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公开(公告)号：EP1594454B1
公开(公告)日：2016-07-27
申请号：EP04710305.6
申请日：2004-02-12
CPC分类号： A61K8/046 , A61K8/35 , A61K8/37 , A61K8/8158 , A61Q17/04
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公开(公告)号：EP1917072A2
公开(公告)日：2008-05-07
申请号：EP06755917.9
申请日：2006-05-26
发明人： ABRAM, Alby , BUCHTA, Richard , HOULDEN, Robert, James , YE, Rose
IPC分类号： A61P17/06 , A61K9/12 , A61K31/203 , A61K9/107 , A61K31/202 , A61P17/00
CPC分类号： A61K9/122 , A61K9/0014 , A61K9/107 , A61K31/202 , A61K31/203 , A61K47/22 , A61K2300/00
摘要： A pharmaceutical aerosol foam composition, comprising an effective amount of a pharmaceutically active ingredient, wherein said pharmaceutically active ingredient is a vitamin or analogue thereof; an occlusive agent; an aqueous solvent; an organic co-solvent; wherein the pharmaceutically active ingredient is insoluble in both water and the occlusive agent; and the occlusive agent being present in an amount sufficient to form an occlusive layer on the skin, in use. The pharmaceutically active ingredient can be selected from vitamin D3 and vitamin A and/or their analogues such as calcipotriene, tretinoin, acitretin, etc. In a second embodiment, an oil-in-water emulsion having a vitamin; an occlusive agent; an aqueous solvent; and an organic co-solvent, wherein the occlusive agent is present in an amount sufficient to foam an occlusive layer on the skin. The composition can be used to treat dermatological disorders such as psoriasis.
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公开(公告)号：EP1695708B1
公开(公告)日：2018-02-28
申请号：EP06012033.4
申请日：1999-04-20
IPC分类号： A61K31/505 , A61K31/506 , A61P17/14 , A61K47/12 , A61K8/49 , A61K9/00 , A61Q7/00 , A61K47/10
CPC分类号： A61K47/12 , A61K8/4953 , A61K9/0014 , A61K31/506 , A61K47/10 , A61Q7/00 , Y10S514/88 , Y10S514/94 , Y10S514/946 , Y10S514/947
摘要： A pharmaceutical composition for topical administration, including, as the pharmaceutically active component, at least 5% by weight, based on the total weight of the composition of a piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; an acid in an amount to completely solubilise the piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; a solvent composition including at least two of water, a lower alcohol and a co-solvent selected from one or more of the group consisting of aromatic and polyhydric alcohols; wherein when the co-solvent includes propylene glycol, it is present in an amount of less than approximately 10% by weight.
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公开(公告)号：EP2741733A1
公开(公告)日：2014-06-18
申请号：EP12822519.0
申请日：2012-08-10
CPC分类号： A61Q19/00 , A61K8/046 , A61K8/34 , A61K8/342 , A61K8/676 , A61K8/86 , A61K2800/522 , A61Q19/08
摘要： The present invention relates to topical aerosol compositions comprising L-ascorbic acid. The compositions comprise (a) L-ascorbic acid, or a pharmaceutically acceptable salt or ester thereof, (b) water, (c) lower alcohol and (d) an aerosol propellant. In particular embodiments of the invention, the formulations are actuated as an aerosol spray or aerosol foam. The formulations are suitable for minimizing aging of the skin.
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公开(公告)号：EP1592420B1
公开(公告)日：2014-01-01
申请号：EP04704507.5
申请日：2004-01-23
CPC分类号： A61K8/046 , A61K8/38 , A61K8/671 , A61K9/12 , A61K9/122 , A61K31/4025 , A61K45/06 , A61Q19/00 , A61K2300/00
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公开(公告)号：EP2408299B1
公开(公告)日：2013-10-23
申请号：EP10754148.4
申请日：2010-03-19
发明人： LENN, Jon , HUNT, Barry , HSIA, Edward , HOFLAND, Hans
CPC分类号： A61K31/22 , A61K9/0014 , A61K9/12 , A61K9/7015 , A61K31/517 , A61K2300/00
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公开(公告)号：EP2408299A1
公开(公告)日：2012-01-25
申请号：EP10754148.4
申请日：2010-03-19
发明人： LENN, Jon , HUNT, Barry , HSIA, Edward , HOFLAND, Hans
CPC分类号： A61K31/22 , A61K9/0014 , A61K9/12 , A61K9/7015 , A61K31/517 , A61K2300/00
摘要： The present invention relates to a method of treating a fungal condition caused by
T. rubrum , by administering a composition comprising a fatty acid monoester of glycerol. According to an embodiment, the fatty acid monoester of glycerol is 1-monocaprin. According to another embodiment, the fungal condition is onychomycosis摘要翻译： 本发明涉及通过施用包含甘油的脂肪酸单酯的组合物治疗由红色毛癣菌引起的真菌病症的方法。 根据一个实施方案，甘油的脂肪酸单酯是1-癸酸甘油酯。 根据另一个实施方案，真菌病症是甲癣
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公开(公告)号：EP2046121A2
公开(公告)日：2009-04-15
申请号：EP07810355.3
申请日：2007-07-12
CPC分类号： A61K9/122 , A61K9/0014 , A61K9/12 , A61K9/124 , A61K31/437 , A61K31/4745 , A61K47/12 , A61K47/14 , A61K47/18
摘要： The present invention provides a foamable composition comprising water and an organic solvent, wherein the organic solvent comprises a fatty acid. The composition may further comprise a pharmaceutically active agent. The composition of the invention is also useful for the treatment of a dermatological disorder in a mammal by the topical administration of the composition.
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9.发明授权
公开(公告)号：EP1796636B2
公开(公告)日：2016-12-14
申请号：EP05775966.4
申请日：2005-08-31
发明人： LARM, Maria, Graziella , HARDING, Ronald , VIJAYAKUMAR, Prema , ABRAM, Albert, Zorko , JOHNSTON, Michael , SUN, Phoebe
CPC分类号： A61K31/56 , A61K8/062 , A61K8/068 , A61K9/0014 , A61K9/107 , A61K9/1075 , A61K9/12 , A61K31/59 , A61Q19/00
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公开(公告)号：EP1594454B8
公开(公告)日：2016-10-12
申请号：EP04710305.6
申请日：2004-02-12
CPC分类号： A61K8/046 , A61K8/35 , A61K8/37 , A61K8/8158 , A61Q17/04
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