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    COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PERIPHERAL NERVE DISORDER
    4.
    发明公开
    COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PERIPHERAL NERVE DISORDER 审中-公开

    公开(公告)号：EP3466421A1

    公开(公告)日：2019-04-10

    申请号：EP17802758.7

    申请日：2017-05-22

    申请人： Osaka City University ,  Senju Pharmaceutical Co., Ltd.

    发明人： HIROTSUNE, Shinji

    IPC分类号： A61K31/27 ,  A61K31/341 ,  A61K31/351 ,  A61K31/44 ,  A61K31/4402 ,  A61P25/02 ,  A61P29/00 ,  A61P43/00

    摘要： The present invention provides a means for treating and/or preventing peripheral nerve disorder by facilitating regeneration of peripheral nerves. Specifically, the present invention provides a composition for treating and/or preventing peripheral nerve disorder comprising a compound represented by the general formula (I) :

    wherein R 1 is lower alkyl substituted with lower alkoxy, lower alkyl substituted with a heterocyclic group, a heterocyclic group, or a group represented by the formula (IIa):

    wherein R 4 is lower alkyl, R 5 is lower alkylene, and m is an integer of 1 to 6;
    R 2 is lower alkyl optionally substituted with phenyl; and
    R 3 is lower alkyl optionally substituted with halogen, lower alkoxy, or phenyl; condensed polycyclic hydrocarbon; or hydrogen.

    ELECTRIC CURRENT MEASUREMENT APPARATUS
    5.
    发明公开
    ELECTRIC CURRENT MEASUREMENT APPARATUS 审中-公开

    公开(公告)号：EP3244217A3

    公开(公告)日：2018-01-17

    申请号：EP17172922.1

    申请日：2014-09-10

    申请人： Osaka City University

    发明人： TSUJIMOTO, Hiroaki

    IPC分类号： G01R15/20 ,  G01R19/00 ,  G01R21/08

    CPC分类号： G01R15/205 ,  G01R15/207 ,  G01R19/0092 ,  G01R21/08

    摘要： Disclosed is an electric current measurement apparatus to measure a current flowing in a wire. The electric current measurement apparatus comprises a first magnetic element; a second magnetic element; a first current source capable of supplying a first alternating current to the first magnetic element; a second current source capable of supplying a second alternating current to the second magnetic element, a phase of the second alternating current being deviated from a phase of the first alternating current; a first lowpass filter configured to pass a low frequency component of an output from the first magnetic element; and a second low pass filter configured to pass a low frequency component of an output from the second magnetic element. The electric current measurement apparatus also comprises an operator configured to calculate a square root of a sum of squares of an output from the first low pass filter and an output from the second low pass filter, and / or an arc tangent value of the output from the first low pass filter and the output from the second low pass filter.

    CLAMP-TYPE AMMETER
    6.
    发明公开
    CLAMP-TYPE AMMETER 审中-公开

    公开(公告)号：EP3121606A4

    公开(公告)日：2017-12-13

    申请号：EP15764631

    申请日：2015-03-20

    申请人： UNIV OSAKA CITY

    发明人： TSUJIMOTO HIROAKI

    IPC分类号： G01R15/20 ,  G01R1/22 ,  G01R15/18

    CPC分类号： G01R1/22 ,  G01R15/186 ,  G01R15/202 ,  G01R15/207

    摘要： This clamp-type ammeter has a flexible substrate of which an inner wall is configured to be able to deform into a substantially cylindrical shape. The clamp-type ammeter has a plurality of magnetic sensor elements disposed at the inner wall of the flexible substrate. The clamp-type ammeter has a tube of which one end is connected to the flexible substrate. The clamp-type ammeter has an operation unit that is connected to the other end of the tube and that can operate the deformation of the flexible substrate.

    ELECTRIC CURRENT MEASUREMENT APPARATUS
    7.
    发明公开
    ELECTRIC CURRENT MEASUREMENT APPARATUS 审中-公开
    电流测量装置

    公开(公告)号：EP3244218A2

    公开(公告)日：2017-11-15

    申请号：EP17172923.9

    申请日：2014-09-10

    申请人： Osaka City University

    发明人： TSUJIMOTO, Hiroaki

    IPC分类号： G01R15/20 ,  G01R19/00 ,  G01R21/08

    CPC分类号： G01R15/205 ,  G01R15/207 ,  G01R19/0092 ,  G01R21/08

    摘要： Disclosed is an electric current measurement apparatus to measure a current flowing in a wire. The electric current measurement apparatus comprises a magnetic element; a current source capable of supplying an alternating current by changing a frequency thereof to the magnetic element; and a low pass filter configured to pass a low frequency component of an output from the magnetic element to output a voltage proportional to the current flowing in the wire.

    摘要翻译： 公开了一种用于测量在导线中流动的电流的电流测量设备。 电流测量装置包括磁性元件; 能够通过改变其频率到磁性元件来提供交流电流的电流源; 以及低通滤波器，被配置为传递来自所述磁性元件的输出的低频分量以输出与在所述导线中流动的电流成比例的电压。

    CLAMPING PROBE
    8.
    发明公开
    CLAMPING PROBE 审中-公开
    夹紧探针

    公开(公告)号：EP3216866A1

    公开(公告)日：2017-09-13

    申请号：EP15857156.2

    申请日：2015-11-06

    申请人： Osaka City University

    发明人： TACHIBANA Akira ,  TANABE Toshizumi

    IPC分类号： C12N15/09 ,  C12Q1/68 ,  G01N33/574

    CPC分类号： C12Q1/6827 ,  C12N15/09 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/6809 ,  C12Q1/6811 ,  C12Q1/6851 ,  C12Q1/6883 ,  G01N33/574

    摘要： A method in which a mutant gene present in a gene pool mixedly with a large number of wild-type genes can be simply, inexpensively and sensitively detected is developed and provided. A clamping probe that is connected to a target nucleic acid molecule in two regions of first and second target nucleic acid complementary regions so that a wild-type target nucleic acid molecule and a mutant-type target nucleic acid molecule can be distinguished from each other depending on a difference in complementarity to these target nucleic acid molecules is provided.

    摘要翻译： 开发并提供了一种方法，其中存在于基因库中的突变基因与大量野生型基因混合可以被简单，廉价且灵敏地检测。 在第一和第二靶核酸互补区的两个区域中与目标核酸分子连接的钳位探针，从而可以区分野生型靶核酸分子和突变型靶核酸分子， 提供了与这些靶核酸分子的互补性差异。