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1.发明公开FRACTURE-RESISTANT HELICAL STENT INCORPORATING BISTABLE CELLS AND METHODS OF USE 有权破坏与双稳态单元SAFE螺旋支架术
公开(公告)号：EP1998714A2
公开(公告)日：2008-12-10
申请号：EP07753961.7
申请日：2007-03-23
IPC分类号： A61F2/06
摘要： Vascular prostheses and methods of use are provided, wherein the vascular prosthesis includes a plurality of bistable unit cells configured to form a helical structure. A visualization catheter also is provided for use ensuring accurate measurement of a lesion and ensuring delivery and placement of the vascular prosthesis.
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公开(公告)号：EP1885285A2
公开(公告)日：2008-02-13
申请号：EP06770151.6
申请日：2006-05-09
发明人： BATES, Mark, C.
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： The present invention provides and apparatus and methods for emboli removal and stenting within the renal arteries having a catheter system having a distal occlusion element, a stent deployment section, and an emboli removal lumen. The occlusion element is disposed at a predetermined distance from the stent deployment section specific for use in the renal artery, and is constructed to reduce the potential for perforation or jailing during stent deployment. The apparatus further includes an array of radio-opaque markers disposed on the stent delivery catheter to facilitate accurate stent deployment within a renal artery.
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公开(公告)号：EP0961597B8
公开(公告)日：2005-12-28
申请号：EP98903673.6
申请日：1998-01-23
IPC分类号： A61F2/06
CPC分类号： A61F2/042 , A61B17/11 , A61B2017/1107 , A61F2/0004 , A61F2/0009 , A61F2/0022 , A61F2/02 , A61F2/064 , A61F2/91 , A61F2/915 , A61F2002/047 , A61F2002/91541 , A61F2002/9155 , A61F2002/91558 , A61F2002/91575 , A61F2230/0054 , A61F2250/0039 , F16K31/003
摘要： The present invention is directed to bistable cells and their use in devices, particularly medical devices such as stents (50), clamps and valves. An expandable stent formed of a plurality of bistable cells (52,54) is described. The stent has two or more stable configurations, including a first stable configuration with a first diameter and a second stable configuration with a second, larger diameter.
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公开(公告)号：EP1948289A2
公开(公告)日：2008-07-30
申请号：EP06836811.7
申请日：2006-11-01
发明人： BATES, Mark, C.
CPC分类号： A61M25/1029 , A61L29/126 , A61L29/18 , A61L2400/12 , A61M25/0045 , A61M25/0158 , A61M25/10 , A61M25/1036 , A61M2025/0042 , A61M2025/1079 , A61M2025/1084
摘要： Microcatheters catheters are provided having balloons incorporating radiopaque nanoparticles. Optionally, carbon nanotubes dispersed within the shaft may be configured to react to electrical stimulation, thereby providing a steerable distal end region on the microcatheter. Methods of making the foregoing microcatheters also are provided.
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公开(公告)号：EP1656892A2
公开(公告)日：2006-05-17
申请号：EP05022622.4
申请日：1998-01-23
CPC分类号： A61F2/042 , A61B17/11 , A61B2017/1107 , A61F2/0004 , A61F2/0009 , A61F2/0022 , A61F2/02 , A61F2/064 , A61F2/91 , A61F2/915 , A61F2002/047 , A61F2002/91541 , A61F2002/9155 , A61F2002/91558 , A61F2002/91575 , A61F2230/0054 , A61F2250/0039 , F16K31/003
摘要： The present invention is directed to bistable cells and their use in devices, particularly medical devices such as stents, clamps and valves. An expandable stent formed of a plurality of bistable cells is described. The stent has two or more stable configurations, including a first stable configuration with a first diameter and a second stable configuration with a second, larger diameter. A valve comprising a bistable cell for use in eliminating incontinence is also disclosed.
摘要翻译： 本发明涉及双稳态细胞及其在装置中的应用，特别是医疗装置，例如支架，夹具和瓣膜。 描述了由多个双稳态电池形成的可扩张支架。 支架具有两种或更多种稳定构型，包括具有第一直径的第一稳定构型和具有第二较大直径的第二稳定构型。 还公开了包括用于消除失禁的双稳态细胞的阀。
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公开(公告)号：EP1773441A2
公开(公告)日：2007-04-18
申请号：EP05773060.8
申请日：2005-07-18
发明人： BATES, Mark, C.
IPC分类号： A61M31/00
CPC分类号： A61B17/3478 , A61B2017/00247 , A61B2017/00398 , A61B2017/00871 , A61B2017/3411 , A61B2017/3484 , A61B2018/00392 , A61M5/3287
摘要： Methods and apparatus are provided for delivering a bioactive agent in a needle track formed in a target tissue mass, following formation of the needle track, by avoiding impingement of the agent against target tissue at high velocity or by using capillary action to draw the bioactive agent out of the needle during needle withdrawal. The apparatus comprises a catheter (31) and a needle (37) disposed within the catheter (31) and configured to be selectively extended into the tissue mass to a predetermined depth, while dispensing the agent simultaneously with retraction of the needle along the needle track. Alternatively, or in addition, the needle (37) may be configured to create a tissue space surrounding a distal or lateral surface of the needle (37), into which the bioactive agent to be infused.
