: Siemens Healthcare GmbH ,  New York University

Inventor： GEIGER, Bernhard ,  SCHWIER, Michael ,  GRBIC, Sasa ,  RAITHEL, Esther ,  LIN, Dana ,  CHABIN, Guillaume

IPC: G06T7/33 ,  G06T7/00 ,  G16H30/40

Abstract: Systems and methods for an intuitive display of one or more anatomical objects are provided. One or more 3D medical images of one or more anatomical objects of a patient are received. Correspondences between the one or more 3D medical images and points on a 2D map representing the one or more anatomical objects are determined. The 2D map is updated with patient information extracted from the one or more 3D medical images. The updated 2D map with the determined correspondences is output.

公开(公告)号：EP4007819A1

公开(公告)日：2022-06-08

申请号：EP20850355.7

申请日：2020-07-31

Applicant: New York University

Inventor： ABRAMSON, Steven ,  ATTUR, Mukundan

IPC: C12Q1/6883 ,  A61K48/00 ,  A61P19/02

公开(公告)号：EP3925619A1

公开(公告)日：2021-12-22

申请号：EP21174489.1

申请日：2014-09-05

Applicant: New York University

Inventor： YAMANASHI, Yoshihide ,  GRANOT, Tomer ,  MERUELO, Daniel

IPC: A61K39/00 ,  A61K39/12 ,  G01N33/574

Abstract: A method for treating a mammal harboring a tumor comprising the steps of identifying a tumor associated antigen (TAA) expressed by the tumor,, and parenterally administering to the mammal a therapeutically effective amount of a Sindbis viral vector carrying a gene encoding the TAA to the mammal sufficient to elicit an immune response directed against the tumor, and thereby treating, the tumor.

公开(公告)号：EP3883932A1

公开(公告)日：2021-09-29

申请号：EP19821358.9

申请日：2019-11-19

Applicant: New York University

Inventor： GREENLEE, William, J. ,  VAN DRIE, John ,  HUANG, Xinyan ,  SALZER, James ,  SHOHDY, Nadim

IPC: C07D471/04 ,  C07D471/18 ,  C07D487/04 ,  C07D519/00 ,  A61P25/00 ,  A61P35/00 ,  A61K31/407

公开(公告)号：EP3803431A1

公开(公告)日：2021-04-14

申请号：EP19812249.1

申请日：2019-06-03

Applicant: New York University

Inventor： NOVIKOV, Dmitry ,  FIEREMANS, Els ,  LEMBERSKIY, Gregory

IPC: G01R33/565