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公开(公告)号：EP1439843A2
公开(公告)日：2004-07-28
申请号：EP02776131.1
申请日：2002-10-04
发明人： HLAVKA, Joseph , ABLIN, Richard, J.
IPC分类号： A61K31/65
CPC分类号： A61K31/65 , C07C237/26 , C07C2603/46
摘要： A treatment for inhibiting microbial or tumor growth is disclosed, which comprises adding to a subject in need of treatment an effective amount of one or more tetracycline derivatives.
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公开(公告)号：EP1894569A3
公开(公告)日：2008-05-07
申请号：EP07117753.9
申请日：2002-10-04
发明人： Hlavka, Joseph , Ablin, Richard J.
CPC分类号： A61K31/65 , C07C237/26 , C07C2603/46
摘要： The invention is directed to the use of the compounds 9-amino- and 9-nitro-6-deoxy-5-hydroxytetracycline and of salts of these compounds for the treatment of cancer, especially of prostate cancer, breast cancer, melanoma or myeloma.
摘要翻译： 本发明涉及化合物9-氨基 - 和9-硝基-6-脱氧-5-羟基四环素以及这些化合物的盐用于治疗癌症，特别是前列腺癌，乳腺癌，黑素瘤或骨髓瘤的用途。
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3.发明公开
公开(公告)号：EP1894569A2
公开(公告)日：2008-03-05
申请号：EP07117753.9
申请日：2002-10-04
发明人： Hlavka, Joseph , Ablin, Richard J.
CPC分类号： A61K31/65 , C07C237/26 , C07C2603/46
摘要： The invention is directed to the use of the compounds 9-amino- and 9-nitro-6-deoxy-5-hydroxytetracycline and of salts of these compounds for the treatment of cancer, especially of prostate cancer, breast cancer, melanoma or myeloma.
摘要翻译： 本发明涉及化合物9-氨基 - 和9-硝基-6-脱氧-5-羟基四环素和这些化合物的盐用于治疗癌症，特别是前列腺癌，乳腺癌，黑素瘤或骨髓瘤的用途。
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4.发明公开TETRACYCLINE DERIVATIVES AND METHODS OF USE THEREOF 审中-公开TETRACYCLIN-DERIVATE UND ANWENDUNGSVERFAHREN
公开(公告)号：EP1439843A4
公开(公告)日：2007-01-03
申请号：EP02776131
申请日：2002-10-04
发明人： HLAVKA JOSEPH , ABLIN RICHARD J
IPC分类号： A61K31/65 , A61K31/655 , A61P31/04 , A61P35/00 , C07C235/84 , C07C237/26
CPC分类号： A61K31/65 , C07C237/26 , C07C2603/46
摘要： A treatment for inhibiting microbial or tumor growth is disclosed, which comprises adding to a subject in need of treatment an effective amount of one or more tetracycline derivatives.
摘要翻译： 公开了抑制微生物或肿瘤生长的治疗方法，其包括将需要治疗的受试者加入有效量的一种或多种四环素衍生物。
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