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公开(公告)号:EP2751287A1
公开(公告)日:2014-07-09
申请号:EP12780105.8
申请日:2012-10-01
申请人: Université Montpellier 2, Sciences et Techniques , Institut Curie , INSERM (Institut National de la Santé et de la Recherche Scientifique) , Centre Hospitalier Universitaire de Montpellier , Centre National de la Recherche Scientifique , Université Montpellier I
发明人: JOUBERT, Dominique , BAUCHET, Luc , HUGNOT, Jean-Philippe , BIECHE, Ivan , LIDEREAU, Rosette , REME, Thierry , DUFFAU, Hugues , RIGAU, Valérie
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G06F19/20 , G16H50/30
摘要: Disclosed is a method of determining the survival prognosis of a patient afflicted by a glioma. The method includes assessing the level of expression of one or more specific gene in cells of the glioma.
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公开(公告)号:EP2596013A1
公开(公告)日:2013-05-29
申请号:EP11736085.9
申请日:2011-07-21
申请人: Université Montpellier 2 Sciences et Techniques , Institut Curie , INSERM - Institut National de la Santé et de la Recherche Médicale , Centre Hospitalier Universitaire de Montpellier , Centre National de la Recherche Scientifique
发明人: HUGNOT, Jean-Philippe , GUICHET, Pierre-Olivier , TEIGELL, Marisa , BIECHE, Yvan , LIDEREAU, Rosette , JOUBERT, Dominique , BAUCHET, Luc , RIGAU, Valérie
IPC分类号: C07K14/47 , C07K16/18 , C12N15/113 , C12N15/115 , A61K31/713
CPC分类号: C12N15/113 , A61K31/713 , A61K45/06 , C12N15/115 , C12N2310/11 , C12N2310/14 , C12N2310/16 , C12N2310/531
摘要: The present invention relates to NKX2.2 inhibitors such as shRNAs for treating pathologies.
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公开(公告)号:EP2542584A2
公开(公告)日:2013-01-09
申请号:EP11700115.6
申请日:2011-01-07
申请人: Bioréalités , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , Centre National de la Recherche Scientifique (CNRS)
IPC分类号: C07K16/26 , A61K39/395 , A61P35/00
CPC分类号: C07K16/26 , A61K39/39558 , C07K16/303 , C07K2317/34 , C07K2317/73 , G01N33/57438 , G01N2333/595 , G01N2800/52
摘要: The present disclosure is directed to methods of treating pancreatic cancer in subject using cancer with antibodies that specifically bind to progastrin.
摘要翻译: 本公开涉及用特异性结合前胃泌素的抗体使用癌症治疗受试者胰腺癌的方法。
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公开(公告)号:EP3296319A1
公开(公告)日:2018-03-21
申请号:EP17197865.3
申请日:2011-01-07
申请人: Centre National de la Recherche Scientifique (CNRS) , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , Progastrine et Cancers S.à r.l.
发明人: PANNEQUIN, Julie , HOUHOU, Leila , FRAMERY, Berenice , ERKILIC, Nejla , JOUBERT, Dominique , HOLLANDE, Frederic
IPC分类号: C07K16/26 , A61K39/395 , A61P35/00
CPC分类号: C07K16/26 , A61K39/39558 , A61K2039/505 , C07K5/1016 , C07K16/3046 , C07K2317/24 , C07K2317/73 , C07K2317/76 , G01N33/57419 , G01N2333/595 , G01N2800/52
摘要: The present disclosure is directed to methods of treating and preventing colorectal cancer metastasis or recurrence of colorectal cancer with compositions comprising anti-progastrin antibodies.
摘要翻译: 本公开涉及用包含抗前胃泌素抗体的组合物治疗和预防结肠直肠癌转移或结直肠癌复发的方法。
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公开(公告)号:EP2542584B8
公开(公告)日:2017-12-13
申请号:EP11700115.6
申请日:2011-01-07
申请人: Progastrine et Cancers S.à r.l. , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , Centre National de la Recherche Scientifique (C.N.R.S.)
IPC分类号: C07K16/26 , A61K39/395 , A61P35/00
CPC分类号: C07K16/26 , A61K39/39558 , C07K16/303 , C07K2317/34 , C07K2317/73 , G01N33/57438 , G01N2333/595 , G01N2800/52
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公开(公告)号:EP2550294B1
公开(公告)日:2019-08-21
申请号:EP11710711.0
申请日:2011-03-23
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公开(公告)号:EP2550294A2
公开(公告)日:2013-01-30
申请号:EP11710711.0
申请日:2011-03-23
申请人: Bioréalités , Institut National de la Santé et de la Recherche Médicale - Inserm , Centre National de la Recherche Scientifique CNRS
CPC分类号: C07K16/26 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/57419 , G01N33/57488 , G01N33/74 , G01N2333/5758 , G01N2333/595 , G01N2800/52
摘要: The present disclosure provides methods and compositions useful for preventing gastrointestinal and/or colorectal cancer in animals, including humans, having pre-cancerous adenomatous polyps. The present disclosure provides compositions comprising anti-PG antibodies suitable for use in the methods of the disclosure. The present disclosure also provides methods and compositions useful for monitoring the efficacy of anti-PG treatment in subjects with pre-cancerous polyps.
摘要翻译: 本公开提供了用于预防具有癌前腺瘤性息肉的动物(包括人)中的胃肠和/或结肠直肠癌的方法和组合物。 本公开提供了包含适合用于本公开的方法的抗PG抗体的组合物。 本公开还提供了可用于监测具有癌前息肉的受试者中抗PG治疗的功效的方法和组合物。
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公开(公告)号:EP2542585A2
公开(公告)日:2013-01-09
申请号:EP11704178.0
申请日:2011-01-07
申请人: Bioréalités , INSERM - Institut National de la Santé et de la Recherche Médicale , Centre National de la Recherche Scientifique CNRS
发明人: PANNEQUIN, Julie , HOUHOU, Leïla , FRAMERY, Bérénice , ERKILIC, Nejla , JOUBERT, Dominique , HOLLANDE, Frédéric
IPC分类号: C07K16/26
CPC分类号: C07K16/26 , A61K39/39558 , A61K2039/505 , C07K5/1016 , C07K16/3046 , C07K2317/24 , C07K2317/73 , C07K2317/76 , G01N33/57419 , G01N2333/595 , G01N2800/52
摘要: The present disclosure is directed to methods of treating and preventing colorectal cancer metastasis or recurrence of colorectal cancer with compositions comprising anti-progastrin antibodies.
摘要翻译: 本公开涉及用包含抗前泌肽抗体的组合物治疗和预防结肠直肠癌转移或结肠直肠癌复发的方法。
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公开(公告)号:EP2040753B8
公开(公告)日:2019-04-10
申请号:EP07734620.3
申请日:2007-05-21
申请人: INSERM (Institut National de la Santé et de la Recherche Médicale) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- , Université de Montpellier
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公开(公告)号:EP2040753B1
公开(公告)日:2019-02-27
申请号:EP07734620.3
申请日:2007-05-21
申请人: INSERM (Institut National de la Santé et de la Recherche Médicale) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- , Université de Montpellier
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