公开(公告)号：EP1676107A4

公开(公告)日：2008-03-26

申请号：EP04794678

申请日：2004-10-12

Applicant: STHENO CORP

Inventor： GIBBS PHILLIP R

IPC: G01J4/00 ,  G01N21/19 ,  G01N21/21 ,  G02B20060101

CPC classification number: G01N21/21 ,  G01N21/19

Abstract: A differential method has been developed which determines displacement from a defined point of optical transmission (e.g., ±45° from null, or null 90° and parallel 0°) and utilizes the coupled nature of the two signals for common mode noise rejection and signal enhancement. A beam of light (104) is modulated (130), applied to the chiral mixture (140), and then split into a first beam (146) and a related orthogonal beam (148) by a polarizer or prism (142). The first beam (146) and orthogonal beam (148) are converted into electrical signals (150) (152) before a differential comparison (170) of the signals is performed to detect a desired chiral species within the chiral mixture.