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公开(公告)号:EP1695708B1
公开(公告)日:2018-02-28
申请号:EP06012033.4
申请日:1999-04-20
IPC分类号: A61K31/505 , A61K31/506 , A61P17/14 , A61K47/12 , A61K8/49 , A61K9/00 , A61Q7/00 , A61K47/10
CPC分类号: A61K47/12 , A61K8/4953 , A61K9/0014 , A61K31/506 , A61K47/10 , A61Q7/00 , Y10S514/88 , Y10S514/94 , Y10S514/946 , Y10S514/947
摘要: A pharmaceutical composition for topical administration, including, as the pharmaceutically active component, at least 5% by weight, based on the total weight of the composition of a piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; an acid in an amount to completely solubilise the piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; a solvent composition including at least two of water, a lower alcohol and a co-solvent selected from one or more of the group consisting of aromatic and polyhydric alcohols; wherein when the co-solvent includes propylene glycol, it is present in an amount of less than approximately 10% by weight.
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公开(公告)号:EP1695708A3
公开(公告)日:2012-07-18
申请号:EP06012033.4
申请日:1999-04-20
IPC分类号: A61K31/505 , A61K31/506 , A61P17/14 , A61K47/12 , A61K8/49 , A61K9/00 , A61Q7/00 , A61K47/10
CPC分类号: A61K47/12 , A61K8/4953 , A61K9/0014 , A61K31/506 , A61K47/10 , A61Q7/00 , Y10S514/88 , Y10S514/94 , Y10S514/946 , Y10S514/947
摘要: A pharmaceutical composition for topical administration, including, as the pharmaceutically active component, at least 5% by weight, based on the total weight of the composition of a piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; an acid in an amount to completely solubilise the piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; a solvent composition including at least two of water, a lower alcohol and a co-solvent selected from one or more of the group consisting of aromatic and polyhydric alcohols; wherein when the co-solvent includes propylene glycol, it is present in an amount of less than approximately 10% by weight.
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