公开(公告)号：EP1546107B1

公开(公告)日：2010-03-31

申请号：EP03795019.3

申请日：2003-09-12

申请人： GLAXO GROUP LIMITED ,  Beswick, Paul ,  Modi, Sandeep ,  Pegg, Neil ,  Skidmore, John ,  Swarbrick, Martin

发明人： BESWICK, Paul ,  MODI, Sandeep ,  PEGG, Neil ,  SKIDMORE, John ,  SWARBRICK, Martin

IPC分类号： C07D213/64 ,  A61K31/4418 ,  A61P29/00 ,  C07D213/74 ,  C07D401/12 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12 ,  C07D409/12

CPC分类号： C07D213/74 ,  C07D213/64 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D405/12

摘要： Compounds of formula (I) or pharmaceutically acceptable salts thereof are potent and selective inhibitors of COX-2 and are of use in the treatment of the pain, fever and inflammation of a variety of conditions and diseases.

公开(公告)号：EP1546107A1

公开(公告)日：2005-06-29

申请号：EP03795019.3

申请日：2003-09-12

申请人： GLAXO GROUP LIMITED ,  Beswick, Paul ,  Modi, Sandeep ,  Pegg, Neil ,  Skidmore, John ,  Swarbrick, Martin

发明人： BESWICK, Paul ,  MODI, Sandeep ,  PEGG, Neil ,  SKIDMORE, John ,  SWARBRICK, Martin

IPC分类号： C07D213/64 ,  A61K31/4418 ,  A61P29/00 ,  C07D213/74 ,  C07D401/12 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12 ,  C07D409/12

CPC分类号： C07D213/74 ,  C07D213/64 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D405/12

摘要： Compounds of formula (I) or pharmaceutically acceptable salts thereof are potent and selective inhibitors of COX-2 and are of use in the treatment of the pain, fever and inflammation of a variety of conditions and diseases.