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7.发明公开
公开(公告)号：EP1773440A2
公开(公告)日：2007-04-18
申请号：EP05772267.0
申请日：2005-07-18
发明人： BATES, Mark, C.
IPC分类号： A61M31/00
CPC分类号： A61B17/3478 , A61B2017/00247 , A61B2017/00398 , A61B2017/00871 , A61B2017/3411 , A61B2017/3484 , A61B2018/00392 , A61M5/3287
摘要： Apparatus (30) are provided for treating damaged tissue using apparatus that atraumatically delivers a bioactive agent within the tissue, wherein the apparatus provides a column of stem cells maybe advanced simultaneously with a needle during needle insertion, and then held stationary or injected at low pressure while retracting the needle. Alternatively, the needle may employ electromotive forces, or to change a dimension of the needle, to expel the bioactive agent into the needle track.
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8.发明公开INTERVENTIONAL CATHETER FOR RETROGRADE USE HAVING EMBOLIC PROTECTION CAPABILITY AND METHODS OF USE 审中-公开复古GRADES介入导管，栓塞保护和使用方法使用
公开(公告)号：EP1968687A2
公开(公告)日：2008-09-17
申请号：EP06847981.5
申请日：2006-12-20
发明人： BATES, Mark, C.
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2/90 , A61F2/958 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/008 , A61F2230/0097 , A61F2250/0039
摘要： Interventional catheters are disclosed for use in performing diagnostic and therapeutic procedures in vessels that are accessed retrograde to blood flow. The catheters include an elongated shaft slidably disposed within a sheath, a distal region having an end effector and a filter disposed proximal to the end effector to capture emboli liberated during the diagnostic or therapeutic procedure. The filter includes a plurality of struts that cooperate with an exterior surface of the catheter to define a reservoir to retain captured emboli, the reservoir configured so that advancement of the sheath contracts the filter without squeezing or dislodging captured emboli beyond a distal end of the filter.
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9.发明公开DEVICE COMPRISING BIODEGRADABLE BISTABLE OR MULTISTABLE CELLS AND METHODS OF USE 审中-公开可生物降解的双稳态或多设备多稳定的细胞及其使用方法
公开(公告)号：EP1962721A2
公开(公告)日：2008-09-03
申请号：EP06848074.8
申请日：2006-12-21
IPC分类号： A61F2/06
CPC分类号： A61B17/11 , A61F2/0009 , A61F2/064 , A61F2/91 , A61F2/915 , A61F2002/30062 , A61F2002/828 , A61F2002/91541 , A61F2002/91558 , A61F2002/91575 , A61F2210/0004 , A61F2230/0013 , B23K2203/42 , B23K2203/50 , B33Y80/00
摘要： Expandable biodegradable devices formed of bistable and multistable unit cells for use in devices, such as stents and graft systems, are provided, in which the device has two or more stable configurations, including a contracted configuration and an expanded configuration, the contracted stable configuration having a smaller diameter than the expanded configuration.
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10.发明公开IMPLANTABLE DEVICE FOR TREATING DISEASE STATES AND METHODS OF USING SAME 审中-公开可植入装置的疾病状态的治疗和使用它们的方法
公开(公告)号：EP1761204A2
公开(公告)日：2007-03-14
申请号：EP05757409.7
申请日：2005-06-07
发明人： BATES, Mark, C.
IPC分类号： A61F2/02
CPC分类号： A61M31/002 , A61B17/12109 , A61B17/12172 , A61B17/12177 , A61B17/12181 , A61B17/1219 , A61B2017/00889 , A61F2/022 , A61F2/86 , A61L29/16 , A61L31/16 , A61L2300/252 , A61L2300/258 , A61L2300/406 , A61L2300/416 , A61L2300/42 , A61L2300/43 , A61L2300/45 , A61L2300/64 , A61M25/04
摘要： Methods and apparatus are provided for delivering drugs, gene vectors, naturally-occurring or synthetic hormones or proteins or other bioactive agents within a patient's vasculature. In a preferred embodiment, the apparatus comprises a material that elutes or secretes a bioactive agent and is held in place within the patient's vessel by an anchor. The material may comprise a biocompatible, and optionally, absorbable matrix, or a culture medium that sustains and nourishes stem cells, spleen cells or pancreatic islets or other beneficial cells. The anchor and material are sized and/or collapsible from a delivery configuration, in which the anchor and material may be delivered into the patient's vasculature within a delivery sheath, to a deployed configuration, wherein the anchor engages an interior wall of the patient's vessel. The apparatus of the invention may be temporarily or permanently implanted, and may in addition self reconfigure after a predetermined period of residency.
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