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公开(公告)号：EP0548123A1
公开(公告)日：1993-06-30
申请号：EP91915601.0
申请日：1991-06-12
发明人： BECK, Lee, R.
CPC分类号： A23C9/20 , A24B15/30 , A61K9/1647 , A61K35/20 , A61K35/74 , A61K39/39508 , C07K2317/11
摘要： The invention relates to a substantially pure anti-inflammatory factor isolated from milk collected from a milk producing animal, to the purification, identification, and characterization of said factor, and to a method for treating inflammation in an animal which comprises administering to the animal an anti-inflammatorally effective amount of the anti-inflammatory factor. In a preferred embodiment, the factor is isolated from milk is produced by a milk producing animal maintained in a hyperimmunized state.
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2.发明授权Use of hyperimmune milk for the manufacture of a medicament for the treatment of cardio-vascular diseases or for lowering lipid bloodstream levels 失效用于制造用于治疗心血管疾病或降低脂质血红蛋白水平的药物的高胰岛素的使用
公开(公告)号：EP0143345B1
公开(公告)日：1991-06-19
申请号：EP84112946.3
申请日：1984-10-26
发明人： Stolle, Ralph J. , Beck, Lee R Dr.
IPC分类号： A61K35/20 , A61K39/395 , A23C9/20 , A23C9/123 , A24B15/30
CPC分类号： A61K39/39508 , A23C9/20 , A23L33/10 , A23V2002/00 , A24B15/30 , A61K35/20 , C07K2317/11 , A23V2200/324 , A23V2250/5424
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公开(公告)号：EP0135951B1
公开(公告)日：1991-06-19
申请号：EP84201097.7
申请日：1984-07-26
发明人： Stolle, Ralph J. , Beck, Lee R.
IPC分类号： A61K39/00
CPC分类号： A61K39/092 , A61K39/085 , A61K2039/552 , Y10S424/823
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4.发明公开Improved method of obtaining immune regulatory factors by mammal immunization 失效Verfahren zum Erhalten von immunregulierenden Faktoren mittelsSäugetierimmunisierung。
公开(公告)号：EP0300102A1
公开(公告)日：1989-01-25
申请号：EP87306455.4
申请日：1987-07-21
发明人： Beck, Lee R.
IPC分类号： A61K39/00
CPC分类号： A61K9/1647 , A61K38/00 , C07K14/52 , C07K16/04
摘要： Immune regulatory factors, eg. antibodic and lymphokinens, are obtained by collecting or extracting immune regulatory factors containing substances, eg. milk, from mammals, especially bovids, immunized by administering an antigenic substance incorporated within a shaped structure of a biocompatible matrix material. The matrix material causes controlled release of the antigenic substance thereby prolonging antigenic activity within the treated animal.
摘要翻译： 免疫调节因子，例如 抗生素和淋巴母细胞通过收集或提取含有物质的免疫调节因子获得，例如。 通过施用结合在生物相容性基质材料的成形结构内的抗原物质免疫的来自哺乳动物，尤其是牛奶的牛奶。 基质材料导致抗原物质的受控释放，从而延长了治疗动物内的抗原活性。
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5.发明公开Method of passive immunization of mammals using avian and/or bovid antibody and compositions for same 失效使用AVIAN和/或BOVID抗体及其组合物对哺乳动物进行被动免疫的方法
公开(公告)号：EP0152270A3
公开(公告)日：1988-01-27
申请号：EP85300786
申请日：1985-02-06
发明人： Stolle, Ralph J. , Beck, Lee R.
IPC分类号： C07K15/00 , A61K39/395
CPC分类号： C07K16/04 , A61K2039/505 , A61K2039/507 , A61K2039/542 , C07K16/02 , C07K16/1275 , C07K2317/23
摘要： A method of passively immunizing a mammal against a condition caused by an antigen comprising: administering to the mammal immunizing amounts of an antibody obtained from a domesticated fowl or bovid which has been immunized against the antigen: the mammal being tolerant to the antibody by virtue of having a history of consumption of antibody containing material derived from the egg of a fowl or milk of a bovid.
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公开(公告)号：EP0123326A2
公开(公告)日：1984-10-31
申请号：EP84200259.4
申请日：1984-02-24
发明人： Meyers, William E. , Beck, Lee R.
摘要： @ A cell culture device is disclosed for the cultivation of animal, plant, mocrobiological or artificial cells. The device involves a three-dimensional arrangement of fibers within a housing arranged to provide maximum exposed fiber surface flow channel diameter while also reducing the tortuosity of the flow path. Cells are bound to the fibers to allow them to contact nutrient fluid solution and thereby to remove any substances originating in said cells, such as viruses and pharmaceuticals.
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7.发明公开Method of obtaining an anti-inflammatory bovine milk 失效Verfahren zur Herstellung einerentzündungshemmendenRindermilch。
公开(公告)号：EP0064103A1
公开(公告)日：1982-11-10
申请号：EP81301877.7
申请日：1981-04-28
发明人： Beck, Lee R.
IPC分类号： A61K39/40 , A61K39/395
摘要： An anti-inflammatory product is provided by or obtained from milk collected from a bovid maintained in a specific hyperimmune state by administering periodic booster doses of an antigen or mixture of antigens.
摘要翻译： 通过施用定期加强剂量的抗原或抗原混合物，从维持在特定超免疫状态的牛中收集的牛提供抗炎产物或从其获得。
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8.发明授权Use of milk for the manufacture of a hyperimmune milk composition for treating disorders of the pulmonary system in mammals 失效用于生产超免疫乳化合物用于在哺乳动物中的呼吸系统疾病的治疗使用的牛奶。
公开(公告)号：EP0380032B1
公开(公告)日：1994-01-19
申请号：EP90101230.2
申请日：1984-10-26
IPC分类号： A61K35/20 , A61K39/395 , A23C9/20 , A23C9/123 , A24B15/30
CPC分类号： A61K39/39508 , A23C9/20 , A23L33/10 , A23V2002/00 , A24B15/30 , A61K35/20 , C07K2317/11 , A23V2200/324 , A23V2250/5424
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公开(公告)号：EP0548123A4
公开(公告)日：1993-12-08
申请号：EP91915601
申请日：1991-06-12
发明人： BECK, LEE, R.
IPC分类号： A61K38/00 , A23C9/20 , A24B15/30 , A61K9/16 , A61K35/20 , A61K35/54 , A61K35/74 , A61K39/395 , A61P29/00 , C07K14/47
CPC分类号： A23C9/20 , A24B15/30 , A61K9/1647 , A61K35/20 , A61K35/74 , A61K39/39508 , C07K2317/11
摘要： The invention relates to a substantially pure anti-inflammatory factor isolated from milk collected from a milk producing animal, to the purification, identification, and characterization of said factor, and to a method for treating inflammation in an animal which comprises administering to the animal an anti-inflammatorally effective amount of the anti-inflammatory factor. In a preferred embodiment, the factor is isolated from milk is produced by a milk producing animal maintained in a hyperimmunized state.
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10.发明授权
公开(公告)号：EP0102265B1
公开(公告)日：1992-07-08
申请号：EP83401489.6
申请日：1983-07-20
CPC分类号： A61K9/1694 , A61K9/1647
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